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Matricellular proteins may be key therapeutic targets for common ocular disorders

A special issue of Journal of Ocular Pharmacology and Therapeutics highlights the latest research on matricellular proteins, which play a critical role in inflammation and blood vessel formation in the eye and therefore making them key targets for new therapies to treat common ocular disorders such as glaucoma, dry eye disease, and age-related macular degeneration (AMD).

23 Sep 2015

New analysis shows rare gene mutations cause half of all ASD cases

A team led by researchers at Cold Spring Harbor Laboratory (CSHL) this week publishes in PNAS a new analysis of data on the genetics of autism spectrum disorder (ASD).

23 Sep 2015

S. Lawrence Zipursky to receive 2015 Louisa Gross Horwitz Prize from Columbia University

Columbia University will award the 2015 Louisa Gross Horwitz Prize to S. Lawrence Zipursky, PhD, for discovering a molecular identification system that helps neurons to navigate and wire the brain. Zipursky is a professor of biological chemistry at the University of California, Los Angeles and a Howard Hughes Medical Institute investigator.

23 Sep 2015

Researchers receive NIH grants to find genomic regions containing variants that affect disease risk

Six new grants from the National Institutes of Health will support researchers to develop new computational approaches for searching among millions of genomic variants to find those that make a difference in disease susceptibility or in other traits.

23 Sep 2015

TSRI scientists awarded grant from Gates Foundation to develop revolutionary alternative HIV/AIDS vaccine

Scientists from the Florida campus of The Scripps Research Institute have been awarded up to nearly $6 million dollars from the Bill & Melinda Gates Foundation to develop a revolutionary HIV/AIDS alternative vaccine that has demonstrated great potential in animal models.

23 Sep 2015

Radboud university medical center reveals how BCG vaccine works against tuberculosis

Not only the acquired immune system but also the innate immune system has a memory. And the BCG vaccine against tuberculosis can stimulate this memory. After a BCG vaccination the innate immune system responds better to a wide range of other infections. Mihai Netea and colleagues from Radboud university medical center discovered and described how that works. They think that the old vaccine could be useful for specific target groups, such as the elderly.

23 Sep 2015

Researchers find potential new way to target brain cells affected by Parkinson's disease

Researchers from Imperial College London and Newcastle University believe they have found a potential new way to target cells of the brain affected by Parkinson's disease.

23 Sep 2015

UNC Lineberger earns 'exceptional' rating from NCI for major grant application

The UNC Lineberger Comprehensive Cancer Center earned an "exceptional" rating from the National Cancer Institute for a major grant application associated with the center's multidisciplinary research.

23 Sep 2015

New gene mutation linked to fatal swelling in unborn and newborn babies

Scientists have discovered a new gene mutation that causes potentially fatal swelling in unborn and newborn babies. Identifying the gene is the first step toward a future diagnostic test and targeted treatment for this condition.

23 Sep 2015

New genetic cause identified for congenital heart arrhythmia

Scientists at The Ohio State University Dorothy M. Davis Heart and Lung Research Institute have identified a new genetic cause for congenital heart arrhythmia. The results of their research are published online by the Proceedings of the National Academy of Sciences (PNAS).

23 Sep 2015

People with specific genotype are more deeply affected by life experiences, reveals study

People with a certain type of gene are more deeply affected by their life experiences, a new study has revealed.

23 Sep 2015

Novel mechanism may help explain the virulence of 1918 'Spanish' flu

While yearly outbreaks of flu kill about 250,000 to 500,000 people worldwide, the 1918 "Spanish" flu infected one-third of the world's population and killed 50 million to 100 million. Chad Petit, Ph.D., assistant professor in the University of Alabama at Birmingham Department of Biochemistry and Molecular Genetics, has discovered a novel mechanism for one 1918 flu virus protein that may help explain the virulence of that unusually deadly pandemic.

23 Sep 2015

TTUHSC El Paso researcher awarded $375,000 grant to develop genetically altered TB vaccines

A $375,000 grant from the Robert J. Kleberg Jr. and Helen C. Kleberg Foundation was awarded to Subramanian Dhandayuthapani, Ph.D., an associate professor in the Center of Emphasis in Infectious Diseases at the Texas Tech University Health Sciences Center El Paso Paul L. Foster School of Medicine, to develop genetically altered vaccines against tuberculosis (TB).

23 Sep 2015

Johns Hopkins scientists discover earliest premalignant genetic changes that mark potential onset of lung cancer

Working with tissue, blood and DNA from six people with precancerous and cancerous lung lesions, a team of Johns Hopkins scientists has identified what it believes are among the very earliest “premalignant” genetic changes that mark the potential onset of the most common and deadliest form of disease.

23 Sep 2015

TSRI study reveals key morphine regulator that may help develop less-addictive pain medications

Once used in the 18th century as currency to reverse the trade imbalance between China and Britain, opiates that contain morphine have been misunderstood almost continually ever since.

23 Sep 2015

UF researchers create fungi database to promote healthier environments

University of Florida Assistant Professor Matthew E. Smith is readying millions of fungi specimens for their close-ups. He and members of his team are helping to take photographs of and catalogue 2.3 million microfungi specimens for a worldwide database of mushrooms, truffles, molds and mildews, among other types of fungi.

23 Sep 2015

Innovative detector could expand use of polarized light for drug screening, surveillance

Invention of the first integrated circularly polarized light detector on a silicon chip opens the door for development of small, portable sensors that could expand the use of polarized light for drug screening, surveillance, optical communications and quantum computing, among other potential applications.

23 Sep 2015

Medical Science News

Matricellular proteins may be key therapeutic targets for common ocular disorders

New analysis shows rare gene mutations cause half of all ASD cases

S. Lawrence Zipursky to receive 2015 Louisa Gross Horwitz Prize from Columbia University

Researchers receive NIH grants to find genomic regions containing variants that affect disease risk

TSRI scientists awarded grant from Gates Foundation to develop revolutionary alternative HIV/AIDS vaccine

Radboud university medical center reveals how BCG vaccine works against tuberculosis

Researchers find potential new way to target brain cells affected by Parkinson's disease

UNC Lineberger earns 'exceptional' rating from NCI for major grant application

New gene mutation linked to fatal swelling in unborn and newborn babies

New genetic cause identified for congenital heart arrhythmia

People with specific genotype are more deeply affected by life experiences, reveals study

Novel mechanism may help explain the virulence of 1918 'Spanish' flu

TTUHSC El Paso researcher awarded $375,000 grant to develop genetically altered TB vaccines

Johns Hopkins scientists discover earliest premalignant genetic changes that mark potential onset of lung cancer

TSRI study reveals key morphine regulator that may help develop less-addictive pain medications

UF researchers create fungi database to promote healthier environments

Innovative detector could expand use of polarized light for drug screening, surveillance

Healthy adults with larger orbitofrontal cortex are more optimistic, less anxious

Reduced conflict-related brain activity linked to higher risk for psychosis

Subtle differences in brain function make women react differently to negative emotions, shows research

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

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