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Manchester scientists treat fatal genetic brain disease using stem cell gene therapy

Scientists from The University of Manchester have used stem cell gene therapy to treat a fatal genetic brain disease in mice for the first time.

From The University of Manchester 25 Jul 2013

STED-RICS microscopy method records rapid movements of molecules in live samples

The newly developed STED-RICS microscopy method records rapid movements of molecules in live samples. By combining raster image correlation spectroscopy (RICS) with STED fluorescence microscopy, researchers of Karlsruhe Institute of Technology (KIT) opened up new applications in medical research, e.g. analyzing the dynamics of cell membranes at high protein concentrations.

25 Jul 2013

Stem cell-based epilepsy approach may help in search for better medicines to treat seizure disorders

A new stem cell-based approach to studying epilepsy has yielded a surprising discovery about what causes one form of the disease, and may help in the search for better medicines to treat all kinds of seizure disorders.

25 Jul 2013

Infants develop fear of heights as a result of their experiences, says study

Infants develop a fear of heights as a result of their experiences moving around their environments, according to new research published in Psychological Science, a journal of the Association for Psychological Science.

25 Jul 2013

NIAID researchers discover monoclonal antibody can neutralize human norovirus

Researchers from the National Institute of Allergy and Infectious Diseases (NIAID) provide the first proof of concept data showing that a monoclonal antibody can neutralize human norovirus. This research, which could one day lead to effective therapies against the virus, was published online ahead of print in the Journal of Virology.

25 Jul 2013

Researchers find that Notch signaling elevated in tumors relative to normal bone

Many cancers show inappropriate activation of a cell signaling pathway called NOTCH. In the developing body, NOTCH tells brain cells to grow and proliferate. It should be quiet in the adult body, but cancers restart NOTCH to drive their own growth, far and beyond the rate of healthy tissues.

25 Jul 2013

Mda-9/syntenin helps regulate bladder cancer growth and metastasis

Scientists from Virginia Commonwealth University Massey Cancer Center have provided evidence from preclinical experiments that a gene known as melanoma differentiation associated gene-9/syntenin (mda-9/syntenin) could be used as a therapeutic target to kill bladder cancer cells, help prevent metastasis and even be used to non-invasively diagnose the disease and monitor its progression.

25 Jul 2013

Study reveals African bats may play a role in evolution of MERS-CoV predecessor viruses

The MERS-coronavirus is regarded as a dangerous novel pathogen: Almost 50 people have died from infection with the virus since it was first discovered in 2012. To date all cases are connected with the Arabian peninsula. Scientists from the University Bonn (Germany) and South Africa have now detected a virus in the faeces of a South African bat that is genetically more closely related to MERS-CoV than any other known virus.

25 Jul 2013

Enzyme in airway lining cells could hold key for asthma sufferers

An enzyme known for its role in heart disease may well be a promising target to treat asthma. Researchers from the University of Iowa have found that the enzyme, called CaMKII, is linked to the harmful effects of oxidation in the respiratory tract, triggering asthmatic symptoms.

25 Jul 2013

Scientists identify new genetic mutations that can cause pulmonary arterial hypertension

Columbia University Medical Center (CUMC) scientists have identified new genetic mutations that can cause pulmonary arterial hypertension (PAH), a rare fatal disease characterized by high blood pressure in the lungs.

25 Jul 2013

Faulty genetic pathway is a potent player in many types of allergies, say researchers

Newly published research by investigators at the Johns Hopkins Children's Center and the Johns Hopkins Institute of Genetic Medicine reveals that a faulty genetic pathway already known for its role in some connective tissue disorders is also a potent player in many types of allergies.

25 Jul 2013

Researcher identify genetic mutation in Africans with HIV that puts them at higher risk for tuberculosis

A researcher from the Perelman School of Medicine at the University of Pennsylvania and colleagues have identified the genetic mutation in Africans with HIV that puts them at a much higher risk for tuberculosis (TB) infections.

25 Jul 2013

OGT offers demo version of Genefficiency NGS Variant Analysis Report software for researchers

Oxford Gene Technology (OGT), provider of innovative genetics research and biomarker solutions to advance molecular medicine, is offering the research community a snapshot of its user-friendly Genefficiency™ NGS Variant Analysis Report software, with the release of a free-to-download demo version.

From Oxford Gene Technology 24 Jul 2013

OracleBio to highlight Oncology image analysis expertise at Tumor Models conference

OracleBio, providers of high precision digital image analysis services for detailed quantification of histological marker staining within cells and tissues, is pleased to announce it will be a principal sponsor of the forthcoming Tumor Models conference to be held in Boston, MA on the 23-25th July.

24 Jul 2013

GSD receives FDA Clearance for 25-OH Vitamin D Total ELISA test

Gold Standard Diagnostics, Corp., a leading manufacturer and marketer of clinical laboratory instrumentation and assays for the in vitro diagnostics market, announced 510k FDA Clearance of its 25-OH Vitamin D, Total ELISA.

24 Jul 2013

Louisiana Tech University to receive NASA EPSCoR grant to support aerospace research

Louisiana Tech University will receive over $1.4 million in grant funding from NASA's Experimental Program to Stimulate Competitive Research, through an award to the Louisiana Board of Regents, to serve as the lead institution for research that investigates how high doses of space radiation during extended duration space missions will affect astronauts.

24 Jul 2013

Inovio plans to advance synthetic hTERT cancer vaccine into clinical trials in 2014

Inovio Pharmaceuticals, Inc. announced today that in a preclinical study with two animal models, Inovio's hTERT (human telomerase reverse transcriptase) DNA cancer vaccine administered with Inovio's CELLECTRA adaptive electroporation delivery technology generated robust and broad immune responses, broke the immune system's tolerance to its self-antigens, induced T-cells with a tumor-killing function, and increased the rate of survival.

24 Jul 2013

Study: Breathing oxygen during radiation therapy can delay tumor growth

A multidisciplinary team at UT Southwestern Medical Center has found that measuring the oxygenation of tumors can be a valuable tool in guiding radiation therapy, opening the door for personalized therapies that keep tumors in check with oxygen enhancement.

24 Jul 2013

Study reveals fungus coating on stored food may worsen AIDS epidemic

A type of fungus coating much of the stored corn, wheat, rice and nuts in developing countries may be quietly worsening the AIDS epidemic, according to a paper published today in the World Mycotoxin Journal.

24 Jul 2013

BGI, CITIC-XIANGYA successfully apply NGS to detect IVF embryos with genetic abnormalities

The largest genomic institute of the world, BGI Shenzhen, China, together with Reproductive & Genetic Hospital CITIC-XIANGYA announced today that they have successfully applied Next Generation Sequencing to detect in vitro fertilized embryos with genetic abnormalities.

24 Jul 2013

Medical Science News

Manchester scientists treat fatal genetic brain disease using stem cell gene therapy

STED-RICS microscopy method records rapid movements of molecules in live samples

Stem cell-based epilepsy approach may help in search for better medicines to treat seizure disorders

Infants develop fear of heights as a result of their experiences, says study

NIAID researchers discover monoclonal antibody can neutralize human norovirus

Researchers find that Notch signaling elevated in tumors relative to normal bone

Mda-9/syntenin helps regulate bladder cancer growth and metastasis

Study reveals African bats may play a role in evolution of MERS-CoV predecessor viruses

Enzyme in airway lining cells could hold key for asthma sufferers

Scientists identify new genetic mutations that can cause pulmonary arterial hypertension

Faulty genetic pathway is a potent player in many types of allergies, say researchers

Researcher identify genetic mutation in Africans with HIV that puts them at higher risk for tuberculosis

OGT offers demo version of Genefficiency NGS Variant Analysis Report software for researchers

OracleBio to highlight Oncology image analysis expertise at Tumor Models conference

GSD receives FDA Clearance for 25-OH Vitamin D Total ELISA test

Louisiana Tech University to receive NASA EPSCoR grant to support aerospace research

Inovio plans to advance synthetic hTERT cancer vaccine into clinical trials in 2014

Study: Breathing oxygen during radiation therapy can delay tumor growth

Study reveals fungus coating on stored food may worsen AIDS epidemic

BGI, CITIC-XIANGYA successfully apply NGS to detect IVF embryos with genetic abnormalities

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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