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Blocked blood vessels linked to familiar signs of aging

Many common signs of aging, such as shaking hands, stooped posture and walking slower, may be due to tiny blocked vessels in the brain that can't be detected by current technology.

2 Sep 2011

Chromatin might have another life as direct signaling molecule

Chromatin - the intertwined histone proteins and DNA that make up chromosomes - constantly receives messages that pour in from a cell's intricate signaling networks: Turn that gene on. Stifle that one. But chromatin also talks back, scientists at The University of Texas MD Anderson Cancer Center report today in the journal Cell, issuing orders affecting a protein that has nothing to do with chromatin's central role in gene transcription - the first step in protein formation.

2 Sep 2011

New genetic screening program for families at high risk of colorectal cancer

UT Southwestern Medical Center has developed a new lifesaving genetic screening program for families at high risk of contracting colorectal cancer, a deadly yet highly preventable form of cancer.

2 Sep 2011

Pemetrexed treatment produces better outcomes in ALK-translocated NSCLC patients

Patients with ALK-rearranged non-small cell lung cancer (NSCLC) responded significantly better to pemetrexed than patients whose cancer did not show ALK translocation, according to research published in the September issue of the Journal of Thoracic Oncology, the official publication of the International Association for the Study of Lung Cancer.

2 Sep 2011

UVA researchers develop 3-D model to visualize early growth of human breast tissue

University of Virginia researchers have developed a revolutionary three-dimensional model that allows them to visualize how breast tissue grows in its earliest stages, giving them the closest look ever at the very beginnings of breast cancer.

2 Sep 2011

Neutrophils linked to growth and spread of cancer

Scripps Research Professor James Quigley, Staff Scientist Elena Deryugina, and colleagues had previously demonstrated that white blood cells known as neutrophils—bone marrow-derived cells that function as "first responders" at sites of acute inflammation—promote the growth of new blood vessels in normal, healthy tissue.

2 Sep 2011

UTHealth Phase I trial: Bone marrow stem cell therapy feasible, safe for acute stroke patients

Using a patient's own bone marrow stem cells to treat acute stroke is feasible and safe, according to the results of a ground-breaking Phase I trial at The University of Texas Health Science Center at Houston.

2 Sep 2011

Special journal edition chronicles 3-D structures of important antibacterial, bioterrorist targets

The September issue of the online scientific journal Acta Crystallographica: Structural Biology and Crystallization Communications (Acta Cryst F) will consist entirely of work done at the Seattle Structural Genomics Center for Infectious Disease (SSGCID), a consortium of researchers from Seattle BioMed, Emerald BioStructures, the University of Washington and Pacific Northwest National Laboratory.

2 Sep 2011

Walnut-containing diet could reduce risk of breast cancer

The risk of breast cancer dropped significantly in mice when their regular diet included a modest amount of walnut, Marshall University researchers report in the journal Nutrition and Cancer.

2 Sep 2011

Ancient antibiotic resistance findings leads experts to stress need to use antibiotics sparingly

"An analysis of 30,000-year-old bacteria whose DNA has been recovered from the Yukon permafrost shows that they were able to resist antibiotics," providing "the first direct evidence that antibiotic resistance is a widespread natural phenomenon that preceded the modern medical use of antibiotics," according to a study in Thursday's issue of the journal Nature, the New York Times reports.

2 Sep 2011

One third of patients with unexplained body malodor production test positive for TMAU

Scientists from the Monell Center report that approximately one third of patients with unexplained body malodor production test positive for the metabolic disorder trimethylaminuria.

2 Sep 2011

Princeton researchers match images of brain activity with complex thought

In an effort to understand what happens in the brain when a person reads or considers such abstract ideas as love or justice, Princeton researchers have for the first time matched images of brain activity with categories of words related to the concepts a person is thinking about. The results could lead to a better understanding of how people consider meaning and context when reading or thinking.

2 Sep 2011

Scientists discover genetic cause of extreme thinness

Scientists have discovered a genetic cause of extreme thinness for the first time, in a study published today in the journal Nature.

2 Sep 2011

People with Alzheimer's have lower ubiquilin-1 protein levels

Researchers have found that a protein variation linked by some genetic studies to Alzheimer's disease is consistently present in the brains of people with Alzheimer's.

2 Sep 2011

Two ALS-associated genes work in tandem to support long-term survival of motor neurons

Although several genes have been linked to amyotrophic lateral sclerosis (ALS), it is still unknown how they cause this progressive neurodegenerative disease. In a new study, Columbia University Medical Center (CUMC) researchers have demonstrated that two ALS-associated genes work in tandem to support the long-term survival of motor neurons.

2 Sep 2011

Dendritic cells play central role in regulation of acetaminophen's toxicity

NYU School of Medicine researchers have discovered that dendritic cells in the liver have a protective role against the toxicity of acetaminophen, the widely used over-the-counter pain reliever and fever reducer for adults and children.

2 Sep 2011

Fibrous stroma can help predict aggressiveness of squamous cell carcinoma

The nature of the connective tissue surrounding lung cancer nests can help predict the aggressiveness of squamous cell carcinoma, according to research published in the September issue of the Journal of Thoracic Oncology, the official publication of the International Association for the Study of Lung Cancer.

2 Sep 2011

CRI announces winners of 2011 Coley Award for distinguished research in tumor immunology

The Cancer Research Institute, Inc. (CRI), a U.S. nonprofit organization established in 1953 to advance the science of tumor immunology and drive the discovery of new cancer immunotherapies, announced today the winners of the 2011 William B. Coley Award for Distinguished Research in Tumor Immunology.

2 Sep 2011

Insight into molecular basis of Enhanced S-Cone Syndrome

A new research report published in The FASEB Journal will help ophthalmologists and scientists better understand a rare genetic disease that causes increased susceptibility to blue light, night blindness, and decreased vision called Enhanced S-Cone Syndrome or Goldman-Favre Syndrome.

2 Sep 2011

Low-cost, portable technique can detect specific proteins in human blood

Blood tests are important diagnostic tools. They accurately tease-out vanishingly small concentrations of proteins and other molecules that help give a picture of overall health or signal the presence of specific diseases. Current testing procedures, however, are expensive and time-consuming, while sophisticated test equipment is bulky and difficult to transport.

2 Sep 2011

Medical Science News

Blocked blood vessels linked to familiar signs of aging

Chromatin might have another life as direct signaling molecule

New genetic screening program for families at high risk of colorectal cancer

Pemetrexed treatment produces better outcomes in ALK-translocated NSCLC patients

UVA researchers develop 3-D model to visualize early growth of human breast tissue

Neutrophils linked to growth and spread of cancer

UTHealth Phase I trial: Bone marrow stem cell therapy feasible, safe for acute stroke patients

Special journal edition chronicles 3-D structures of important antibacterial, bioterrorist targets

Walnut-containing diet could reduce risk of breast cancer

Ancient antibiotic resistance findings leads experts to stress need to use antibiotics sparingly

One third of patients with unexplained body malodor production test positive for TMAU

Princeton researchers match images of brain activity with complex thought

Scientists discover genetic cause of extreme thinness

People with Alzheimer's have lower ubiquilin-1 protein levels

Two ALS-associated genes work in tandem to support long-term survival of motor neurons

Dendritic cells play central role in regulation of acetaminophen's toxicity

Fibrous stroma can help predict aggressiveness of squamous cell carcinoma

CRI announces winners of 2011 Coley Award for distinguished research in tumor immunology

Insight into molecular basis of Enhanced S-Cone Syndrome

Low-cost, portable technique can detect specific proteins in human blood

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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