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Oxford Gene Technology releases next generation sequencing survey results

Oxford Gene Technology, provider of innovative genetics research and biomarker solutions to advance molecular medicine, has released the results from a recent survey of researchers using next generation sequencing.

From Oxford Gene Technology 21 Aug 2013

CO diffusion across gypsum wallboard may explain at least some instances of CO poisoning

"Carbon monoxide (CO) poisoning is a significant U.S. health problem, responsible for approximately 500 accidental deaths annually, and a risk of 18 percent to 35 percent for cognitive brain injury 1 year after poisoning.

21 Aug 2013

Researchers identify gene that contributes to development of acute myeloid leukemia

Researchers at the University of Chicago Medicine Comprehensive Cancer Center (UCCCC) have identified a gene that contributes to the development of acute myeloid leukemia (AML). This pivotal finding follows 40 years of University of Chicago research that has slowly unraveled the genetic basis of leukemia.

21 Aug 2013

Researchers identify genome-wide locus for serious gastrointestinal condition in infants

Researchers have identified a new genome-wide significant locus (the place a gene occupies on a chromosome) for infantile hypertrophic pyloric stenosis (IHPS), a serious gastrointestinal condition associated with gastrointestinal obstruction, according to a study in the August 21 issue of JAMA. Characteristics of this locus also suggest the possibility of an inverse relationship between levels of circulating cholesterol in neonates and IHPS risk.

21 Aug 2013

Asthma sufferers exposed to heavy traffic pollution or wood smoke experience worse symptoms

Asthma sufferers frequently exposed to heavy traffic pollution or smoke from wood fire heaters, experienced a significant worsening of symptoms, a new University of Melbourne led study has found.

21 Aug 2013

Scientists report possible basis for why food-restricted animals show susceptibility to drugs of abuse

Scientists today reported a possible basis for why food-restricted animals show increased susceptibility to drugs of abuse. This association has puzzled researchers since it was first observed more than three decades ago.

21 Aug 2013

Noninvasive measure of oxygen levels in leg muscles improves outcomes in peripheral arterial disease patients

For millions of Americans, simply walking to the mailbox can cause unbearable leg pain as muscles scream for more blood and oxygen.

21 Aug 2013

New insights on cochlea may help develop better hearing devices

A healthy ear is much better at detecting and transmitting sound than even the most advanced hearing aid. But now researchers reporting in the August 20 issue of the Biophysical Journal, a Cell Press publication, have uncovered new insights into how the ear -- in particular, the cochlea -- processes and amplifies sound.

21 Aug 2013

Two proteins identified as prime suspects in proliferation of breast cancer

Two proteins have been identified as prime suspects in the proliferation of breast cancer in a study by an international consortium of researchers from Rice University, the University of North Texas, Denton (UNT); the University of California, San Diego (UCSD); and the Hebrew University of Jerusalem.

21 Aug 2013

New book on evolution and future of human reproduction

Human beings would probably be known as pilosals rather than mammals if Carl Linnaeus had not been a proponent of breast-feeding. For social and political reasons, the famed taxonomist labeled the class of animals to which humans belong with a reference to their practice of suckling their young rather than to their evolutionarily older characteristic of having hair.

21 Aug 2013

Genetics may play role in how people's taste receptors send signals

Genetics may play a role in how people's taste receptors send signals, leading to a wide spectrum of taste preferences, according to Penn State food scientists. These varied, genetically influenced responses may mean that food and drink companies will need a range of artificial sweeteners to accommodate different consumer tastes.

21 Aug 2013

Glucagon loses its ability to help obese people, but continues to suppress hunger pangs

Glucagon, a hormone involved in regulating appetite, loses its ability to help obese people feel full after a meal, but it continues to suppress hunger pangs in people with type 1 diabetes, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).

21 Aug 2013

Researchers find genetic correlation between eating disorders and alcohol dependence

Part of the risk for alcohol dependence is genetic, and the same is true for eating disorders. Now, researchers at Washington University School of Medicine in St. Louis have found it's likely some of the same genes are involved in both.

21 Aug 2013

Study shows how brain integrates inputs from different senses in complex circuits of nerve cells

A new publication in the top-ranked journal Neuron sheds new light onto the unknown processes on how the brain integrates the inputs from the different senses in the complex circuits formed by molecularly distinct types of nerve cells. The work was led by new Ume- University associate professor Paolo Medini.

21 Aug 2013

UC Davis graduate discovers how eIF4E protein acts upon cancer-promoting mRNA molecules

Researchers have long known that high levels of a specific protein in human cells are linked to tumor growth - but no one has fully understood how.

21 Aug 2013

Research suggests gene therapy approach may be feasible option to treat Rett Syndrome

The concept behind gene therapy is simple: deliver a healthy gene to compensate for one that is mutated. New research published today in the Journal of Neuroscience suggests this approach may eventually be a feasible option to treat Rett Syndrome, the most disabling of the autism spectrum disorders.

21 Aug 2013

Studies reveal potential of HB-EGF in protecting intestines from diverse types of injury

It's not often that one treatment offers therapeutic potential for multiple conditions. However, after more than two decades of research, Gail Besner, MD, principal investigator for the Center for Perinatal Research and pediatric surgeon for the Department of Pediatric Surgery at Nationwide Children's Hospital, and her team have found that this may just be the case with HB-EGF, or heparin-binding EGF-like growth factor.

21 Aug 2013

Sodium act as "on/off" switch for major neurotransmitter receptor in brain

Researchers at McGill University have found that sodium - the main chemical component in table salt - is a unique "on/off" switch for a major neurotransmitter receptor in the brain. This receptor, known as the kainate receptor, is fundamental for normal brain function and is implicated in numerous diseases, such as epilepsy and neuropathic pain.

21 Aug 2013

Combination of anti-nausea drug and turmeric spice target cancer cells

In a laboratory, preclinical study recently published by the journal Organic & Biomolecular Chemistry, Virginia Commonwealth University Massey Cancer Center researchers combined structural features from anti-nausea drug thalidomide with common kitchen spice turmeric to create hybrid molecules that effectively kill multiple myeloma cells.

20 Aug 2013

3-D structure of proteins show flame retardants can mimic estrogen hormones

By determining the three-dimensional structure of proteins at the atomic level, researchers at the National Institutes of Health have discovered how some commonly used flame retardants, called brominated flame retardants (BFRs), can mimic estrogen hormones and possibly disrupt the body's endocrine system. BFRs are chemicals added or applied to materials to slow or prevent the start or growth of fire.

20 Aug 2013

Medical Science News

Oxford Gene Technology releases next generation sequencing survey results

CO diffusion across gypsum wallboard may explain at least some instances of CO poisoning

Researchers identify gene that contributes to development of acute myeloid leukemia

Researchers identify genome-wide locus for serious gastrointestinal condition in infants

Asthma sufferers exposed to heavy traffic pollution or wood smoke experience worse symptoms

Scientists report possible basis for why food-restricted animals show susceptibility to drugs of abuse

Noninvasive measure of oxygen levels in leg muscles improves outcomes in peripheral arterial disease patients

New insights on cochlea may help develop better hearing devices

Two proteins identified as prime suspects in proliferation of breast cancer

New book on evolution and future of human reproduction

Genetics may play role in how people's taste receptors send signals

Glucagon loses its ability to help obese people, but continues to suppress hunger pangs

Researchers find genetic correlation between eating disorders and alcohol dependence

Study shows how brain integrates inputs from different senses in complex circuits of nerve cells

UC Davis graduate discovers how eIF4E protein acts upon cancer-promoting mRNA molecules

Research suggests gene therapy approach may be feasible option to treat Rett Syndrome

Studies reveal potential of HB-EGF in protecting intestines from diverse types of injury

Sodium act as "on/off" switch for major neurotransmitter receptor in brain

Combination of anti-nausea drug and turmeric spice target cancer cells

3-D structure of proteins show flame retardants can mimic estrogen hormones

How does norepinephrine influence anxiety-related behaviours?

Transforming Lab Workflows with Cell Culture Automation

Building Bridges to Scalable Allogeneic Cell Therapy

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