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Scientists identify small RNA molecule that can suppress cancer-causing genes in GBM

Northwestern Medicine scientists have identified a small RNA molecule called miR-182 that can suppress cancer-causing genes in mice with glioblastoma mulitforme (GBM), a deadly and incurable type of brain tumor.

6 Apr 2015

Mayo Clinic-led researchers combine genetic variants to improve identification of women with breast cancer

Recent large-scale genomic analyses have uncovered dozens of common genetic variants that are associated with breast cancer. Each variant, however, contributes only a tiny amount to a person's overall risk of developing the disease.

6 Apr 2015

New approach could help identify novel drug targets to combat lethal fungal infections

By modifying the CRISPR-Cas genome editing system, Whitehead Institute researchers are now able to manipulate Candida albicans' genome systematically--an approach that could help identify novel targets for therapies against this serious pathogen for which there are a limited number of anti-fungal agents.

6 Apr 2015

Combination of signaling molecules can inhibit growth of breast cancer cells

Researchers at UT Southwestern Medical Center have uncovered how the body's inflammatory response can alter how estrogen promotes the growth of breast cancer cells.

6 Apr 2015

Nanomedicine strategy can help reduce heart attacks, strokes

A research team showed that a nanotherapeutic medicine can halt the growth of artery plaque cells resulting in the fast reduction of the inflammation that may cause a heart attack, according to a study led by researchers from Icahn School of Medicine at Mount Sinai and published April 3 in Science Advances.

6 Apr 2015

CentoMD: World's largest genetic mutation database for rare diseases

CENTOGENE AG announces the launch of the world's largest genetic mutation database for rare diseases, CentoMD. CentoMD is a comprehensive and unique repository of genetic variants, including a huge number of unpublished pathogenic variants gathered from patients worldwide.

3 Apr 2015

New biodegradable membrane reduces wound healing time by 50%

Treatments to regenerate skin from burns become tedious and long lasting; however, Mexican researchers developed a biodegradable membrane that allows to transfer skin cells (keratinocytes) to burn wounds, when placed on the wound. The method reduces healing time by 50 percent.

3 Apr 2015

Dartmouth researchers use new strategies to target drug-resistant pathogens

By engineering antibacterial enzymes, Dartmouth investigators led by Karl Griswold, PhD are using novel strategies to target the prevalent drug-resistant bacterium Staphylococcus aureus.

3 Apr 2015

Adolescent binge-drinking alters genes needed for normal brain maturation

Binge-drinking during adolescence may perturb brain development at a critical time and leave lasting effects on genes and behavior that persist into adulthood.

3 Apr 2015

Clinical trial uses personalized cellular therapy to treat GVHD complication of bone marrow transplant

An innovative clinical trial using the science of "personalized" cellular therapy has begun enrolling children and adults suffering from graft-versus-host-disease (GVHD), a life-threatening complication of bone marrow transplantation in which donor immune lymphocytes attack the organs of the bone marrow transplant recipient.

3 Apr 2015

Peripheral inflammatory cells play role in Parkinson's disease

A small area in the midbrain known as the substantia nigra is the control center for all bodily movement. Increasing loss of dopamine-generating neurons in this part of the brain therefore leads to the main symptoms of Parkinson's disease - slowness of movement, rigidity and shaking.

3 Apr 2015

Mouse model may help understand the physiology behind complex brain disorders

Complex brain disorders, such as autism or schizophrenia, still puzzle scientists because their causes lie hidden in early events of brain development, which are still poorly understood.

3 Apr 2015

A new amyloid-targeting treatment for Alzheimer's disease

With each new amyloid-targeting treatment for Alzheimer's disease that has been developed, there has been a corresponding concern. For example, antibodies targeting amyloid-β peptide (Aβ) produce inflammation in the brain in some patients.

3 Apr 2015

Nanoparticle technique inhibits tumor growth, prolongs survival in animal models

Delving into the world of the extremely small, researchers are exploring how biodegradable nanoparticles can precisely deliver anticancer drugs to attack neuroblastoma, an often-deadly children's cancer.

3 Apr 2015

Elsevier invites submission for its new open-access journal, Heliyon

Elsevier, a world-leading provider of scientific, technical and medical information products and services, has announced the call for submissions for its new open access journal Heliyon.

3 Apr 2015

Research may point to new paradigms in diagnosis, treatment of aggressive cancers

All living things--from dandelions to reindeer--evolve over time. Cancer cells are no exception, and are subject to the two overarching mechanisms described by Charles Darwin: chance mutation and natural selection.

3 Apr 2015

Research shows that hippocampus is dedicated to memory formation, not to spatial skills

In work that reconciles two competing views of brain structures involved in memory and spatial perception, researchers at University of California, San Diego School of Medicine have conducted experiments that suggest the hippocampus - a small region in the brain's limbic system - is dedicated largely to memory formation and not to spatial skills, such as navigation.

3 Apr 2015

Pseudogenes may play role in cancer development, shows study

Pseudogenes, a sub-class of long non-coding RNA (lncRNA) that developed from the genome's 20,000 protein-coding genes but lost the ability to produce proteins, have long been considered nothing more than genomic "junk." Yet the retention of these 20,000 mysterious remnants during evolution has suggested that they may in fact possess biological functions and contribute to the development of disease.

3 Apr 2015

Researchers test effects of light therapy on brain function

Following up on promising results from pilot work, researchers at the VA Boston Healthcare System are testing the effects of light therapy on brain function in veterans with Gulf War Illness.

3 Apr 2015

SGI-DNA introduces BioXp system to give researchers priority access to personal DNA work station

SGI-DNA Inc. today announced the launch of the BioXp 3200 System Early Access Program giving researchers priority access to this one of a kind, personal DNA work station which delivers high quality synthetic DNA fragments.

2 Apr 2015

Medical Science News

Scientists identify small RNA molecule that can suppress cancer-causing genes in GBM

Mayo Clinic-led researchers combine genetic variants to improve identification of women with breast cancer

New approach could help identify novel drug targets to combat lethal fungal infections

Combination of signaling molecules can inhibit growth of breast cancer cells

Nanomedicine strategy can help reduce heart attacks, strokes

CentoMD: World's largest genetic mutation database for rare diseases

New biodegradable membrane reduces wound healing time by 50%

Dartmouth researchers use new strategies to target drug-resistant pathogens

Adolescent binge-drinking alters genes needed for normal brain maturation

Clinical trial uses personalized cellular therapy to treat GVHD complication of bone marrow transplant

Peripheral inflammatory cells play role in Parkinson's disease

Mouse model may help understand the physiology behind complex brain disorders

A new amyloid-targeting treatment for Alzheimer's disease

Nanoparticle technique inhibits tumor growth, prolongs survival in animal models

Elsevier invites submission for its new open-access journal, Heliyon

Research may point to new paradigms in diagnosis, treatment of aggressive cancers

Research shows that hippocampus is dedicated to memory formation, not to spatial skills

Pseudogenes may play role in cancer development, shows study

Researchers test effects of light therapy on brain function

SGI-DNA introduces BioXp system to give researchers priority access to personal DNA work station

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

Exploring electron microscopy for plant and microbial imaging at the John Innes Centre

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