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Research points to new direction for potential therapies to treat mucoepidermoid carcinoma

Research conducted at the Florida campus of The Scripps Research Institute has discovered links between a set of genes known to promote tumor growth and mucoepidermoid carcinoma, an oral cancer that affects the salivary glands. The discovery could help physicians develop new treatments that target the cancer's underlying genetic causes.

29 Jul 2014

PLXNA4 gene may increase risk of developing Alzheimer's disease

Researchers from Boston University School of Medicine report variants in a new gene, PLXNA4, which may increase the risk of developing Alzheimer's disease (AD). The discovery of this novel genetic association may lead to new drug treatment options that target PLXNA4 specifically.

28 Jul 2014

Nicotine, cotinine can potentially inhibit DNA damage caused by NNK in tobacco smoke

A new in vitro study has revealed that nicotine and cotinine, a metabolite of nicotine, can potentially inhibit DNA damage caused by a certain carcinogen in smoke.

28 Jul 2014

Antifungal drug resistance evoked through RNAi-dependent epimutations

Microorganisms like bacteria and fungi can evade treatment by acquiring mutations in the genes targeted by antibiotics or antifungal drugs.

27 Jul 2014

Parallel brain circuits associated with opposing emotional reactions

People choosing between two or more equally positive outcomes experience paradoxical feelings of pleasure and anxiety, feelings associated with activity in different regions of the brain, according to research led by Amitai Shenhav, an associate research scholar at the Princeton Neuroscience Institute at Princeton University.

27 Jul 2014

Melatonin has protective effects on traumatic brain injury-induced cerebral cortex

Traumatic brain injury can cause post-traumatic neurodegenerations with an increase in reactive oxygen species and reactive oxygen species-mediated lipid peroxidation. Melatonin, a non-enzymatic antioxidant and neuroprotective agent, has been shown to counteract oxidative stress-induced pathophysiologic conditions like cerebral ischemia/reperfusion injury, neuronal excitotoxicity and chronic inflammation.

26 Jul 2014

Study provides potential drug targets for transient cerebral ischemia-reperfusion injury

Mitochondria play an important role in neuronal apoptosis caused by cerebral ischemia. Researchers at the Affiliated Hospital of Qingdao University, China discovered transient ischemia led to cell apoptosis in the hippocampus and changes in memory and cognition of aged rats.

26 Jul 2014

Neuroscientists shed new light on how the brain works

Neuroscientists in Bonn and Heidelberg have succeeded in providing new insights into how the brain works. Researchers at the DZNE and the German Cancer Research Center analyzed tissue samples from mice to identify how two specific proteins, ‘CKAMP44’ and ‘TARP Gamma-8’, act upon the brain’s memory center.

26 Jul 2014

Xbp1s protein plays key role in brain regions to regulate metabolism

A protein that controls when genes are switched on or off plays a key role in specific areas of the brain to regulate metabolism, UT Southwestern Medical Center researchers have found.

26 Jul 2014

Trials show immunizations are effective in adults

As kids prepare to head back to school, required immunizations are typically on the to-do list, but getting potentially lifesaving vaccines should not end when adulthood begins, says one University of Alabama at Birmingham infectious diseases expert.

26 Jul 2014

Montefiore-Einstein investigators to present new findings from eight abstracts at IFHNOS 2014

Clinicians and researchers from Montefiore Medical Center and the Albert Einstein College of Medicine of Yeshiva University will present new findings from eight abstracts at the International Federation of Head and Neck Oncologic Societies World Congress being held July 26 - July 30 in New York.

26 Jul 2014

Researchers reveal that Schlemm's canal shares features of lymphatic vessels

Glaucoma is one of the leading causes of blindness worldwide. A major risk factor for glaucoma is elevated eye pressure due to poor drainage of aqueous humor, the fluid that provides nutrients to the eye.

26 Jul 2014

Neuregulin 1 effective in promoting peripheral nerve regrowth

Neuregulin 1 (NRG1) is a pleiotropic factor characterized by the existence of numerous isoforms arising from alternative splicing of exons that confer to the protein deeply different characteristics.

26 Jul 2014

Researchers exploring ways to stimulate patients' immune system to attack tumors

Researchers at Dartmouth-Hitchcock Norris Cotton Cancer Center are exploring ways to wake up the immune system so it recognizes and attacks invading cancer cells. Tumors protect themselves by tricking the immune system into accepting everything as normal, even while cancer cells are dividing and spreading.

26 Jul 2014

Scientists discover new pathway to manipulate, maintain human ESCs in a "na-ve"

For years, researchers and patients have hoped that embryonic stem cells (ESCs)-capable of forming nearly any cell type in the body-could provide insight into numerous diseases perhaps even be used to treat them. Yet progress has been hampered by the inability to transfer research and tools from mouse ESC studies to their human counterparts, in part because human ESCs are "primed" and slightly less plastic than the mouse cells.

26 Jul 2014

Medical Science News

Research points to new direction for potential therapies to treat mucoepidermoid carcinoma

PLXNA4 gene may increase risk of developing Alzheimer's disease

Nicotine, cotinine can potentially inhibit DNA damage caused by NNK in tobacco smoke

Antifungal drug resistance evoked through RNAi-dependent epimutations

Parallel brain circuits associated with opposing emotional reactions

Melatonin has protective effects on traumatic brain injury-induced cerebral cortex

Study provides potential drug targets for transient cerebral ischemia-reperfusion injury

Neuroscientists shed new light on how the brain works

Xbp1s protein plays key role in brain regions to regulate metabolism

Trials show immunizations are effective in adults

Montefiore-Einstein investigators to present new findings from eight abstracts at IFHNOS 2014

Researchers reveal that Schlemm's canal shares features of lymphatic vessels

Neuregulin 1 effective in promoting peripheral nerve regrowth

Researchers exploring ways to stimulate patients' immune system to attack tumors

Scientists discover new pathway to manipulate, maintain human ESCs in a "na-ve"

Genetics involved with menarche may hold keys to preventing diabetes or osteoporosis in later life

XPro1595 drug can protect vulnerable neurons, reduce motor deficits in Parkinson's model

New textbook on tissue engineering and artificial organ development

New way for development of barley with resistance to powdery mildew

Epigenetic switch can cause cancer, shows study

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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