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Brain's immune cells play direct role in development of amyotrophic lateral sclerosis

Cedars-Sinai research scientists have found that immune cells in the brain play a direct role in the development of amyotrophic lateral sclerosis, or ALS, offering hope for new therapies to target the neurodegenerative disease that gradually leads to paralysis and death.

18 Mar 2016

UT Southwestern researchers identify new role for protein linked to neurological disorders and cancers

Researchers at UT Southwestern Medical Center have identified a second role for a class of RNA-binding proteins, revealing new insights about neurological diseases and conditions associated with this protein such as autism, epilepsy, and certain types of cancer.

18 Mar 2016

UC San Diego researchers use CRISPR-Cas9 system to target RNA in living cells for first time ever

The genetic code stored in DNA determines everything from the color of our eyes to our susceptibility to disease. This has motivated scientists to sequence the human genome and develop ways to alter the genetic code, but many diseases are linked to a different fundamental molecule: RNA.

18 Mar 2016

New scaffold technology could someday help treat Parkinson's disease, other brain-related conditions

Scientists at Rutgers and Stanford universities have created a new technology that could someday help treat Parkinson's disease and other devastating brain-related conditions that affect millions of people.

18 Mar 2016

Genomic profiling could help provide targeted therapies for difficult to treat cancer tumors

Research from Rutgers Cancer Institute of New Jersey examining difficult to treat cancer tumors through genomic profiling shows that tumors with alterations in a signaling pathway responsible for cell regulation may respond to targeted therapy regardless of where the tumor originated in the body.

18 Mar 2016

Sodium MRI could provide more detailed picture of tissue health and disease

MRI experts at The University of Nottingham win £1m grant to adapt scanning techniques to pick up sodium in the body. The research could lead to much more detailed MRI scans in the future with significant improvements to the diagnosis and treatment of many diseases.

18 Mar 2016

Study sheds light on role of RNA editing in cancer

A new study provides insight on the potential role played by RNA (ribonucleic acid) editing in cancer. The findings, which appear online in the journal Scientific Reports, may further our understanding of an emerging mechanism implicated in tumor initiation and progression, and may thus lead to the development of better treatment options in the future.

18 Mar 2016

New study provides insight into working memory

When you hold in mind a sentence you have just read or a phone number you're about to dial, you're engaging a critical brain system known as working memory.

18 Mar 2016

UW-Madison neuroscientist discover genetic machinery that causes maturation in young nerve cells

In one of the first studies to 'read' the genetic activity inside individual brain cells, University of Wisconsin-Madison neuroscientist Xinyu Zhao has identified the genetic machinery that causes maturation in a young nerve cell. The cells under study came from the hippocampus, a memory-related structure that is the only place in a mammal's brain where new neurons can form throughout life.

18 Mar 2016

Treatment guidelines need to be changed for rare, genetic form of diabetes, study suggests

Patients with a rare, genetic form of diabetes often are misdiagnosed as having type 2 diabetes because the two share symptoms.

18 Mar 2016

Neo-Bioscore staging system adds HER2 status for precise prognostic stratification of breast cancer subtypes

A new breast cancer staging system developed by researchers at The University of Texas MD Anderson Cancer Center finds that incorporating tumor biology is a critical prognostic indicator for women who undergo neoadjuvant, or pre-surgical, therapy for breast cancer.

18 Mar 2016

CIRM approves $6.3 million grant to support research on novel stem cell-based therapy for ALS

The Independent Citizens Oversight Committee of the California Institute for Regenerative Medicine approved yesterday a $6.3 million grant to a research team from the University of California, San Diego School of Medicine and University of California, Davis to pursue a novel human embryonic stem cell-based therapy to rescue and restore neurons devastated by amyotrophic lateral sclerosis or ALS.

18 Mar 2016

Inhibiting cholesterol esterification can potentiate antitumor activity of killer T cells

As key players in the immune system, T cells provide tumor surveillance and have direct antitumor effects. However, tumors can escape T-cell attack through various mechanisms in the tumor microenvironment. Reactivating the antitumor effects of T cells has shown great clinical benefits in treating various cancers.

18 Mar 2016

EPFL scientists develop cutting-edge treatment for Alzheimer's disease

In a cutting-edge treatment for Alzheimer's disease, EPFL scientists have developed an implantable capsule that can turn the patient's immune system against the disease.

18 Mar 2016

UNIGE researchers identify new recessive disease

The objective of genetic medicine is to analyze all the genes that make up the human genome, in order to identify as many genetic diseases as possible. Indeed, each gene variation has the potential to trigger specific defects. Among all genetic conditions, diseases known as "recessive" occur only when both the father and the mother are healthy carriers of the same defective gene which can be passed down to their children.

18 Mar 2016

New 3D micro-scaffold technology promotes reprogramming of stem cells into neurons

National Institutes of Health-funded scientists have developed a 3D micro-scaffold technology that promotes reprogramming of stem cells into neurons, and supports growth of neuronal connections capable of transmitting electrical signals.

18 Mar 2016

New subtype of bladder cancer shares molecular signatures with breast cancer

Bladder cancer is the fourth most common cancer among men in the United States. While low-grade tumors have a very favorable prognosis, muscle-invasive and metastatic tumors have poorer survival rates.

17 Mar 2016

Unhealthy diet, lack of exercise speed up onset of age-related conditions in mice

Could an unhealthy diet and lack of exercise be making you age faster? Researchers at Mayo Clinic believe there is a link between these modifiable lifestyle factors and the biological processes of aging. In a recent study, researchers demonstrated that a poor diet and lack of exercise accelerated the onset of cellular senescence and, in turn, age-related conditions in mice.

17 Mar 2016

Mothers give offspring a head start in life

Thank your mothers: A research collaboration between UC Santa Barbara and L'École Normale Supérieure in Paris has proven that deterministic maternal effects can give offspring a better start on life.

17 Mar 2016

Automated techniques could dramatically accelerate antimicrobial discovery

The antimicrobial arsenal that we count on to save millions of lives each year is alarmingly thin--and these microbes are rapidly evolving resistance to our weapons. But help may be on the way: In a study posted in the AMB Express, researchers from the National Institute of Standards and Technology show that automated techniques commonly used to screen new drugs for mammalian cell toxicity could also dramatically speed up the challenging task of antimicrobial discovery.

17 Mar 2016

Medical Science News

Brain's immune cells play direct role in development of amyotrophic lateral sclerosis

UT Southwestern researchers identify new role for protein linked to neurological disorders and cancers

UC San Diego researchers use CRISPR-Cas9 system to target RNA in living cells for first time ever

New scaffold technology could someday help treat Parkinson's disease, other brain-related conditions

Genomic profiling could help provide targeted therapies for difficult to treat cancer tumors

Sodium MRI could provide more detailed picture of tissue health and disease

Study sheds light on role of RNA editing in cancer

New study provides insight into working memory

UW-Madison neuroscientist discover genetic machinery that causes maturation in young nerve cells

Treatment guidelines need to be changed for rare, genetic form of diabetes, study suggests

Neo-Bioscore staging system adds HER2 status for precise prognostic stratification of breast cancer subtypes

CIRM approves $6.3 million grant to support research on novel stem cell-based therapy for ALS

Inhibiting cholesterol esterification can potentiate antitumor activity of killer T cells

EPFL scientists develop cutting-edge treatment for Alzheimer's disease

UNIGE researchers identify new recessive disease

New 3D micro-scaffold technology promotes reprogramming of stem cells into neurons

New subtype of bladder cancer shares molecular signatures with breast cancer

Unhealthy diet, lack of exercise speed up onset of age-related conditions in mice

Mothers give offspring a head start in life

Automated techniques could dramatically accelerate antimicrobial discovery

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

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