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C. elegans model system accelerates discovery of amyloid inhibitors

An international team led by researchers at the University of Toronto has developed an efficient and robust system, using the C. elegans nematode, to screen for compounds that can stop the growth of amyloid proteins.

28 Oct 2024

Genomic technology used to improve understanding of Marjolin's ulcer

Researchers utilized specialized genomic technology at the University of Calgary to enhance our understanding of Marjolin's ulcer (MU), a rare, highly aggressive skin cancer that affects chronic wounds that can often arise from established scars like those caused by severe burns.

28 Oct 2024

Researchers discover key biochemical mechanism in Huntington's disease development

Researchers from the University of Oxford have identified a key biochemical mechanism relevant to the development of Huntington's Disease.

28 Oct 2024

Elucidating the mechanisms behind kidney development

To Alex Hughes, Assistant Professor in Bioengineering within Penn Engineering and in Cell and Developmental Biology within Penn Medicine, the kidney is a work of art. "I find the development of the kidney to be a really beautiful process," says Hughes.

28 Oct 2024

Study highlights the potential of psilocybin in treating obsessive-compulsive disorder

A new study highlights the potential of psilocybin, a psychedelic compound, in treating obsessive-compulsive disorder (OCD) and Tourette's Syndrome.

28 Oct 2024

A promising visual sign for concussion diagnosis in athletes

Researchers investigate how spontaneous headshake after a kinematic event (SHAAKE) may be a novel sign to diagnose concussion.

28 Oct 2024

Inside the Alzheimer's Association: Dr. Heather Snyder on Driving Research and Collaboration

Heather Snyder discusses the Alzheimer's Association's research initiatives, breakthroughs in diagnostics, and the importance of collaboration in dementia care.

28 Oct 2024

Study finds pistachios might help guard against vision loss

A study finds that pistachio consumption significantly increases macular pigment optical density, potentially protecting against vision loss in healthy adults.

28 Oct 2024

Ozempic effective for patients with chronic kidney damage

In a 24-week trial, semaglutide led to a 52% reduction in albuminuria and improved kidney health in individuals with chronic kidney disease and obesity.

28 Oct 2024

New research explores how antimicrobial exposure affects Parkinson’s disease risk

Antibiotic exposure shows potential protective effects against Parkinson's, while antifungal use is linked to increased risk, indicating microbiome involvement.

28 Oct 2024

Can a mushroom protein bar improve memory? Study suggests cognitive benefits of Termitomyces fuliginosus

The FCM protein snack bar, rich in amino acids and antioxidants, improves brain function and memory accuracy in just six weeks, according to recent research.

28 Oct 2024

Expanded access to weight-loss drugs could save thousands of lives

Researchers explore the potential benefits of expanding access to novel weight loss drugs to enhance survival rates in overweight and obese individuals.

28 Oct 2024

Ground beef vs. soy-based meat: Which packs more muscle-building power?

Researchers compare the effectiveness of plant-based meat alternatives and ground beef in stimulating muscle protein synthesis.

28 Oct 2024

Scientists uncover "superspreader" fibrils driving Alzheimer's Disease

The treatment of dementia disorders such as Alzheimer's is still one of the greatest challenges facing modern medicine. In the course of neurodegenerative diseases, certain proteins such as the amyloid β protein accumulate in the brain. They are suspected of being linked to the development of the disease, which is why they are considered a promising target for therapeutic approaches.

28 Oct 2024

New model sheds light on the genetic roots of polygenic diseases

Many statistical models and algorithms used by scientists can be imagined as a "black box." These models are powerful tools that give accurate predictions, but their internal workings are not easily interpretable or understood.

28 Oct 2024

Clinical utility of carbonic anhydrase IX in diagnosing pleural mesothelioma

Mesothelioma is an aggressive tumor with a poor prognosis. Histological diagnosis of mesothelioma using limited tissue samples can be challenging.

27 Oct 2024

Impact of TLR10 rs10004195 genotype on susceptibility to H. pylori infection

Helicobacter pylori (H. pylori) infection can cause multiple secondary digestive disorders. Some studies have found that polymorphisms in Toll-like receptor (TLR) genes, including TLR10 rs10004195, may be associated with increased susceptibility to H. pylori infection. Despite conflicting reports, we conducted a meta-analysis to clarify the relationship between these factors.

26 Oct 2024