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EPHB2 overexpressed in malignant pleural mesothelioma cell lines, find researchers

Malignant mesothelioma is a rare asbestos-associated malignancy with limited therapeutic options. Despite advances in the treatment, the median survival remains 12 months from the time of diagnosis. Increased understanding of the molecular basis for the diverse signaling pathways involved in cancer progression should promote the discovery of novel biomarkers for early diagnosis and potentially lead to more effective therapeutic tools for the disease.

26 Jul 2013

Researchers explain how gut bacteria can inactivate cardiac drugs

For decades, doctors have understood that microbes in the human gut can influence how certain drugs work in the body - by either activating or inactivating specific compounds, but questions have long remained about exactly how the process works.

26 Jul 2013

Researchers uncover way to stop cancer cells using HIF-1 gene through synthetic biology approach

Scientists have discovered a new molecule that prevents cancer cells from responding and surviving when starved of oxygen and which could be developed into new treatments for the disease, according to new research published in the Journal of the American Chemical Society today (Friday).

26 Jul 2013

Silk implants placed in brain of animals may help stop progression of epilepsy

Silk has walked straight off the runway and into the lab. According to a new study published in the Journal of Clinical Investigation, silk implants placed in the brain of laboratory animals and designed to release a specific chemical, adenosine, may help stop the progression of epilepsy.

26 Jul 2013

NeuRA's new $54 million brain research facility opens in Sydney

Brain research in Australia has received a significant boost with the opening of a new $54 million research facility in Sydney.

25 Jul 2013

Gene expression profile test accurately predicts likelihood of metastasis in thymoma patients

Patients diagnosed with thymoma, a rare cancer of the thymus gland, may be able to avoid certain cancer treatments associated with severe adverse events if the results of a new test reveal they are at low risk of metastasis, according to a study published today in the journal PLOS ONE.

25 Jul 2013

Researchers to study knowledge and satisfaction of women who choose DNA prenatal screening test

A recently available DNA-based prenatal blood test used to screen pregnancies for Down syndrome and similar chromosome abnormalities in high-risk women is moving a step closer to use in the general pregnancy population.

From Natera 25 Jul 2013

Study finds that higher-frequency electric current stimulation of the spinal cord reduces pain faster

An animal study in the August issue of Anesthesiology suggests that higher-frequency electric current stimulation of the spinal cord reduced pain quicker and better reached nerves not affected by traditionally used frequencies. A higher frequency and intensity controlled pain faster and more effectively, the study found.

25 Jul 2013

Study may lead to personalized treatments for mitochondrial energy disorders

Researchers have identified a master network of signaling molecules that acts like a "fuse box" to regulate the cellular effects of defective energy flow in mitochondrial respiratory chain diseases—a diverse set of difficult-to-treat genetic-based energy disorders.

25 Jul 2013

Discovery points to new therapeutic strategy for Parkinson's disease

Biologists at The Scripps Research Institute have made a significant discovery that could lead to a new therapeutic strategy for Parkinson's disease.

25 Jul 2013

PerkinElmer enhances Operetta imaging system to perform live cell assays with higher throughput

PerkinElmer, Inc., a global leader focused on the health and safety of people and the environment, has announced enhancements for its Operetta® High Content Imaging System, designed to significantly improve the ability of scientists to perform live cell assays with higher throughput, to help foster a better understanding of normal and aberrant cellular behavior.

25 Jul 2013

Mechanical tension increases nerve density, nerve growth factor expression in scar tissue

Scars are prone to appear at high tension parts, such as the sternum, shoulder and back, which are serious clinical problems. Surgeons reduce scar formation through Z, W, V-Y flap variation and reducing blade tension, but its specific mechanism are still not very clear.

25 Jul 2013

Discovery of pressure-driven infection mechanism opens door to new treatments for viral infections

The virus that causes those painful lip blisters known as cold sores has an internal pressure eight times higher than a car tire, and uses it to literally blast its infectious DNA into human cells, scientists are reporting in a new study.

25 Jul 2013

Perfluoroalkyl substances are crossing blood brain barrier of polar bears

PerFluoroAlkyl Substances (PFASs) and precursor compounds have been used in a wide variety of commercial and industrial products over the past six decades. Applications include water and oil repellent coatings, e.g. for textiles, paper products, carpets and food packaging, pharmaceuticals and surfactants in cleaning products and fire-fighting foams.

25 Jul 2013

Manchester scientists treat fatal genetic brain disease using stem cell gene therapy

Scientists from The University of Manchester have used stem cell gene therapy to treat a fatal genetic brain disease in mice for the first time.

From The University of Manchester 25 Jul 2013

STED-RICS microscopy method records rapid movements of molecules in live samples

The newly developed STED-RICS microscopy method records rapid movements of molecules in live samples. By combining raster image correlation spectroscopy (RICS) with STED fluorescence microscopy, researchers of Karlsruhe Institute of Technology (KIT) opened up new applications in medical research, e.g. analyzing the dynamics of cell membranes at high protein concentrations.

25 Jul 2013

Stem cell-based epilepsy approach may help in search for better medicines to treat seizure disorders

A new stem cell-based approach to studying epilepsy has yielded a surprising discovery about what causes one form of the disease, and may help in the search for better medicines to treat all kinds of seizure disorders.

25 Jul 2013

Infants develop fear of heights as a result of their experiences, says study

Infants develop a fear of heights as a result of their experiences moving around their environments, according to new research published in Psychological Science, a journal of the Association for Psychological Science.

25 Jul 2013

NIAID researchers discover monoclonal antibody can neutralize human norovirus

Researchers from the National Institute of Allergy and Infectious Diseases (NIAID) provide the first proof of concept data showing that a monoclonal antibody can neutralize human norovirus. This research, which could one day lead to effective therapies against the virus, was published online ahead of print in the Journal of Virology.

25 Jul 2013

Researchers find that Notch signaling elevated in tumors relative to normal bone

Many cancers show inappropriate activation of a cell signaling pathway called NOTCH. In the developing body, NOTCH tells brain cells to grow and proliferate. It should be quiet in the adult body, but cancers restart NOTCH to drive their own growth, far and beyond the rate of healthy tissues.

25 Jul 2013

Medical Science News

EPHB2 overexpressed in malignant pleural mesothelioma cell lines, find researchers

Researchers explain how gut bacteria can inactivate cardiac drugs

Researchers uncover way to stop cancer cells using HIF-1 gene through synthetic biology approach

Silk implants placed in brain of animals may help stop progression of epilepsy

NeuRA's new $54 million brain research facility opens in Sydney

Gene expression profile test accurately predicts likelihood of metastasis in thymoma patients

Researchers to study knowledge and satisfaction of women who choose DNA prenatal screening test

Study finds that higher-frequency electric current stimulation of the spinal cord reduces pain faster

Study may lead to personalized treatments for mitochondrial energy disorders

Discovery points to new therapeutic strategy for Parkinson's disease

PerkinElmer enhances Operetta imaging system to perform live cell assays with higher throughput

Mechanical tension increases nerve density, nerve growth factor expression in scar tissue

Discovery of pressure-driven infection mechanism opens door to new treatments for viral infections

Perfluoroalkyl substances are crossing blood brain barrier of polar bears

Manchester scientists treat fatal genetic brain disease using stem cell gene therapy

STED-RICS microscopy method records rapid movements of molecules in live samples

Stem cell-based epilepsy approach may help in search for better medicines to treat seizure disorders

Infants develop fear of heights as a result of their experiences, says study

NIAID researchers discover monoclonal antibody can neutralize human norovirus

Researchers find that Notch signaling elevated in tumors relative to normal bone

How does norepinephrine influence anxiety-related behaviours?

Transforming Lab Workflows with Cell Culture Automation

Building Bridges to Scalable Allogeneic Cell Therapy

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