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Study shows over-expression of adhesion molecules in fat tissues protects mice from obesity, diabetes

Okayama University researchers report that the overexpression of an adhesion molecule found on the surface of fat cells appears to protect mice from developing obesity and diabetes. The findings, published in the journal Diabetes, March 2016, may fuel the development of new therapies targeting these diseases.

9 May 2016

Food deprivation may help treat fatty liver disease

Scientists at Helmholtz Zentrum München have new information on what happens at the molecular level when we go hungry. Working with the Deutsches Zentrum für Diabetesforschung and the Deutsches Krebsforschungszentrum they were able to show that upon deprivation of food a certain protein is produced that adjusts the metabolism in the liver.

9 May 2016

Research shows spleen MZ B cells produce signaling proteins involved in inflammatory responses

The inability to adequately respond to infection can cause a whole-body state of inflammation known as sepsis. This can eventually lead to systemic inflammatory response syndrome (SIRS), and even death.

9 May 2016

Scientists develop new technology that helps visualize translation of mRNA into proteins

For the first time, scientists at Albert Einstein College of Medicine have developed a technology allowing them to "see" single molecules of messenger RNA as they are translated into proteins in living mammalian cells. Initial findings using this technology that may shed light on neurological diseases as well as cancer were published online today in Science.

9 May 2016

Study highlights significance of tiny RNA molecules in tissue regeneration process

Dr. Elizabeth Hutchins, a Post-Doctoral Fellow in TGen's Neurogenomics Division, and co-lead author of the study, said she hopes this investigation eventually enables such things as regenerating cartilage in knees, repairing spinal cords in accident victims, and reproducing the muscles of injured war veterans.

9 May 2016

Study hints at new therapeutic approach to mitigate effects of prenatal Zika virus infection

The U.S. Centers for Disease Control and Prevention recently concluded that Zika virus infection in pregnant women can stunt neonatal brain development, leading to babies born with abnormally small heads, a condition known as microcephaly. Now, for the first time, researchers at University of California San Diego School of Medicine have determined one way Zika infection can damage developing brain cells.

9 May 2016

Researchers find way to selectively deliver drugs to placenta without harming fetus

Nearly 10 percent of babies born in the United States are born premature, according to the March of Dimes. The underlying cause of many complications during pregnancy is often a poorly functioning placenta, the organ that nourishes and maintains the fetus.

9 May 2016

Unique attributes of zebrafish may help study human blood disorders

Genetic regulation of the various types of blood cells in zebrafish and humans is highly similar, making it relatively easy and cost-effective to perform genetic, chemical, imaging and other molecular studies on this invaluable model organism to study normal hematopoetic development in humans as well as blood disorders and malignancies, as described in a Review article in Human Gene Therapy, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

9 May 2016

Minihepcidins may potentially treat serious genetic blood diseases in children, adults

New research suggests that synthetic peptides called minihepcidins may potentially treat two serious genetic blood diseases in children and adults. Although those diseases, beta-thalassemia and polycythemia vera, have opposite effects on red blood cell production, treating animals with minihepcidin helps to restore normal levels of red blood cells and reduces spleen enlargement. It also controls the accumulation of excess levels of iron in beta-thalassemia that often causes severe toxic effects.

9 May 2016

Researchers investigate effects of new steroid treatment on children with ARDS

Acute Respiratory Distress Syndrome (ARDS) affects hundreds of thousands of people each year, many of them children. Those with this life threatening condition have severely injured and wet lungs, and are treated with mechanical ventilation.

9 May 2016

New antibody-based therapy may provide better strategy for long-term control of HIV

The development of antiretroviral therapy, a combination of drugs that slows the replication of HIV in the body, has transformed the treatment of this infection. What was once a certain death sentence is now a chronic condition that people can live with for decades.

9 May 2016

UV clothing can give better sunblock

Just as most people know there is no such thing as safe smoking, there is also no such thing as safe sunbathing or tanning. Exposure to UVA and UVB rays can cause more than just a sunburn or tan - it can lead to everything from wrinkles to skin cancer.

8 May 2016

Reasons for life-threatening blood clots in elite athletes

Mary Cushman, M.D., M.Sc., a professor of medicine and director of the Thrombosis and Hemostasis Program at the University of Vermont, provides commentary on the causes of life-threatening blood clots in elite athletes.

6 May 2016

Wolff-Parkinson-White patients continue to have atrial fibrillation risk even after catheter ablation, study finds

Patients with Wolff-Parkinson-White syndrome who receive catheter ablation to cure their abnormal heart rhythms are just as likely as non-ablated patients to develop atrial fibrillation no matter what age they receive ablation, according to a new study.

6 May 2016

Genetic variations that prevent beneficial gut bacteria from working may lead to Crohn's disease

A major type of inflammatory bowel disease (IBD) may be caused in part by genetic variants that prevent beneficial bacteria in the gut from doing their job, according to a new study published today in the journal Science.

6 May 2016

Serum biomarkers can help predict risk of IBD development and complications

Years before inflammatory bowel disease (IBD) is diagnosed and symptoms exist, biomarkers are already circulating that can help predict risk not only of disease development but also of complications, according to research published online last week, which will also appear in the June 15th print issue of Alimentary Pharmacology & Therapeutics.

6 May 2016

Importance of understanding ovarian cancer on molecular level

Nearly 70 percent of ovarian cancer cases are detected after metastasis, which is the development of secondary malignant growths distant from the primary site of cancer.

6 May 2016

Novel animal model helps understand mechanisms that lead to multiple myeloma

Researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have developed an animal model that allows them to better understand the mechanisms that lead to the development of multiple myeloma, a hematologic cancer of plasma cells, and the amyloidosis that sometimes accompanies it. The study was published in the journal Scientific Reports.

6 May 2016

Implication of microRNAs in cancer development greater than previously thought

Small, non-coding molecules called microRNAs are known to play an important role in cancer development. Researchers now have shown their significance is greater than previously thought, a finding that could lead to new therapeutic approaches for the most common and deadly form of ovarian cancer.

6 May 2016

Key protein involved in mitosis helps prevent abnormal distribution of chromosomes

A tension-sensitive "fail safe" protein helps make sure that when our cells divide the two resulting cells inherit the normal number of chromosomes, researchers from the University of Washington and the Fred Hutchinson Cancer Research Center report today, May 5, in the journal Cell.

6 May 2016

Medical Science News

Study shows over-expression of adhesion molecules in fat tissues protects mice from obesity, diabetes

Food deprivation may help treat fatty liver disease

Research shows spleen MZ B cells produce signaling proteins involved in inflammatory responses

Scientists develop new technology that helps visualize translation of mRNA into proteins

Study highlights significance of tiny RNA molecules in tissue regeneration process

Study hints at new therapeutic approach to mitigate effects of prenatal Zika virus infection

Researchers find way to selectively deliver drugs to placenta without harming fetus

Unique attributes of zebrafish may help study human blood disorders

Minihepcidins may potentially treat serious genetic blood diseases in children, adults

Researchers investigate effects of new steroid treatment on children with ARDS

New antibody-based therapy may provide better strategy for long-term control of HIV

UV clothing can give better sunblock

Reasons for life-threatening blood clots in elite athletes

Wolff-Parkinson-White patients continue to have atrial fibrillation risk even after catheter ablation, study finds

Genetic variations that prevent beneficial gut bacteria from working may lead to Crohn's disease

Serum biomarkers can help predict risk of IBD development and complications

Importance of understanding ovarian cancer on molecular level

Novel animal model helps understand mechanisms that lead to multiple myeloma

Implication of microRNAs in cancer development greater than previously thought

Key protein involved in mitosis helps prevent abnormal distribution of chromosomes

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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