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Protein p66ShcA shows promise as biomarker to identify breast cancers with poor prognoses

A protein named p66ShcA shows promise as a biomarker to identify breast cancers with poor prognoses, according to research published ahead of print in the journal Molecular and Cellular Biology.

26 Aug 2014

Researchers report that predominant CA-MRSA strain migrated from sub-Saharan Africa

The predominant strain of community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) infecting people in Europe, the Middle East and northern Africa derived from a single sub-Saharan ancestor, a team of international researchers reported this week in mBio-, the online open-access journal of the American Society for Microbiology.

26 Aug 2014

Spanish scientists explore genetic basis of familial extreme longevity

In a recent report in Aging Cell, a multidisciplinary team of Spanish scientists, led by Tim Cash and Manuel Serrano at the Spanish National Cancer Research Centre, identify rare variants in the APOB gene in several families where exceptional longevity (>100 years of age) appears to cluster.

26 Aug 2014

Repurposing anti-depressant medication to target new pathway may help combat medulloblastoma

An international research team reports in Nature Medicine a novel molecular pathway that causes an aggressive form of medulloblastoma, and suggests repurposing an anti-depressant medication to target the new pathway may help combat one of the most common brain cancers in children.

26 Aug 2014

Researchers show how neurons respond to sequences of familiar objects

The world grows increasingly more chaotic year after year, and our brains are constantly bombarded with images.

26 Aug 2014

Researchers show how interplay between nutrition, metabolism, immunity involved in ageing process

Researchers from UCL (University College London) have demonstrated how an interplay between nutrition, metabolism and immunity is involved in the process of ageing.

26 Aug 2014

New ingredient in gluten-free products can cause allergic reaction

A popular new ingredient in gluten-free products could be causing an allergic reaction, according to a Kansas State University food safety specialist.

26 Aug 2014

Scientists identify number of compounds to treat cancer could add to anti-malarial arsenal

Scientists searching for new drugs to fight malaria have identified a number of compounds -- some of which are currently in clinical trials to treat cancer -- that could add to the anti-malarial arsenal.

26 Aug 2014

Drug to kill limited type of cancer cells with DNA repair defects could treat leukaemia

A team of scientists led by Research Associate Professor Motomi Osato and Professor Yoshiaki Ito from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS) found that a drug originally designed for killing a limited type of cancer cells with DNA repair defects could potentially be used to treat leukaemia and other cancers.

26 Aug 2014

Female rats whose great grandparents exposed to toxins become more vulnerable to stress

Scientists have known that toxic effects of substances known as endocrine disrupting chemicals (EDCs), found in both natural and human-made materials, can pass from one generation to the next, but new research shows that females with ancestral exposure to EDC may show especially adverse reactions to stress.

26 Aug 2014

UT Southwestern researchers discover crucial link between high insulin levels and obesity pathways

UT Southwestern Medical Center researchers have identified a crucial link between high levels of insulin and pathways that lead to obesity, a finding that may have important implications when treating diabetes.

26 Aug 2014

TIM-family proteins also have ability to block release of HIV and other viruses

A family of proteins that promotes virus entry into cells also has the ability to block the release of HIV and other viruses, University of Missouri researchers have found.

26 Aug 2014

Researchers find why certain glioblastomas become drug resistance

Researchers at the University of California, San Diego School of Medicine have found one of the keys to why certain glioblastomas - the primary form of a deadly brain cancer - are resistant to drug therapy.

26 Aug 2014

Spring Bioscience launches PD-L1 (SP142) rabbit monoclonal immunohistochemistry antibody1

Spring Bioscience (Spring), a member of the Roche Group, today announced the launch of its PD-L1 (SP142) rabbit monoclonal immunohistochemistry (IHC) antibody.

25 Aug 2014

Finding suggests that retina acts as type of window to the brain

Researchers at the Gladstone Institutes and University of California, San Francisco have shown that a loss of cells in the retina is one of the earliest signs of frontotemporal dementia (FTD) in people with a genetic risk for the disorder-even before any changes appear in their behavior.

25 Aug 2014

Statistical genetic analysis can detect aggressiveness of lymphoma

Each year, more than one thousand Norwegians develop lymphoma. A statistical genetic analysis can detect when the disease will be aggressive. Thereby, treatment can be initiated in time.

25 Aug 2014

Researchers endow mice with greater touch sensitivity by striking brain rhythm

By striking up the right rhythm in the right brain region at the right time, Brown University neuroscientists report in Nature Neuroscience that they managed to endow mice with greater touch sensitivity than other mice, making hard-to-perceive vibrations suddenly more vivid to them.

25 Aug 2014

Study finds a host of new clues on gene-environment interactions in Crohn's disease

A new study finds a wide range of epigenetic changes-alterations in DNA across the genome that may be related to key environmental exposures-in children with Crohn's disease (CD), reports Inflammatory Bowel Diseases, official journal of the Crohn's & Colitis Foundation of America.

23 Aug 2014

New mouse model to open door to research on epilepsy, Alzheimer's

University of Utah scientists have developed a genetically engineered line of mice that is expected to open the door to new research on epilepsy, Alzheimer's and other diseases.

22 Aug 2014

Understanding neuron development: an interview with Dr. Brock Grill, The Scripps Research Institute

There’s a big difference between understanding coordination and actually building connectivity. In terms of building connectivity, several molecules have been identified that control this process and a lot has been learned from both genetic and biochemical research in a variety of different systems, particularly studies in the nematode C. elegans, the fruit fly Drosophila and mice.

22 Aug 2014

Medical Science News

Protein p66ShcA shows promise as biomarker to identify breast cancers with poor prognoses

Researchers report that predominant CA-MRSA strain migrated from sub-Saharan Africa

Spanish scientists explore genetic basis of familial extreme longevity

Repurposing anti-depressant medication to target new pathway may help combat medulloblastoma

Researchers show how neurons respond to sequences of familiar objects

Researchers show how interplay between nutrition, metabolism, immunity involved in ageing process

New ingredient in gluten-free products can cause allergic reaction

Scientists identify number of compounds to treat cancer could add to anti-malarial arsenal

Drug to kill limited type of cancer cells with DNA repair defects could treat leukaemia

Female rats whose great grandparents exposed to toxins become more vulnerable to stress

UT Southwestern researchers discover crucial link between high insulin levels and obesity pathways

TIM-family proteins also have ability to block release of HIV and other viruses

Researchers find why certain glioblastomas become drug resistance

Spring Bioscience launches PD-L1 (SP142) rabbit monoclonal immunohistochemistry antibody1

Finding suggests that retina acts as type of window to the brain

Statistical genetic analysis can detect aggressiveness of lymphoma

Researchers endow mice with greater touch sensitivity by striking brain rhythm

Study finds a host of new clues on gene-environment interactions in Crohn's disease

New mouse model to open door to research on epilepsy, Alzheimer's

Understanding neuron development: an interview with Dr. Brock Grill, The Scripps Research Institute

Synthetic Biology and the Pursuit of Living Diagnostics

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

Evolving spectrophotometry for modern biopharma workflows

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