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Study demonstrates rarity of familial hypercholesterolemia mutations in individuals with high cholesterol

Only a small fraction of people with very high cholesterol can attribute their condition to a genetic mutation related to familial hypercholesterolemia, but individuals with these mutations face a high risk of developing early-onset coronary artery disease, according to research presented at the American College of Cardiology's 65th Annual Scientific Session.

4 Apr 2016

Liu Laboratory at Augusta University studies exosomes using Particle Metrix’s ZetaView

Particle Metrix, developers of versatile particle characterization solutions for the life sciences, report on the work in the Liu Laboratory at Augusta University which is studying exosomes where size and concentration are critical parameters.

4 Apr 2016

Heart disease patients who experience mental stress ischemia tend to have higher levels of troponin

Some people with heart disease experience a restriction of blood flow to the heart in response to psychological stress. Usually silent (not painful), the temporary restriction in blood flow, called ischemia, is an indicator of greater mortality risk.

4 Apr 2016

Leading entrepreneurs, innovators to take part in Royal Society of Medicine's 12th Medical Innovations Summit

A group of leading entrepreneurs and innovators will be gathering at the Royal Society of Medicine on Saturday 16 April to take part in the Society’s 12th Medical Innovations Summit. Providing a twice-yearly platform for the presentation and discussion of inspirational ideas and developments in the field of medicine and healthcare, the Summits encourage innovators at the very beginning of their careers, as well as established clinicians and academics.

4 Apr 2016

Andor’s sCMOS camera leads to new microscopy method

An innovative microfabrication technique used to produce a mirror array that both directs the excitation beam and holds the sample may revolutionise the field of 3D super-resolution microscopy, according to an international group of scientists.

From Andor Technology Ltd. 4 Apr 2016

Study findings strongly point to independent control of sensory neurons during motor learning

Sensory neurons in human muscles provide important information used for the perception and control of movement. Learning to move in a novel context also relies on the brain's independent control of these sensors, not just of muscles, according to a new study published in the journal Current Biology.

2 Apr 2016

Joslin scientists identify new mechanism in development of obesity-induced insulin resistance

In obesity, the body's immune system can treat tissues as if they are suffering from a low-grade chronic infection. This obesity-induced inflammation is an important contributor to insulin resistance, a condition that can progress into type 2 diabetes.

2 Apr 2016

U of S-led researchers develop novel class of compounds for effective cancer treatment

A novel class of compounds developed by a University of Saskatchewan-led research team could yield more effective and less toxic chemotherapy drugs to treat cancer.

2 Apr 2016

NTU researchers make breakthrough to tackle growing concern of antibiotic resistance

Scientists at Nanyang Technological University, Singapore have discovered that antibiotics can continue to be effective if bacteria's cell-to-cell communication and ability to latch on to each other are disrupted.

2 Apr 2016

Better understanding of cell death mechanism could lead to more efficient cancer immunotherapy

Researchers in the group of Prof. Dr. Peter Vandenabeele show that killed tumour cells can serve as a potent vaccine that stimulates the immune system to prevent the outgrowth of cancer cells.

2 Apr 2016

Lund researchers discover new biomarker that can predict type 2 diabetes risk

Researchers at Lund University in Sweden have found a new type of biomarker that can predict the risk of type 2 diabetes, by detecting epigenetic changes in specific genes through a simple blood test. The results are published today in Nature Communications.

2 Apr 2016

MicroRNA controls tumor cell proliferation in most aggressive large B-cell lymphoma

A recent study by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine showed that a microRNA called miR-181a dampens signals from the cancer-driving NFκB protein pathway in the most aggressive large B-cell lymphomas (DLBCL). By reducing NFκB signaling, miR-181a controls tumor cell proliferation and survival and could be the target of novel therapies. The study was published in the journal Blood.

2 Apr 2016

Common viruses could produce mild to lethal cardiac injury

A review article has been published in the journal Current Pharmaceutical Design which provides an overview of therecent literature discussing the different clinical forms of heart disease resulting from virus infections including the prognosis, and current therapies.

2 Apr 2016

HDAC inhibitors could improve activity of immunotherapeutic antibodies in lung cancer patients

Several new immunotherapeutic antibodies that inhibit checkpoint receptors on T cells to restimulate the immune system to target tumors have been approved to treat advanced stage lung cancer and melanoma; however, only 20 percent of lung cancer patients show a response to these agents.

2 Apr 2016

Researchers uncover vital clues of how the brain erases long term memories

Vital clues about how the brain erases long term memories have been uncovered by researchers. The study in rats reveals how forgetting can be the result of an active deletion process rather than a failure to remember.

2 Apr 2016

Altered metabolism of two essential amino acids helps drive development of glioblastoma

The altered metabolism of two essential amino acids helps drive the development of the most common and lethal form of brain cancer, according to a new study led by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.

2 Apr 2016

Excess activation of LOX may play causative role in progression of cardiac failure

Heart failure is a progressive condition, where structural and functional alterations of the ventricle limit the ability of the heart to either fill or eject blood. There are approximately 550,000 new cases of heart failure each year with a prevalence of nearly 5 million; most patients die within five years of diagnosis.

2 Apr 2016

New study raises possibility of therapeutic intervention for brain blood vessel disease

Cerebral cavernous malformations (CCM) are the most common cause of stroke in young people. These malformations also known as Cavernomas are present in 0.1-0.5% of the population, with about 60% causing symptoms. Currently there is no drug treatment available for CCM.

1 Apr 2016

German scientists use DNA molecules to make nanoscale component

In order for a machine to perform work, it needs parts that move relative to each other. This also holds true for nanoscale machines. German scientists have now used DNA molecules to make a nanoscale component that makes it possible for two individual parts to move relative to each other. As reported in the journal Angewandte Chemie, this component could be used as a molecular guide bearing and may form the basis for more complex systems.

1 Apr 2016

Study may help identify unborn children at higher risk for birth defects

Researchers at the University of Toronto have discovered a novel function performed by the breast cancer 1 protein (BRCA1), which regulates DNA repair. Well known for the role it plays in breast and ovarian cancer, this study revealed that the BRCA1 protein actually plays a much broader biological role, particularly in protecting the developing embryo from the damaging effects of reactive oxygen species (ROS).

1 Apr 2016

Medical Science News

Study demonstrates rarity of familial hypercholesterolemia mutations in individuals with high cholesterol

Liu Laboratory at Augusta University studies exosomes using Particle Metrix’s ZetaView

Heart disease patients who experience mental stress ischemia tend to have higher levels of troponin

Leading entrepreneurs, innovators to take part in Royal Society of Medicine's 12th Medical Innovations Summit

Andor’s sCMOS camera leads to new microscopy method

Study findings strongly point to independent control of sensory neurons during motor learning

Joslin scientists identify new mechanism in development of obesity-induced insulin resistance

U of S-led researchers develop novel class of compounds for effective cancer treatment

NTU researchers make breakthrough to tackle growing concern of antibiotic resistance

Better understanding of cell death mechanism could lead to more efficient cancer immunotherapy

Lund researchers discover new biomarker that can predict type 2 diabetes risk

MicroRNA controls tumor cell proliferation in most aggressive large B-cell lymphoma

Common viruses could produce mild to lethal cardiac injury

HDAC inhibitors could improve activity of immunotherapeutic antibodies in lung cancer patients

Researchers uncover vital clues of how the brain erases long term memories

Altered metabolism of two essential amino acids helps drive development of glioblastoma

Excess activation of LOX may play causative role in progression of cardiac failure

New study raises possibility of therapeutic intervention for brain blood vessel disease

German scientists use DNA molecules to make nanoscale component

Study may help identify unborn children at higher risk for birth defects

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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