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Manipulating retinal recipient microenvironment impacts photoreceptor cell transplantation

A research team in the United Kingdom has found that insulin-like growth factor (IGF1) impacts cell transplantation of photoreceptor precursors by manipulating the retinal recipient microenvironment, enabling better migration and integration of the cells into the adult mouse retina.

12 Jul 2012

SLU professor to study how antithrombin might prevent premature death from heart disease

Alireza "Ray" Rezaie, Ph.D., professor of biochemistry and molecular biology at Saint Louis University School of Medicine, has received a $1.52 million NIH grant to study how the key blood clotting inhibitor antithrombin might be exploited to prevent premature death from heart disease.

12 Jul 2012

Scientists assemble timeline of brain changes that lead to Alzheimer's

Scientists have assembled the most detailed chronology to date of the human brain's long, slow slide into full-blown Alzheimer's disease.

12 Jul 2012

Communication between brain and muscle cells is short-lived without LRP4 protein

Communication between the brain and muscle must be strong for us to eat, breathe or walk. Now scientists have found that a protein known to be on the surface of muscle cells must be present in both tissues to ensure the conversation is robust.

12 Jul 2012

BGI, BioMed Central launch GigaScience journal

BGI, the world's largest genome sequencing institute, and their publishing partner BioMed Central, a leader in scientific data sharing, announce the launch of a new journal, GigaScience, which publishes large-scale biological research in a unique format.

12 Jul 2012

Researchers identify set of laboratory-based biomarkers that aid in diagnosis of schizophrenia

In the current online issue of PLoS ONE, researchers at the University of California, San Diego School of Medicine say they have identified a set of laboratory-based biomarkers that can be useful for understanding brain-based abnormalities in schizophrenia. The measurements, known as endophenotypes, could ultimately be a boon to clinicians who sometimes struggle to recognize and treat the complex and confounding mental disorder.

12 Jul 2012

Cellular change also occurs in early-stage lung cancer, say researchers

Cellular change thought to happen only in late-stage cancers to help tumors spread also occurs in early-stage lung cancer as a way to bypass growth controls, say researchers at Mayo Clinic in Florida.

12 Jul 2012

TGen's customized procedure produces high amounts of exosomes for treatment of CKD

Researchers at the Translational Genomics Research Institute (TGen) have developed a method of isolating biospecimens that could lead to a less costly, less invasive and more accurate way of diagnosing chronic kidney disease, or CKD.

12 Jul 2012

Eschar-derived cells may be used for tissue engineering

A research team in the Netherlands has found that cells from burn eschar, the non-viable tissue remaining after burn injury and normally removed to prevent infection, can be a source of mesenchymal cells that may be used for tissue engineering.

12 Jul 2012

Memory-binding process allows people to better understand new concepts and make decisions

When humans learn, their brains relate new information with past experiences to derive new knowledge, according to psychology research from The University of Texas at Austin.

12 Jul 2012

Researchers settle controversy over the mechanism by which silver nanoparticles kill bacteria

Rice University researchers have settled a long-standing controversy over the mechanism by which silver nanoparticles, the most widely used nanomaterial in the world, kill bacteria.

12 Jul 2012

Physiologists, neuropathologists identify origin of cancer metastasis formation

It is not primary tumors that are responsible for the majority of cancer deaths, but rather their metastases. Physiologists and neuropathologists from the University of Zurich have now identified the origin of metastasis formation, thereby becoming the first to reveal the pathway of metastasizing intestinal cancer cells out of the blood stream. The results allow new approaches in the development of cancer therapies.

12 Jul 2012

SRI receives NIAID grant to develop HIV vaccine

The Scripps Research Institute has been awarded a grant expected to total more than $77 million from the National Institutes of Health's (NIH) National Institute of Allergy and Infectious Diseases (NIAID).

12 Jul 2012

New assay can identify rare cancerous cells within mixed populations

Rare cells can be identified within mixed cell populations with near perfect accuracy using a detection technique devised by research teams led by Robert Wieder, MD, PhD, at the University of Medicine and Dentistry of New Jersey-New Jersey Medical School and Rajan Kumar, MD, PhD, at Genome Data Systems in Hamilton, N.J. This technique may facilitate cancer diagnosis, which often relies on the detection of rare cancerous cells in tiny amounts of biopsy tissue or fluid.

12 Jul 2012

Study details how resistance to targeted drug therapy emerges in colorectal cancers

A Harvard researcher studying the evolution of drug resistance in cancer is predicting that, in a few decades, "many, many cancers could be manageable."

12 Jul 2012

Study links brain anatomy and activation with human altruism

What can explain extreme differences in altruism among individuals, from Ebenezer Scrooge to Mother Teresa? It may all come down to variation in the size and activity of a brain region involved in appreciating others' perspectives, according to a study published by Cell Press in the July 12th issue of the journal Neuron. The findings also provide a neural explanation for why altruistic tendencies remain stable over time.

12 Jul 2012

Novel molecular mechanism responsible for most important symptom of major depression

Stanford University School of Medicine scientists have laid bare a novel molecular mechanism responsible for the most important symptom of major depression: anhedonia, the loss of the ability to experience pleasure.

12 Jul 2012

Genes responsible for immune function are almost different in middle age than in early adulthood

Important insights that explain why our ability to ward off infection declines with age are published in a new research report in the July 2012 issue of the Genetics Society of America's journal, GENETICS.

12 Jul 2012

Powerful brain chemical systems work together to paralyze skeletal muscles during REM sleep

Two powerful brain chemical systems work together to paralyze skeletal muscles during rapid eye movement (REM) sleep, according to new research in the July 11 issue of The Journal of Neuroscience. The finding may help scientists better understand and treat sleep disorders, including narcolepsy, tooth grinding, and REM sleep behavior disorder.

12 Jul 2012

Brain anatomy and brain activity connected to altruistic behavior

The volume of a small brain region influences one's predisposition for altruistic behavior. Researchers from the University of Zurich show that people who behave more altruistically than others have more gray matter at the junction between the parietal and temporal lobe, thus showing for the first time that there is a connection between brain anatomy, brain activity and altruistic behavior.

12 Jul 2012

Medical Science News

Manipulating retinal recipient microenvironment impacts photoreceptor cell transplantation

SLU professor to study how antithrombin might prevent premature death from heart disease

Scientists assemble timeline of brain changes that lead to Alzheimer's

Communication between brain and muscle cells is short-lived without LRP4 protein

BGI, BioMed Central launch GigaScience journal

Researchers identify set of laboratory-based biomarkers that aid in diagnosis of schizophrenia

Cellular change also occurs in early-stage lung cancer, say researchers

TGen's customized procedure produces high amounts of exosomes for treatment of CKD

Eschar-derived cells may be used for tissue engineering

Memory-binding process allows people to better understand new concepts and make decisions

Researchers settle controversy over the mechanism by which silver nanoparticles kill bacteria

Physiologists, neuropathologists identify origin of cancer metastasis formation

SRI receives NIAID grant to develop HIV vaccine

New assay can identify rare cancerous cells within mixed populations

Study details how resistance to targeted drug therapy emerges in colorectal cancers

Study links brain anatomy and activation with human altruism

Novel molecular mechanism responsible for most important symptom of major depression

Genes responsible for immune function are almost different in middle age than in early adulthood

Powerful brain chemical systems work together to paralyze skeletal muscles during REM sleep

Brain anatomy and brain activity connected to altruistic behavior

Leveraging the Radian ASAP in standard casework

A journey through science, software, and innovation: Insights from the Bruker software team

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

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