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Study identifies genetic variants linked to Hirschsprung’s disease

Genetic studies in humans, zebrafish and mice have revealed how two different types of genetic variations team up to cause a rare condition called Hirschsprung’s disease. The findings add to an increasingly clear picture of how flaws in early nerve development lead to poor colon function, which must often be surgically corrected.

8 Apr 2015

Brain's primary visual cortex can drive the timing of actions

When managing, assigning each task to a specialist is often the most efficient strategy. Most researchers regard the brain as working similarly, with each region specialized to a given task. But Johns Hopkins neuroscientists have found, in rats, that the brain's primary visual cortex (VC) not only portrays the visual world but can also drive the timing of actions.

8 Apr 2015

New blood test may more accurately identify biomarkers for Parkinson's disease

A new blood test may more accurately identify blood signatures, or biomarkers, for Parkinson's disease (PD), according to a new study published in the journal Movement Disorders.

7 Apr 2015

CXCR3 molecule is key mediator of melanoma metastasis, shows research

In a unique partnership demonstrating excellence in "team science," Dartmouth investigators from Norris Cotton Cancer Center identified a role for the molecule CXCR3 (widely known to regulate the migration of immune cells) as a key mediator of melanoma metastasis.

7 Apr 2015

RNA could be a potential target for new anticancer drugs, say UC Berkeley scientists

Most of today's anticancer drugs target the DNA or proteins in tumor cells, but a new discovery by University of California, Berkeley, scientists unveils a whole new set of potential targets: the RNA intermediaries between DNA and proteins.

7 Apr 2015

Study: Key signaling pathway in B-cell lymphoma can be blocked using compounds

Cancer researchers from the University of Zurich have identified a key signaling pathway in B-cell lymphoma, a malignant type of blood cancer.

7 Apr 2015

Common cancers deform mitochondria to create conducive environment for tumor growth

In a breakthrough in the understanding of how cancer does its deadly work, researchers at the University of Virginia School of Medicine have shown that many cancers - including nearly all pancreatic cancers - enslave and deform mitochondria, the powerhouses of cells, to create an environment more conducive to tumor growth.

7 Apr 2015

Arvinas, Merck team up to create new therapeutics using protein degradation technology

Arvinas LLC, a private biotechnology company creating a new class of drugs based on protein degradation, announced a strategic collaboration with Merck, known as MSD outside of the United States and Canada, in which Arvinas' novel PROTAC technology will be used to degrade target proteins, with the goal of creating novel therapeutics.

7 Apr 2015

Combination of pomegranate juice and dates protects against heart disease

Glorious, red pomegranates and their Middle Eastern sister, luscious toffee-like dates, are delicious, increasingly trendy, and healthy to boot.

7 Apr 2015

MGH investigators identify inflammatory molecule that plays key role in lupus

Massachusetts General Hospital (MGH) investigators have identified an inflammatory molecule that appears to play an essential role in the autoimmune disorder systemic lupus erythematosus, commonly known as lupus.

7 Apr 2015

Watching the blood flow

Optical microangiography (OMAG), a technique based on optical coherence tomography, can be used to visualize the microvasculature network under inflamed skin condition. It opens up new vistas for clinical trials of treatment and diagnosis of inflammatory skin disorders.

7 Apr 2015

DreaMed Diabetes and Medtronic enter strategic collaboration

DreaMed Diabetes, developer of diabetes treatment and management solutions, announced today that it had signed an exclusive worldwide development and license agreement with Medtronic, the world's premier medical technology and services company, for the development and marketing of products incorporating DreaMed’s MD-Logic Artificial Pancreas algorithm in Medtronic’s insulin pumps.

From Medtronic 7 Apr 2015

Scientists discover molecular switch that ‘turns off’ HCMV

Human cytomegalovirus (HCMV) is an extremely common virus, which as other members of the herpes virus family causes life-long infections in humans. Most individuals are exposed to HCMV during childhood, yet symptoms can be easily fought off by a healthy immune system.

7 Apr 2015

Study: Broken communication in brain regions appears to worsen Huntington's disease

Indiana University researchers have found that broken communication in a specific part of the brain plays a role in the involuntary physical movements that affect individuals with Huntington's disease.

7 Apr 2015

Scientists identify rhinovirus C receptor associated with severe asthma attacks

Scientists funded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, have identified a cellular receptor for rhinovirus C, a cold-causing virus that is strongly associated with severe asthma attacks.

6 Apr 2015

Healthy eating, exercise, and brain-training programme results in slower mental decline for older people

1260 people from across Finland, aged 60–77 years, were included in the study, with half randomly allocated to the intervention group, and half allocated to a control group, who received regular health advice only. All of the study participants were deemed to be at risk of dementia, based on standardised test scores.

6 Apr 2015

Babies with clinically suspected serious infections can be safely and effectively treated outside hospital

About 1 in 5 babies worldwide develop severe bacterial infections during the first month of life. These infections are responsible for around 700000 deaths in newborns every year...

6 Apr 2015

High Throughput ChIP Sequencing

Chromatrap®, a business unit of Porvair Sciences, has announced a major product launch at the European Human Genetics Conference (Glasgow, UK) and the Festival of Genomics (Boston, USA) on the 6th June 2015 and 22nd-24th June 2015 respectively

From Chromatrap® - Porvair Sciences Ltd 6 Apr 2015

Study reveals how cell's protein quality control mechanism helps combat neurodegenerative diseases

A molecular pathway known to suppress tumors appears to also be a major player in clearing cells of damaged proteins implicated in neurodegenerative diseases such as ALS and certain types of dementia, new research in roundworms and human cells suggests.

6 Apr 2015

Researchers identify 22 genetic variations associated with increased risk of prostate cancer

Prostate cancer affects one out of every 6 men during their lifetime and is the second most common cause of cancer-related death for men in the United States, resulting in an estimated 27,500 deaths in 2015. Identifying those men who have a higher risk of developing prostate cancer may reduce mortality.

6 Apr 2015

Medical Science News

Study identifies genetic variants linked to Hirschsprung’s disease

Brain's primary visual cortex can drive the timing of actions

New blood test may more accurately identify biomarkers for Parkinson's disease

CXCR3 molecule is key mediator of melanoma metastasis, shows research

RNA could be a potential target for new anticancer drugs, say UC Berkeley scientists

Study: Key signaling pathway in B-cell lymphoma can be blocked using compounds

Common cancers deform mitochondria to create conducive environment for tumor growth

Arvinas, Merck team up to create new therapeutics using protein degradation technology

Combination of pomegranate juice and dates protects against heart disease

MGH investigators identify inflammatory molecule that plays key role in lupus

Watching the blood flow

DreaMed Diabetes and Medtronic enter strategic collaboration

Scientists discover molecular switch that ‘turns off’ HCMV

Study: Broken communication in brain regions appears to worsen Huntington's disease

Scientists identify rhinovirus C receptor associated with severe asthma attacks

Healthy eating, exercise, and brain-training programme results in slower mental decline for older people

Babies with clinically suspected serious infections can be safely and effectively treated outside hospital

High Throughput ChIP Sequencing

Study reveals how cell's protein quality control mechanism helps combat neurodegenerative diseases

Researchers identify 22 genetic variations associated with increased risk of prostate cancer

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

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