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Bayer HealthCare and German Cancer Research Center to extend strategic alliance in search of novel cancer therapeutics

Bayer HealthCare (Bayer) and the German Cancer Research Center (DKFZ) will extend their successful strategic research alliance in search of novel cancer therapeutics by focusing their activities also on the field of immunotherapy. Immunotherapies are a promising approach to treat cancer with the aim to selectively reactivate the body's own immune system so that it attacks tumor cells.

10 Apr 2013

Findings could help develop new ways to predict risks of tobacco-associated cancers

Believe it or not, while researchers have explored which genes are mutated in each type of tobacco-associated cancer, until now no one had thought to look across these types for common genes that might predict patient outcomes. Results presented at the AACR Annual Meeting 2013 show that in lung and bladder cancers, genes related to the regulation of the cell cycle are associated with poor patient outcomes.

10 Apr 2013

Gene variations can predispose people to chemotherapy-induced peripheral neuropathy

Seemingly benign differences in genetic code from one person to the next could influence who develops side effects to chemotherapy, a Mayo Clinic study has found.

10 Apr 2013

Multiple genes strongly contribute to risk for schizophrenia

Multiple genes contribute to risk for schizophrenia and appear to function in pathways related to transmission of signals in the brain and immunity, according to an international study led by Virginia Commonwealth University School of Pharmacy researchers.

10 Apr 2013

Research sheds light on malaria-related parasite's transition from acute to chronic stage

A new discovery about the malaria-related parasite Toxoplasma gondii -- which can threaten babies, AIDS patients, the elderly and others with weakened immune function -- may help solve the mystery of how this single-celled parasite establishes life-long infections in people.

10 Apr 2013

BRCA2 gene mutation carriers at greater risk for more advanced prostate cancer

Patients with prostate cancer and hereditary mutations in the BRCA2 gene have a worse prognosis and lower survival rates than do the rest of the patients with the disease.

10 Apr 2013

Mother's stress associated with development of pathologies related with obesity

The intrauterine environment plays an important role in the health of the offspring. Now, experts from the University of Navarra affirm that the mother's stress, due to socio-economic or psycho-social causes, is associated with the development of pathologies related with obesity.

10 Apr 2013

New immunotherapies are seldom developed for childhood cancer

More often than not, cancer immunotherapies that work in adults are used in modified ways in children. Seldom are new therapies developed just for children, primarily because of the small number of pediatric patients relative to the adult cancer patient population.

9 Apr 2013

Researchers develop predictive biomarker to identify cancer patients who may respond to autophagy inhibitors

Autophagy, the process by which cells that are starved for food resort to chewing up their own damaged proteins and membranes and recycling them into fuel, has emerged as a key pathway that cancer cells use to survive in the face of assault by chemotherapy and radiation.

9 Apr 2013

fMRI: A non-invasive tool to map critical areas of brain before surgery

A new functional magnetic resonance imaging (fMRI) technique may provide neurosurgeons with a non-invasive tool to help in mapping critical areas of the brain before surgery, reports a study in the April issue of Neurosurgery, official journal of the Congress of Neurological Surgeons.

9 Apr 2013

UCSB researchers examine role played by Rhs proteins in bacterial intercellular competition

There's an epic battle taking place that's not on the national radar: intercellular competition. While it's not an Olympic event, new research from UC Santa Barbara demonstrates that this microscopic rivalry can be just as fierce as humans going for the gold.

9 Apr 2013

Research: ACOT7 enzyme keeps neurons' fat levels under control

We're all fatheads. That is, our brain cells are packed with fat molecules, more of them than almost any other cell type. Still, if the brain cells' fat content gets too high, they'll be in trouble. In a recent study in mice, researchers at Johns Hopkins pinpointed an enzyme that keeps neurons' fat levels under control, and may be implicated in human neurological diseases.

9 Apr 2013

Researchers design drug to block incidence of head, neck cancer caused by HPV virus

Researchers have discovered a new mechanism by which the human papilloma virus (HPV) causes head and neck cancer, and they have designed a drug to block that mechanism. Though further research is needed, the new agent might offer a safer treatment for these tumors when combined with a tapered dose of standard chemotherapy.

9 Apr 2013

Newly discovered mouse viruses can pave the way for future progress in hepatitis research

Newly discovered mouse viruses could pave the way for future progress in hepatitis research, enabling scientists to study human disease and vaccines in the ultimate lab animal.

9 Apr 2013

Genes for blood vessel growth in retina are "switched on" by SRF protein

Normal functioning of the eye depends on a proper supply of blood to the retina. Light entering the eye passes through the cornea, the lens, and the vitreous body before reaching the retina, where it stimulates the nerves.

9 Apr 2013

Study shows genetics could play a role in exercise motivation

Studies show 97 percent of American adults get less than 30 minutes of exercise a day, which is the minimum recommended amount based on federal guidelines. New research from the University of Missouri suggests certain genetic traits may predispose people to being more or less motivated to exercise and remain active.

9 Apr 2013

UT professor earns INNOVATOR Award for Cancer Prevention Research at AACR meeting 2013

A proposal to examine the cellular journey from normal skin, to precancerous lesion to skin cancer earned Kenneth Tsai, M.D., Ph.D., the Sixth Annual Landon Foundation-AACR INNOVATOR Award for Cancer Prevention Research at the AACR Annual Meeting 2013 in Washington, D.C., April 6-10.

9 Apr 2013

Nano-sized EVs play role in cancer growth and survival

The recent discovery of circulating "nano-sized extracellular vesicles" (EVs) carrying proteins and nucleic acids derived from brain tumors may lead to exciting new avenues for brain cancer diagnosis, monitoring, and treatment, according to a special article in the April issue of Neurosurgery, official journal of the Congress of Neurological Surgeons.

9 Apr 2013

Study: Chicken-killing virus is a promising treatment for prostate cancer

A study at the Virginia-Maryland Regional College of Veterinary Medicine has identified a chicken-killing virus as a promising treatment for prostate cancer in humans.

9 Apr 2013

University of Leicester to launch new research centre to explore complex traits and disease

This week, the University of Leicester launches a new Centre for Genetic Architecture of Complex Traits to explore the building blocks of complex traits and disease.

9 Apr 2013

Medical Science News

Bayer HealthCare and German Cancer Research Center to extend strategic alliance in search of novel cancer therapeutics

Findings could help develop new ways to predict risks of tobacco-associated cancers

Gene variations can predispose people to chemotherapy-induced peripheral neuropathy

Multiple genes strongly contribute to risk for schizophrenia

Research sheds light on malaria-related parasite's transition from acute to chronic stage

BRCA2 gene mutation carriers at greater risk for more advanced prostate cancer

Mother's stress associated with development of pathologies related with obesity

New immunotherapies are seldom developed for childhood cancer

Researchers develop predictive biomarker to identify cancer patients who may respond to autophagy inhibitors

fMRI: A non-invasive tool to map critical areas of brain before surgery

UCSB researchers examine role played by Rhs proteins in bacterial intercellular competition

Research: ACOT7 enzyme keeps neurons' fat levels under control

Researchers design drug to block incidence of head, neck cancer caused by HPV virus

Newly discovered mouse viruses can pave the way for future progress in hepatitis research

Genes for blood vessel growth in retina are "switched on" by SRF protein

Study shows genetics could play a role in exercise motivation

UT professor earns INNOVATOR Award for Cancer Prevention Research at AACR meeting 2013

Nano-sized EVs play role in cancer growth and survival

Study: Chicken-killing virus is a promising treatment for prostate cancer

University of Leicester to launch new research centre to explore complex traits and disease

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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