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Malvern launches two new ITC systems to support life science research

Malvern Instruments has launched two new-generation isothermal titration calorimeters (ITC), advancing its recently acquired MicroCal range to further support life science researchers studying biomolecular interactions. The new manual Malvern MicroCal PEAQ-ITC and fully automated Malvern MicroCal PEAQ-ITC Automatedsystems are designed to deliver the enhanced functionality and robust performance now demanded of this essential tool.

3 Mar 2015

TSRI researchers show how ABC transporters cause multidrug resistance

Cancer patients fear the possibility that one day their cells might start rendering many different chemotherapy regimens ineffective. This phenomenon, called multidrug resistance, leads to tumors that defy treatment.

3 Mar 2015

MD Anderson scientists show why some brain cancer patients develop resistance to treatments

Scientists at The University of Texas MD Anderson Cancer Center may have discovered why some brain cancer patients develop resistance to standard treatments including radiation and the chemotherapy agent temozolomide.

3 Mar 2015

Scientists find gorilla origins in two human AIDS virus lineages

Two of the four known groups of human AIDS viruses (HIV-1 groups O and P) have originated in western lowland gorillas, according to an international team of scientists from the Perelman School of Medicine at the University of Pennsylvania, the University of Montpellier, the University of Edinburgh, and others.

3 Mar 2015

SCIEX and Labor Berlin Collaboration to Advance Forensic Testing

SCIEX announced today a research collaboration with Labor Berlin, the largest clinical laboratory in Germany, for the development of a hybrid Quadrupole Time-of-Flight (TOF) MS/MS reference library of relevant forensic chemical compounds

3 Mar 2015

Existing drug could help treat MS, other neurological diseases

Damage to myelin, the fatty insulator that enables communication between nerve cells, characterizes multiple sclerosis (MS) and other devastating neurological diseases.

3 Mar 2015

Texas Tech University professor receives CPRIT grants to study movement of tumor cells

Siva Vanapalli, an associate professor in the Department of Chemical Engineering, at Texas Tech University, recently received two grants from the Cancer Prevention and Research Institute of Texas to study the movement of tumor cells throughout the body and new methods of detecting cancer cells.

3 Mar 2015

CHOPS syndrome sheds light on key biological processes during human development

Analyzing a puzzling multisystem disorder in three children, genetic experts have identified a new syndrome, shedding light on key biological processes during human development. The research also provides important information to help caregivers manage the disorder, and may offer clues to eventually treating it.

3 Mar 2015

Researchers reveal how bacterial molecule controls the body's response to TB infection

The cascade of events leading to bacterial infection and the immune response is mostly understood. However, the molecular mechanisms underlying the immune response to the bacteria that causes tuberculosis have remained a mystery — until now. Researchers at the Johns Hopkins University School of Medicine have now uncovered how a bacterial molecule controls the body's response to TB infection and suggest that adjusting the level of this of this molecule may be a new way to treat the disease.

3 Mar 2015

TREM2 protein may help slow progression of multiple sclerosis, Alzheimer's disease

Highlighting a potential target in the treatment of multiple sclerosis (MS) and Alzheimer's disease, new research suggests that triggering a protein found on the surface of brain cells may help slow the progression of these and other neurological diseases.

3 Mar 2015

MIT researchers develop new nanodevice that can help overcome drug resistance

Chemotherapy often shrinks tumors at first, but as cancer cells become resistant to drug treatment, tumors can grow back. A new nanodevice developed by MIT researchers can help overcome that by first blocking the gene that confers drug resistance, then launching a new chemotherapy attack against the disarmed tumors.

3 Mar 2015

BUSM researchers discover genes involved in formation of lung tumors

The lung transcription factor Nkx2-1 is an important gene regulating lung formation and normal respiratory functions after birth. Alterations in the expression of this transcription factor can lead to diseases such as lung interstitial disease, post-natal respiratory distress and lung cancer.

3 Mar 2015

Caltech researchers reveal new information that could help fight against hookworms

Tiny parasitic hookworms infect nearly half a billion people worldwide--almost exclusively in developing countries--causing health problems ranging from gastrointestinal issues to cognitive impairment and stunted growth in children. By sequencing and analyzing the genome of one particular hookworm species, Caltech researchers have uncovered new information that could aid the fight against these parasites.

3 Mar 2015

People prone to high anxiety make bad decisions under uncertainties of life

Highly anxious people have more trouble deciding how best to handle life's uncertainties. They may even catastrophize, interpreting, say, a lovers' tiff as a doomed relationship or a workplace change as a career threat.

3 Mar 2015

Scientists sequence genome of hookworm

In an advance that may potentially lead to new treatments for parasitic hookworms, scientists at the University of Massachusetts Medical School and Cornell University have sequenced the genome of the hookworm, Ancylostoma ceylanicum.

3 Mar 2015

Data provides better understanding of genetic activity during lung cancer development

Scientists at the University of Granada, incollaboration with the universities of Harvard and Yale (United States) have provided new data for a better understanding of the alterations produced during the development of lung cancer, the tumour with the highest yearly death rate in Spain.

3 Mar 2015

Sall4 protein helps fix DNA damage

A protein that helps embryonic stem cells (ESCs) retain their identity also promotes DNA repair, according to a study in The Journal of Cell Biology. The findings raise the possibility that the protein, Sall4, performs a similar role in cancer cells, helping them fix DNA damage to survive chemotherapy.

3 Mar 2015

Toning down TREM2 receptor's activity may help prevent neurodegeneration in AD patients

Tackling brain inflammation ameliorates Alzheimer's disease (AD), according to a study published in The Journal of Experimental Medicine.

3 Mar 2015

Higher intake of lycopene may lower risk of renal cell carcinoma in postmenopausal women

A higher intake by postmenopausal women of the natural antioxidant lycopene, found in foods like tomatoes, watermelon and papaya, may lower the risk of renal cell carcinoma, a type of kidney cancer.

2 Mar 2015

New genetic discovery may lead to effective treatments for Huntington's disease

A new genetic discovery in the field of Huntington's disease (HD) could mean a more effective way in determining severity of this neurological disease when using specific treatments. This study may provide insight for treatments that would be effective in slowing down or postponing the death of neurons for people who carry the HD gene mutation, but who do not yet show symptoms of the disease.

2 Mar 2015

Medical Science News

Malvern launches two new ITC systems to support life science research

TSRI researchers show how ABC transporters cause multidrug resistance

MD Anderson scientists show why some brain cancer patients develop resistance to treatments

Scientists find gorilla origins in two human AIDS virus lineages

SCIEX and Labor Berlin Collaboration to Advance Forensic Testing

Existing drug could help treat MS, other neurological diseases

Texas Tech University professor receives CPRIT grants to study movement of tumor cells

CHOPS syndrome sheds light on key biological processes during human development

Researchers reveal how bacterial molecule controls the body's response to TB infection

TREM2 protein may help slow progression of multiple sclerosis, Alzheimer's disease

MIT researchers develop new nanodevice that can help overcome drug resistance

BUSM researchers discover genes involved in formation of lung tumors

Caltech researchers reveal new information that could help fight against hookworms

People prone to high anxiety make bad decisions under uncertainties of life

Scientists sequence genome of hookworm

Data provides better understanding of genetic activity during lung cancer development

Sall4 protein helps fix DNA damage

Toning down TREM2 receptor's activity may help prevent neurodegeneration in AD patients

Higher intake of lycopene may lower risk of renal cell carcinoma in postmenopausal women

New genetic discovery may lead to effective treatments for Huntington's disease

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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