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NOTCH1 signaling promotes T-cell acute lymphoblastic leukemia-initiating cell regeneration

Research suggests that patients with leukemia sometimes relapse because standard chemotherapy fails to kill the self-renewing leukemia initiating cells, often referred to as cancer stem cells. In such cancers, the cells lie dormant for a time, only to later begin cloning, resulting in a return and metastasis of the disease.

3 Jul 2012

Study confirms a rare susceptibility variant in glioma

Researchers at Moffitt Cancer Center working with colleagues at three other institutions have validated a link between a rare genetic variant and the risk of glioma, the most common and lethal type of brain tumor.

3 Jul 2012

Researchers identify new gene target for leukemia therapy

Researchers at the University of Cincinnati (UC) Hoxworth Blood Center have discovered a new gene target for leukemia therapy.

3 Jul 2012

Being a parent protects against cold: Study

Being a parent reduces your risk of catching a cold—possibly because of unknown "psychological or behavioral differences between parents and nonparents," according to a study in the July issue of Psychosomatic Medicine, the official journal of the American Psychosomatic Society.

3 Jul 2012

July issue of Neurosurgery provides update on Human Connectome Project

A research effort called the Human Connectome Project is seeking to explore, define, and map the functional connections of the human brain. An update on progress in and upcoming plans for the Human Connectome Project appears in the July issue of Neurosurgery, official journal of the Congress of Neurological Surgeons.

3 Jul 2012

PGD for breast cancer genes BRCA1/2 is now feasible

Preimplantation genetic diagnosis (PGD) for the breast cancer genes BRCA1/2 is now feasible and established, with good success rates for those treated, according to investigators from the reproduction, oncology and genetics centres of the university hospitals of Maastricht and Brussels.

3 Jul 2012

GRP78 plays an important role in breast cancers that respond to anti-estrogen therapy

Researchers at Georgetown Lombardi Comprehensive Cancer Center have uncovered a single molecule they say is a major determinant of resistance to anti-estrogen therapy used to treat or prevent breast cancer in high-risk women.

3 Jul 2012

Cells close to death from toxin exposure can survive when toxins are removed

The vast majority of cells that appear to be on a one-way track to death after exposure to toxins can bounce back completely after those toxins are removed, Johns Hopkins scientists report in a new study. The finding, published in the June 15 issue of Molecular Biology of the Cell, is not only a testament to the indomitable cellular spirit, but could also offer some practical insight on how to save dying tissues after heart attacks or strokes as well as prevent cancer in cells transiently exposed to toxins.

3 Jul 2012

Study identifies possible new approach to defeat bacterial infections

Research led by St. Jude Children's Research Hospital scientists has identified a possible new approach to defeating bacterial infections by targeting an innate immune system component in a bid to invigorate the immune response.

3 Jul 2012

Osteoarthritis susceptibility: eight potential genes discovered

The largest genome-wide association study (GWAS) of osteoarthritis to date, published Online First in The Lancet, has uncovered eight new genetic variants or loci that appear to increase susceptibility to the most common form of arthritis, which affects about 40% of the world population older than 70 years. These findings bring the total number of osteoarthritis susceptibility genes isolated in European populations to 11.

3 Jul 2012

GHB binds to GABAA-receptor in the brain under physiologically relevant conditions

Researchers are closer to understanding the biology behind GHB, a transmitter substance in the brain, best known in its synthetic form as the illegal drug fantasy. These findings have just been published in the scientific journal PNAS.

3 Jul 2012

$Researchers report positive effects of ibuprofen on bone repair after fracture or surgery$

Researchers report positive effects of ibuprofen on bone repair after fracture or surgery

A study conducted at the University of Granada has demonstrated that ibuprofen -a non-steroidal anti-inflammatory drug (NSAID)- has beneficial effects on bone repair after a fracture or following bone surgery.

3 Jul 2012

Women with higher intake of dietary saturated fats have fewer mature oocytes available for IVF

Women with a higher intake of dietary saturated fats have fewer mature oocytes available for collection in IVF, according to results of a study from the Harvard School of Public Health funded by the US National Institutes of Health.

3 Jul 2012

Changing tissue landscape promotes higher cancer rates in the elderly

Cancers are age-related, much more frequent in the old than in the young. A University of Colorado Cancer Center review published today in the journal Oncogene argues against the conventional wisdom that the accumulation of cancer-causing mutations leads to more cancer in older people, instead positing that it is the changing features of tissue in old age that promote higher cancer rates in the elderly.

3 Jul 2012

Imaging PR status may help identify tumor response to endocrine therapy

Research published in the July issue of The Journal of Nuclear Medicine shows imaging progesterone receptor (PR) status also may be able to identify responders and nonresponders to endocrine therapy at an early stage.

3 Jul 2012

Scientists discover Eya1 enzyme control of pulmonary barrier integrity

Scientists have provided the first evidence that an enzyme called Eya1 protein phosphatase is a critical regulator of lung function and that this may have broad implications for sufferers of a variety of pulmonary diseases.

3 Jul 2012

Study demonstrates effectiveness of combination therapy for breast cancer cells in vitro

A study conducted at Boston University School of Medicine (BUSM) demonstrates an effective combination therapy for breast cancer cells in vitro.

3 Jul 2012

ASU professor to receive $6.25M basic research award under DoD's MURI program

Arizona State University professor Hao Yan, an innovator in the field of nanotechnology, has been selected to receive a five-year, $6.25 million basic research award under the Department of Defense's (DoD) Multidisciplinary University Research Initiative (MURI) program.

3 Jul 2012

Researchers show how aggressive form of multiple myeloma resists chemotherapy

Researchers at Washington University School of Medicine in St. Louis have shown how an aggressive form of multiple myeloma resists chemotherapy.

3 Jul 2012

Scientists assemble string of genetic letters that could control parrots' vocal learning

Scientists say they have assembled more completely the string of genetic letters that could control how well parrots learn to imitate their owners and other sounds.

3 Jul 2012

Medical Science News

NOTCH1 signaling promotes T-cell acute lymphoblastic leukemia-initiating cell regeneration

Study confirms a rare susceptibility variant in glioma

Researchers identify new gene target for leukemia therapy

Being a parent protects against cold: Study

July issue of Neurosurgery provides update on Human Connectome Project

PGD for breast cancer genes BRCA1/2 is now feasible

GRP78 plays an important role in breast cancers that respond to anti-estrogen therapy

Cells close to death from toxin exposure can survive when toxins are removed

Study identifies possible new approach to defeat bacterial infections

Osteoarthritis susceptibility: eight potential genes discovered

GHB binds to GABAA-receptor in the brain under physiologically relevant conditions

Researchers report positive effects of ibuprofen on bone repair after fracture or surgery

Women with higher intake of dietary saturated fats have fewer mature oocytes available for IVF

Changing tissue landscape promotes higher cancer rates in the elderly

Imaging PR status may help identify tumor response to endocrine therapy

Scientists discover Eya1 enzyme control of pulmonary barrier integrity

Study demonstrates effectiveness of combination therapy for breast cancer cells in vitro

ASU professor to receive $6.25M basic research award under DoD's MURI program

Researchers show how aggressive form of multiple myeloma resists chemotherapy

Scientists assemble string of genetic letters that could control parrots' vocal learning

Leveraging the Radian ASAP in standard casework

A journey through science, software, and innovation: Insights from the Bruker software team

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

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