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Power of taxane-based chemotherapy drugs may be potentially underestimated

The power of taxane-based chemotherapy drugs are misunderstood and potentially underestimated, according to researchers at Weill Cornell Medical College in the September 15 issue of the journal Cancer Research.

18 Sep 2012

ChanTest announces Phase II SBIR grant to optimize cardiomyocyte-based assays

ChanTest, the leading CRO expert in ion channels and nonclinical cardiac safety testing, announces funding of a Phase II SBIR grant. ChanTest will use the grant from the National Heart Lung & Blood Institute to optimize drug safety and discovery assays using stem cell-derived human cardiomyocytes

18 Sep 2012

Study finds major reason why melanoma is largely resistant to chemotherapy

Researchers with UC Irvine's Chao Family Comprehensive Cancer Center have identified a major reason why melanoma is largely resistant to chemotherapy.

18 Sep 2012

ProImmune launches ProStorm in vitro cytokine release assay

ProImmune Ltd., a leader in services for understanding immune responses, announced today the commercial launch of ProStorm, an in vitro cytokine release assay, which can help assess the likelihood of first infusion reactions to novel therapeutics.

18 Sep 2012

BACE2 enzyme could represent powerful new tool against Alzheimer's

An enzyme that could represent a powerful new tool for combating Alzheimer's disease has been discovered by researchers at Mayo Clinic in Florida. The enzyme - known as BACE2 - destroys beta-amyloid, a toxic protein fragment that litters the brains of patients who have the disease.

18 Sep 2012

Biologists elucidate how muscle stem cells colonize special niches

Muscles have a pool of stem cells which provides a source for muscle growth and for regeneration of injured muscles. The stem cells must reside in special niches of the muscle for efficient growth and repair.

18 Sep 2012

Study finds identical strains of antibiotic-resistant C. coli in ABF and conventionally raised pigs

Researchers from North Carolina State University have found identical strains of antibiotic-resistant Campylobacter coli (C. coli) in both antibiotic-free (ABF) and conventionally raised pigs.

18 Sep 2012

Two abnormalities associated with cystic fibrosis-related diabetes

A new University of Iowa study suggests there are two root causes of a type of diabetes associated with cystic fibrosis (CF). The findings, which already have sparked a clinical trial, may guide development of new treatments or even help prevent diabetes in patients with CF.

18 Sep 2012

Researchers to probe causes, treatments of toxic reactions in blood plasma

In the largest undertaking of its kind, scientists at four leading U.S. research institutions are embarking upon a five-year National Institutes of Health (NIH)-funded study to make blood transfusions safer and more effective by uncovering the exact causes of hemoglobin toxicity.

18 Sep 2012

New light-based technique demonstrates that toxic proteins build up gradually in blood cells

A new light-based technique for measuring levels of the toxic protein that causes Huntington's disease (HD) has been used to demonstrate that the protein builds up gradually in blood cells. Published today (17th) in the Journal of Clinical Investigation, the findings shed light on how the protein causes damage in the brain, and could be useful for monitoring the progression of HD, or testing new drugs aimed at suppressing production of the harmful protein.

18 Sep 2012

No association between XMRV/pMLV and chronic fatigue syndrome

The causes of chronic fatigue syndrome (CFS) have long eluded scientists. In 2009, a paper in the journal Science linked the syndrome-sometimes called myalgic encephalomyelitis (ME)-to infection with a mouse retrovirus called XMRV (xenotropic murine leukemia virus (MLV)-related virus).

18 Sep 2012

EMD Millipore announces global licensing agreement for AJ's iPS cell patent portfolio

EMD Millipore, the Life Science division of Merck KGaA of Darmstadt, Germany, and iPS Academia Japan, Inc. today announced a global licensing agreement for AJ's induced pluripotent stem (iPS) cell patent portfolio.

18 Sep 2012

Researchers obtain first detailed and complete picture of PRC2 protein

The first detailed and complete picture of a protein complex that is tied to human birth defects as well as the progression of many forms of cancer has been obtained by an international team of researchers led by scientists with the U.S. Department of Energy (DOE)'s Lawrence Berkeley National Laboratory (Berkeley Lab).

18 Sep 2012

FDA clears Meridian Bioscience’s new illumigene Group A Strep test

Meridian Bioscience, Inc., Cincinnati, Ohio today announced that it has received FDA clearance for a new molecular diagnostic test for Group A Streptococcus on the illumigene platform.

18 Sep 2012

Vitamin E may prevent cancer in patients with Cowden Syndrome

Cleveland Clinic researchers have discovered that vitamin E may prevent cancer in patients with an under-recognized genetic disorder.

18 Sep 2012

UCSF-led research team targets physiological factors that lead to asthma attack

A new study that identifies ways to reduce the factors that lead to an asthma attack gives hope to asthma sufferers. A UCSF researcher and his colleagues believe they have found a way to help asthma sufferers by impeding the two most significant biological responses that lead to an asthma attack.

18 Sep 2012

Scripps Florida scientist receives two grants to focus on sulfenylation

A scientist from the Florida campus of The Scripps Research Institute has been awarded a pair of grants totaling $2.8 million from the National Institute of General Medical Sciences of the National Institutes of Health, and from TargAnox, a Massachusetts-based biotechnology firm.

18 Sep 2012

Brain-healthy lifestyle may prevent symptoms of Alzheimer's

Alzheimer's disease is the sixth leading cause of death in the U.S., and that figure isn't going down. In fact, as America's older population grows, deaths from Alzheimer's continue to rise, and have increased 66 percent since 2000. If current population trends continue and no cure is found, the actual number of people living with the disease could double every 20 years.

18 Sep 2012

Nanoparticles for non-invasive photodynamic therapy of deep cancer

National University of Singapore researchers at the Faculty of Engineering's Department of Bioengineering have discovered a new technology that paves the way for a new safe and non-invasive method of treating deep cancer. Led by Associate Professor Zhang Yong, the team has so far, proven that their technology could inhibit tumour growth and control gene expression in mice. This is a world's first for the use of nanoparticles for non-invasive photodynamic therapy of deep cancer.

17 Sep 2012

MediSapiens launches unified cloud computing application for personalized genomics

MediSapiens launches first-in-kind fully integrated and unified cloud computing application that harnesses the power of Big Data and enables knowledge-based drug discovery and repositioning for personalized genomics.

17 Sep 2012