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Researchers reveal new technique to grow human hepatocytes in the laboratory

In new research appearing in the prestigious journal Nature Biotechnology, an international research team led by The Hebrew University of Jerusalem describes a new technique for growing human hepatocytes in the laboratory. This groundbreaking development could help advance a variety of liver-related research and applications, from studying drug toxicity to creating bio-artificial liver support for patients awaiting transplantations.

27 Nov 2015

Research paves way for clinical trials of cell therapies to treat Parkinson's disease, spinal cord injury

Stem cells that have been specifically developed for use as clinical therapies are fit for use in patients, an independent study of their genetic make-up suggests.

26 Nov 2015

Oxytocin hormone strengthens social ties

Nowadays, much emphasis is placed on sustainability. The degree to which people are willing to donate their own money for this depends on their level of oxytocin. Scientists at the University of Bonn Hospital have discovered that the willingness to donate increases with the quantity of this bonding hormone. However, oxytocin only has an effect with regard to social sustainability projects. The hormone does not increase the ability to participate in the case of purely environmentally oriented projects.

26 Nov 2015

E. coli can move faster and farther in syrup-like fluids than in water, say Penn researchers

Swimming in a pool of syrup would be difficult for most people, but for bacteria like E. coli, it's easier than swimming in water. Scientists have known for decades that these cells move faster and farther in viscoelastic fluids, such as the saliva, mucus, and other bodily fluids they are likely to call home, but didn't understand why.

26 Nov 2015

Researchers use magic-angle-spinning NMR to unveil structure of CAP-Gly protein

A latticework of tiny tubes called microtubules gives your cells their shape and also acts like a railroad track that essential proteins travel on. But if there is a glitch in the connection between train and track, diseases can occur.

26 Nov 2015

Opsin proteins contribute to heat-seeking movement of sperm

In their arduous journey to the egg, sperm "feel" the heat of the fallopian tube and "taste" the chemical signals of the ova. But a new Weizmann Institute of Science study published in Scientific Reports, in Nature, shows that sperm actually make quite a bit of use of sensors that have mainly been known to belong to the visual system.

26 Nov 2015

Novel anticancer agent appears to have greater potency, longer efficacy than irinotecan and topotecan

In the five decades since camptothecin was first isolated from the bark of a tree used in traditional Chinese medicine and identified as a powerful anticancer agent, several thousand chemicals with similar structures and functions have been investigated. And while two of these analog compounds, irinotecan and topotecan, have been approved in the U.S. as treatments for cancer, both are associated with significant shortcomings.

26 Nov 2015

Study: Mother Nature may help lower cholesterol levels in pregnant women

When it comes to effective solutions for lowering cholesterol levels in pregnant women, Mother Nature may know best.

26 Nov 2015

Exploring how absence of ASS1 protein affects sick children may provide a 'lens' on cancer

What can a rare genetic childhood disease teach us about cancer? Dr. Ayelet Erez of the Weizmann Institute of Science's Department of Biological Regulation says: "A single-mutation disease can act as a 'lens.' If we find exactly what malfunctions in the sick child, we can zoom in and understand the role of the same gene among the many genetic changes that accompany cancer."

26 Nov 2015

Research reveals MECP2 Duplication Syndrome can be reversed

The methyl CpG binding protein 2 gene (MECP2) produces a protein of the same name, the level of which is critical for normal brain function. Mutations leading to protein under-expression cause Rett Syndrome while gene duplication causing over-expression lead to MECP2 Duplication Syndrome. Both disorders are severely debilitating childhood neurological diseases.

26 Nov 2015

Key finding aids quest to produce liver cell therapies

Stem cell scientists have made a key find that aids the quest to produce therapies for patients with liver damage.

26 Nov 2015

University of Georgia researchers evaluate potential new strategy to combat drug-resistant diseases

Researchers at the University of Georgia have developed a model for evaluating a potential new strategy in the fight against drug-resistant diseases.

26 Nov 2015

New doctoral thesis reveals potential treatment for stress-induced cardiomyopathy

Stress induced cardiomyopathy after cerebral hemorrhage has been shown to increase the risk of further brain damage. These patients can now be identified by a simple blood test, and a possible treatment for stress induced cardiomyopathy has been discovered - a different kind of anesthesia than that currently being used. A new doctoral thesis at Sahlgrenska Academy has explored these issues.

26 Nov 2015

Researchers successfully combine antibody-drug conjugate with immunotherapy to attack breast cancer cells

To more efficiently treat breast cancer, scientists have been researching molecules that selectively bind to cancer cells and deliver a substance that can kill the tumor cells, for several years. Researchers from the University and University Hospital Basel have now for the first time successfully combined such an antibody-drug conjugate with a therapy that stimulates the immune system to attack tumor cells.

26 Nov 2015

Study points to new avenue for developing potential strategies to thwart HIV virus

Nearly 37 million people worldwide are living with HIV. When the virus destroys so many immune cells that the body can't fight off infection, AIDS will develop. The disease took the lives of more than a million people last year.

26 Nov 2015

Scientists map out genes that keep cancer cells alive

Scientists have mapped out the genes that keep our cells alive, creating a long-awaited foothold for understanding how our genome works and which genes are crucial in disease like cancer.

26 Nov 2015

Bile pigment may provide natural protection from heart attacks

New hope in the fight against cardiovascular disease has arrived, following breakthrough research identifying a pigment in our bile which could protect us.

26 Nov 2015

Researchers aiming to improve accuracy of current diagnostics for Leishmania infantum kinetoplast

In an article published in Small, researchers successfully applied a new qualitative and quantitative method for the detection of a DNA sequence characteristic of Leishmania infantum kinetoplast, a frequent parasite in veterinary that affects humans too.

26 Nov 2015

Purdue researchers develop products and processes to improve detection, treatment of diabetes

Food gatherings at Thanksgiving and Christmas require rigorous management by people affected by diabetes. Type 1 diabetes, also known as juvenile diabetes, is the result of the breakdown of insulin-producing cells in the pancreas. Type 2 diabetes can be the result of a combination of obesity, high caloric intake and a sedentary lifestyle.

26 Nov 2015

TransLUMINAL-B project kicked off to study luminal breast cancers

Following a kick-off meeting, the TransLUMINAL-B project, which is being led by Charité -- Universitätsmedizin Berlin, is now officially underway. Over the next three years, researchers involved in the project will study the process of metastasis formation and the role of malignant cells, which accumulate in the blood and bone marrow of patients with certain types of breast cancer.

26 Nov 2015

Medical Science News

Researchers reveal new technique to grow human hepatocytes in the laboratory

Research paves way for clinical trials of cell therapies to treat Parkinson's disease, spinal cord injury

Oxytocin hormone strengthens social ties

E. coli can move faster and farther in syrup-like fluids than in water, say Penn researchers

Researchers use magic-angle-spinning NMR to unveil structure of CAP-Gly protein

Opsin proteins contribute to heat-seeking movement of sperm

Novel anticancer agent appears to have greater potency, longer efficacy than irinotecan and topotecan

Study: Mother Nature may help lower cholesterol levels in pregnant women

Exploring how absence of ASS1 protein affects sick children may provide a 'lens' on cancer

Research reveals MECP2 Duplication Syndrome can be reversed

Key finding aids quest to produce liver cell therapies

University of Georgia researchers evaluate potential new strategy to combat drug-resistant diseases

New doctoral thesis reveals potential treatment for stress-induced cardiomyopathy

Researchers successfully combine antibody-drug conjugate with immunotherapy to attack breast cancer cells

Study points to new avenue for developing potential strategies to thwart HIV virus

Scientists map out genes that keep cancer cells alive

Bile pigment may provide natural protection from heart attacks

Researchers aiming to improve accuracy of current diagnostics for Leishmania infantum kinetoplast

Purdue researchers develop products and processes to improve detection, treatment of diabetes

TransLUMINAL-B project kicked off to study luminal breast cancers

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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