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UT Southwestern scientists identify new biomarker that could optimize chemotherapy response

UT Southwestern Medical Center scientists have identified a new biomarker that could help identify patients who are more likely to respond to certain chemotherapies.

18 Feb 2015

Findings may help doctors recommend appropriate treatments, improve patient outcomes

Like a car's front and back bumpers, your cell's chromosomes are capped by "telomeres" that protect this genetic material against deterioration. Still, after enough replications, a chromosome's telomeres break down and once they reach a certain point of degradation, the cell dies. This is one reason that cells are mortal: telomeres only last so long. That is, unless the enzyme telomerase builds new material onto the worn telomeres to reinforce these chromosomal "bumpers". Telomere repair can be a good thing, but in some cases it's not: overactive telomerase can lengthen telomeres until a cell becomes immortal…leading to cancer.

18 Feb 2015

UT Southwestern researchers find that acetate speeds up growth and metastasis of tumors

UT Southwestern Medical Center researchers seeking novel ways to combat cancer found that giving acetate, a major compound produced in the gut by host bacteria, to mice sped up the growth and metastasis of tumors.

18 Feb 2015

Researchers show importance of DNA damage in fine tuning of innate immune system

For the first time scientists from Umeå University show the importance of DNA damage in fine tuning of our innate immune system and hence the ability to mount the optimal inflammatory response to infections and other biological dangers.

18 Feb 2015

Recent clinical study offers hope for potential Parkinson's disease therapies

Researchers have long sought treatments that can slow the progression of Parkinson's disease. Current treatments have for decades been only symptomatic in nature, supplying the neurotransmitter dopamine, which the dying nerve cells can no longer produce.

18 Feb 2015

From the scent of geranium to cough medicine; A self-assembling catalyst helps to construct complex biological scaffolds

With great elegance nature builds up complex structures from simple building blocks. A central class of compounds are terpenes. More than 8000 terpenes and about 30,000 of the related terpenoids are currently known. They are the key substances for many biological and pharmaceutical functions.

18 Feb 2015

Polypropylene PCR plates

To ensure full compatibility with robotic systems, DNase / RNase- and pyrogen-free PCR plates from Porvair Sciences feature high rigidity to minimise distortion before and after thermal cycling.

From Porvair Sciences Limited 18 Feb 2015

Scientists identify role of tau-associated MAPT gene in development of Alzheimer's disease

An international team of scientists, led by researchers at the University of California, San Diego School of Medicine, has identified the microtubule-associated protein tau (MAPT) gene as increasing the risk for developing Alzheimer's disease (AD).

18 Feb 2015

SLU researchers halt fatty liver disease in animal model

Doctors believe that up to 30 percent of the U.S. population may have fat accumulation in the liver, known as non-alcoholic fatty liver disease (NAFLD), that can lead to a range of damaging health consequences.

18 Feb 2015

Research may lead to future medical treatments for children with neurodevelopmental problems

Children born with a DNA abnormality on chromosome 16 already linked to neurodevelopmental problems show measurable delays in processing sound and language, says a study team of radiologists and psychologists.

18 Feb 2015

New compound appears to play role in development of opioid tolerance

While opioids are a widely used treatment for pain, patients who take them on a regular basis can become tolerant, requiring a higher dose for continued pain relief. In a study published in Anesthesiology, the official medical journal of the American Society of Anesthesiologists, researchers identified a compound that appears to play a role in the development of opioid tolerance.

18 Feb 2015

Fetal exposure to drugs can cause neurological problems

Research suggests that fetal exposure to chemicals or drugs can cause neurological problems. Babies whose mothers take the epilepsy drug valporic acid (VPA) during pregnancy, for example, appear to have an elevated risk of developing an autism spectrum disorder.

18 Feb 2015

Vanderbilt scientists shed new light on how the brain executes 'mental time travel'

In Proust's novel Recollection of Things Past, the distinctive smell of a lemon madeleine launches the narrator on a long, involved reminiscence of his past that fills seven chapters.

18 Feb 2015

New class of experimental drug could help patients with bile duct cancer

Patients with bile duct cancer could be helped by a new class of experimental drug, a study has shown.

18 Feb 2015

New discovery could lead to potential treatment for preventing blindness

Scientists have made a major new discovery detailing how areas of the brain responsible for vision could potentially adapt to injury or trauma and ultimately prevent blindness.

18 Feb 2015

Researchers identify molecule that can block progression of Alzheimer's disease

A molecule that can block the progress of Alzheimer's disease at a crucial stage in its development has been identified by researchers in a new study, raising the prospect that more such molecules may now be found.

18 Feb 2015

RUB scientists examine distributed, local activity patterns during spatial navigation

How do we know where we are at any given moment? How do we remember routes that we've walked? Spatial navigation has long been a subject of psychological and brain research. "It is likely that there is more than one spatial navigation mechanism; rather, the brain uses different 'codes' to memorise locations," says Nikolai Axmacher.

18 Feb 2015

Trinity scientists reveal new marvel molecule that can block key process in inflammatory diseases

Scientists at Trinity College Dublin have uncovered a marvel molecule that blocks a key driver of inflammatory diseases. The finding could meet a major unmet clinical need by inspiring new non-invasive treatments for arthritis, multiple sclerosis and Muckle-Wells syndrome, among a myriad of other inflammatory diseases.

18 Feb 2015

UT Arlington chemist receives NIH's Academic Research Enhancement Award for protein research

A University of Texas at Arlington bio-analytical chemist exploring proteins, their structures and functions by using cutting-edge analytical instrumentation called mass spectrometry has received an Academic Research Enhancement Award from the National Institutes of Health.

18 Feb 2015

CAMH scientists discover potential new approach to treat multiple sclerosis

Scientists at the Centre for Addiction and Mental Health have discovered a promising new approach to treat multiple sclerosis (MS). In a new study, they've identified a previously unknown change in the spinal cord related to MS, and a way to alter this change to reduce the nerve cell damage that occurs with the disease.

18 Feb 2015

Medical Science News

UT Southwestern scientists identify new biomarker that could optimize chemotherapy response

Findings may help doctors recommend appropriate treatments, improve patient outcomes

UT Southwestern researchers find that acetate speeds up growth and metastasis of tumors

Researchers show importance of DNA damage in fine tuning of innate immune system

Recent clinical study offers hope for potential Parkinson's disease therapies

From the scent of geranium to cough medicine; A self-assembling catalyst helps to construct complex biological scaffolds

Polypropylene PCR plates

Scientists identify role of tau-associated MAPT gene in development of Alzheimer's disease

SLU researchers halt fatty liver disease in animal model

Research may lead to future medical treatments for children with neurodevelopmental problems

New compound appears to play role in development of opioid tolerance

Fetal exposure to drugs can cause neurological problems

Vanderbilt scientists shed new light on how the brain executes 'mental time travel'

New class of experimental drug could help patients with bile duct cancer

New discovery could lead to potential treatment for preventing blindness

Researchers identify molecule that can block progression of Alzheimer's disease

RUB scientists examine distributed, local activity patterns during spatial navigation

Trinity scientists reveal new marvel molecule that can block key process in inflammatory diseases

UT Arlington chemist receives NIH's Academic Research Enhancement Award for protein research

CAMH scientists discover potential new approach to treat multiple sclerosis

The future of automation: Machine learning–driven hepatocyte and organoid counting

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

Reimagining light scattering for biotherapeutics

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