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Research offers promise for personalized RNA combination therapies to treat lung cancer

Small RNA molecules, including microRNAs (miRNAs) and small interfering RNAs (siRNAs), offer tremendous potential for new therapeutic agents to inhibit cancer cell growth. However, delivering these small RNAs to solid tumors remains a significant challenge, as the RNAs must target the correct cells and avoid being broken down by enzymes in the body.

15 Aug 2014

Researchers develop new lung-on-chip model for laboratory studies of respiratory challenges

Researchers at RTI International, in collaboration with the University of North Carolina at Chapel Hill, have developed a new lung-on-chip microdevice for laboratory studies of respiratory challenges and therapeutics. The microdevice includes multiple vertically stacked cellular layers that mimic the structure of the airway tissue.

15 Aug 2014

New therapeutic strategy to combat common genetic risk factor for ALS, FTD

A team of researchers at Mayo Clinic and The Scripps Research Institute in Florida have developed a new therapeutic strategy to combat the most common genetic risk factor for the neurodegenerative disorders amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease) and frontotemporal dementia (FTD).

15 Aug 2014

NTU research could lead to better treatment options for children suffering from leukaemia

A research team led by Nanyang Technological University scientists have made a key finding which is expected to open up improved treatment possibilities for children suffering from leukaemia.

15 Aug 2014

HDAC inhibitors may also be effective against kidney stones

Anyone who has suffered from kidney stones is keenly aware of the lack of drugs to treat the condition, which often causes excruciating pain.

15 Aug 2014

Modified C. novyi-NT bacterium produces precisely targeted anti-tumor response

A modified version of the Clostridium novyi (C. novyi-NT) bacterium can produce a strong and precisely targeted anti-tumor response in rats, dogs and now humans, according to a new report from Johns Hopkins Kimmel Cancer Center researchers.

14 Aug 2014

Yizhijiannao granule may exert therapeutic effect by inhibiting neural cell apoptosis

Previous studies have shown that Yizhijiannao granule can enhance cognitive performance in Alzheimer's disease patients and Alzheimer's disease-model mice.

14 Aug 2014

AEG-1 protein blocks effects of retinoic acid in leukemia and liver cancer

Retinoic acid is a form of vitamin A that is used to treat and help prevent the recurrence of a variety of cancers, but for some patients the drug is not effective.

14 Aug 2014

Researchers find method to repair gene mutation causing autoimmune deficiency disease

Researchers at Karolinska Institutet in Sweden have found a method to repair the gene mutation causing agammaglobulinemia, an autoimmune deficiency disease that almost exclusively affects boys and in which the body lacks the ability to produce immunoglobulins (gamma globulin).

14 Aug 2014

Researchers reveal importance of highly specialised immune cells in killing melanoma cells

Melbourne researchers have revealed the critical importance of highly specialised immune cells, called natural killer cells, in killing melanoma cells that have spread to the lungs.

14 Aug 2014

Researchers show effects of increased and decreased sodium intake on blood pressure

Two reports from a global collaborative study involving hundreds of investigators from 18 countries published today in the New England Journal of Medicine are shaking up conventional wisdom around salt consumption.

14 Aug 2014

Researchers find crucial signaling pathway that helps HSCs to generate

Hematopoietic stem cells (HSCs) give rise to all other blood cell types, but their development and how their fate is determined has long remained a mystery.

14 Aug 2014

Researchers develop artificial connection from brain to legs by bypassing with computer interface

Gait disturbance in individuals with spinal cord injury is attributed to the interruption of neural pathways from brain to the spinal locomotor center, whereas neural circuits locate below and above the lesion maintain most of their functions.

14 Aug 2014

Ebola virus defeats attempts by interferon to block viral reproduction in infected cells

One of the human body's first responses to a viral infection is to make and release signaling proteins called interferons, which amplify the immune system response to viruses.

14 Aug 2014

2 active ingredients in household cleaning products cause declines in mouse reproduction

Virginia Tech researchers who were using a disinfectant when handling mice have discovered that two active ingredients in it cause declines in mouse reproduction.

14 Aug 2014

Injections of anaerobic bacteria can shrink tumors in rats, dogs and human

Deep within most tumors lie areas that remain untouched by chemotherapy and radiation. These troublesome spots lack the blood and oxygen needed for traditional therapies to work, but provide the perfect target for a new cancer treatment using bacteria that thrive in oxygen-poor conditions.

14 Aug 2014

More than ½ of emergency department patients age 65 and older are malnourished

More than half of emergency department patients age 65 and older who were seen at UNC Hospitals during an 8-week period were either malnourished or at risk for malnutrition.

14 Aug 2014

Researchers find that nanopores in material MoS2 could sequence DNA more accurately

Gene-based personalized medicine has many possibilities for diagnosis and targeted therapy, but one big bottleneck: the expensive and time-consuming DNA-sequencing process.

14 Aug 2014

Combination of NASBA and real-time qPCR detects aspergillosis with 100% accuracy

The fungal infection invasive aspergillosis (IA) can be life threatening, especially in patients whose immune systems are weakened by chemotherapy or immunosuppressive drugs. Despite the critical need for early detection, IA remains difficult to diagnose.

14 Aug 2014

Scientists identify gene that regulates sleep and wake rhythms

Scientists at the Salk Institute for Biological Studies have identified a gene that regulates sleep and wake rhythms.

14 Aug 2014

Medical Science News

Research offers promise for personalized RNA combination therapies to treat lung cancer

Researchers develop new lung-on-chip model for laboratory studies of respiratory challenges

New therapeutic strategy to combat common genetic risk factor for ALS, FTD

NTU research could lead to better treatment options for children suffering from leukaemia

HDAC inhibitors may also be effective against kidney stones

Modified C. novyi-NT bacterium produces precisely targeted anti-tumor response

Yizhijiannao granule may exert therapeutic effect by inhibiting neural cell apoptosis

AEG-1 protein blocks effects of retinoic acid in leukemia and liver cancer

Researchers find method to repair gene mutation causing autoimmune deficiency disease

Researchers reveal importance of highly specialised immune cells in killing melanoma cells

Researchers show effects of increased and decreased sodium intake on blood pressure

Researchers find crucial signaling pathway that helps HSCs to generate

Researchers develop artificial connection from brain to legs by bypassing with computer interface

Ebola virus defeats attempts by interferon to block viral reproduction in infected cells

2 active ingredients in household cleaning products cause declines in mouse reproduction

Injections of anaerobic bacteria can shrink tumors in rats, dogs and human

More than ½ of emergency department patients age 65 and older are malnourished

Researchers find that nanopores in material MoS2 could sequence DNA more accurately

Combination of NASBA and real-time qPCR detects aspergillosis with 100% accuracy

Scientists identify gene that regulates sleep and wake rhythms

Synthetic Biology and the Pursuit of Living Diagnostics

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

Evolving spectrophotometry for modern biopharma workflows

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