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New insight on ability of certain PAH-derived lesions to evade DNA repair machinery

A person doesn't have to go far to find a polycyclic aromatic hydrocarbon (PAH). These carcinogen precursors are inhaled through automobiles exhaust during the morning commute, are present in a drag of cigarette smoke, and are part of any barbequed meal.

4 Nov 2012

First study to measure minute changes in breast tumor connective tissue fibers

Using advanced microscopes equipped with tissue-penetrating laser light, cancer imaging experts at Johns Hopkins have developed a promising, new way to accurately analyze the distinctive patterns of ultra-thin collagen fibers in breast tumor tissue samples and to help tell if the cancer has spread.

3 Nov 2012

Two research groups present data on Pressure BioSciences' PCT Platform at HUPO 2012

Pressure BioSciences, Inc. today announced that scientists from two separate research groups presented data at the recent HUPO 11th Annual World Congress (Boston, MA) indicating that the incorporation of the Company's Pressure Cycling Technology Platform into their sample preparation processes resulted in a marked improvement in the quality and/or efficiency of test results.

3 Nov 2012

Caltech-led team discovers enzyme responsible for neural crest cell development

During the early developmental stages of vertebrates-animals that have a backbone and spinal column, including humans-cells undergo extensive rearrangements, and some cells migrate over large distances to populate particular areas and assume novel roles as differentiated cell types.

3 Nov 2012

Weill Cornell researchers awarded Grand Challenges Explorations grants

Weill Cornell Medical College announced today that it is a Grand Challenges Explorations winner, an initiative funded by the Bill & Melinda Gates Foundation.

3 Nov 2012

Scientists decipher the brain's code for visual working memory in monkeys

The brain holds in mind what has just been seen by synchronizing brain waves in a working memory circuit, an animal study supported by the National Institutes of Health suggests. The more in-sync such electrical signals of neurons were in two key hubs of the circuit, the more those cells held the short-term memory of a just-seen object.

3 Nov 2012

New tool can particularly sort tumor-causing cancer cells

A new tool developed by scientists at The Methodist Hospital separates tumor-causing cancer cells from more benign cells by subjecting the cells to a microscopic game of Plinko -- except only the squishiest cells make it through.

3 Nov 2012

UC Santa Barbara reports key discovery in interdisciplinary study of split-brain research

UC Santa Barbara has reported an important discovery in the interdisciplinary study of split-brain research. The findings uncover dynamic changes in brain coordination patterns between left and right hemispheres.

3 Nov 2012

MED1 plays a central role in mediating tamoxifen resistance in breast cancer

A University of Cincinnati (UC) cancer biology team reports breakthrough findings about specific cellular mechanisms that may help overcome endocrine (hormone) therapy-resistance in patients with estrogen-positive breast cancers, combating a widespread problem in effective medical management of the disease.

3 Nov 2012

WSU researcher receives NSF fund to study on antibiotic resistance

In March, the director-general of the World Health Organization warned of "an end to modern medicine as we know it."

3 Nov 2012

Researchers develop new technique to predict enzymes known to accelerate diseases

Predicting how atherosclerosis, osteoporosis or cancer will progress or respond to drugs in individual patients is difficult.

3 Nov 2012

Cannabis use causes temporary cognitive breakdown in non-psychotic individuals: Study

Researchers at the University of Bergen in Norway have found new support for their theory that cannabis use causes a temporary cognitive breakdown in non-psychotic individuals, leading to long-term psychosis.

3 Nov 2012

CIBMTR renews Stem Cell Therapeutics Outcomes Database contract with HRSA

The Medical College of Wisconsin Center for International Blood and Marrow Transplant Research successfully competed for, and was awarded, renewal of the Stem Cell Therapeutics Outcomes Database contract with the U.S. Health Resources and Services Administration.

3 Nov 2012

New partnership to make advancements in personalized breast cancer treatment and care

The Edith Sanford Breast Cancer Foundation and The Scripps Research Institute today announced the formation of a dynamic partnership that will lay the groundwork for lifesaving advancements in personalized breast cancer treatment and care.

3 Nov 2012

Scientists find new way to unlock cells' destinies

Scientists have discovered that breaking a biological signaling system in an embryo allows them to change the destiny of a cell.

3 Nov 2012

Adding angiogenesis inhibitor to anti-HER2 drugs extends survival in mice with breast cancer

Adding an angiogenesis inhibitor to treatment with a HER2-inhibiting drug could improve outcomes for patients with HER2-positive breast cancer who develop brain metastases. In their report published online in PNAS Plus, Massachusetts General Hospital (MGH) investigators report the first preclinical study combining antiangiogenic and anti-HER2 drugs in an animal model of brain metastatic breast cancer.

3 Nov 2012

Scientists sequence and analyze human genomes to discover many variants

Thanks to powerful computational tools developed at Simon Fraser University, more than 100 scientists from around the world have genetically mapped the largest and most varied number of human genomes to date.

3 Nov 2012

Mass spectrometry can help visualize how drugs work inside living cells to kill infectious microbes

Weill Cornell Medical College researchers report that mass spectrometry, a tool currently used to detect and measure proteins and lipids, can also now allow biologists to "see" for the first time exactly how drugs work inside living cells to kill infectious microbes.

3 Nov 2012

Studies show standardizing computer programs help improve genetic testing for Lynch Syndrome

Many patients who have genetic testing for Lynch syndrome, a hereditary predisposition to colon cancer, receive the inconclusive result "variants of uncertain clinical significance."

3 Nov 2012

Researcher identifies 71 genetic regions newly associated with inflammatory bowel disease

In one of the largest studies of its kind ever conducted, an international team of scientists has thrown new light on the genetic basis of the inflammatory bowel diseases (IBD).

3 Nov 2012

Medical Science News

New insight on ability of certain PAH-derived lesions to evade DNA repair machinery

First study to measure minute changes in breast tumor connective tissue fibers

Two research groups present data on Pressure BioSciences' PCT Platform at HUPO 2012

Caltech-led team discovers enzyme responsible for neural crest cell development

Weill Cornell researchers awarded Grand Challenges Explorations grants

Scientists decipher the brain's code for visual working memory in monkeys

New tool can particularly sort tumor-causing cancer cells

UC Santa Barbara reports key discovery in interdisciplinary study of split-brain research

MED1 plays a central role in mediating tamoxifen resistance in breast cancer

WSU researcher receives NSF fund to study on antibiotic resistance

Researchers develop new technique to predict enzymes known to accelerate diseases

Cannabis use causes temporary cognitive breakdown in non-psychotic individuals: Study

CIBMTR renews Stem Cell Therapeutics Outcomes Database contract with HRSA

New partnership to make advancements in personalized breast cancer treatment and care

Scientists find new way to unlock cells' destinies

Adding angiogenesis inhibitor to anti-HER2 drugs extends survival in mice with breast cancer

Scientists sequence and analyze human genomes to discover many variants

Mass spectrometry can help visualize how drugs work inside living cells to kill infectious microbes

Studies show standardizing computer programs help improve genetic testing for Lynch Syndrome

Researcher identifies 71 genetic regions newly associated with inflammatory bowel disease

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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