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Proteins detected in urine may enable diagnosis of Kawasaki disease

A set of proteins detected in urine by researchers at Boston Children's Hospital may prove to be the first biomarkers for Kawasaki disease, an uncommon but increasingly prevalent disease which causes inflammation of blood vessels that can lead to enlarged coronary arteries and even heart attacks in some children.

20 Dec 2012

FUS RNA binding ability essential for development of Amyotrophic Lateral Sclerosis

Research led by Dr. Udai Pandey, Assistant Professor of Genetics at LSU Health Sciences Center New Orleans, has found that the ability of a protein made by a gene called FUS to bind to RNA is essential to the development of Amyotrophic Lateral Sclerosis (ALS). This discovery identifies a possible therapeutic target for the fatal neurological disease.

20 Dec 2012

Scientists succeed in organising synthetic and biological nanoparticles into crystalline materials

Scientists from Aalto University, Finland, have succeeded in organising virus particles, protein cages and nanoparticles into crystalline materials. These nanomaterials studied by the Finnish research group are important for applications in sensing, optics, electronics and drug delivery.

20 Dec 2012

V-chip could allow health care providers to do 50 different tests in one go

A new device about the size of a business card could allow health care providers to test for insulin and other blood proteins, cholesterol, and even signs of viral or bacterial infection all at the same time—with one drop of blood. Preliminary tests of the V-chip, created by scientists at The Methodist Hospital Research Institute and MD Anderson Cancer Center, were published last night by Nature Communications.

20 Dec 2012

Study focuses on hormone-sensitive breast tumours

Gene expression in breast cancer provides valuable biological information for better determining the diagnosis, treatment, risk of relapse and survival rate. However, the most common form of characterizing breast cancer is by histopathological techniques. This study, headed by Dr Aleix Prat, Head of the Translational Genomics Group at the Vall d'Hebron Institute of Oncology (VHIO) and an oncologist at the Breast Cancer Unit of the Vall d´Hebron University Hospital, focused on hormone-sensitive breast tumours known as luminals.

20 Dec 2012

Researchers report seroprevalence of three avian flu virus strains in pigs in southern China

Researchers report for the first time the seroprevalence of three strains of avian influenza viruses in pigs in southern China, but not the H5N1 avian influenza virus. Their research, published online ahead of print in the Journal of Clinical Microbiology, has implications for efforts to protect the public health from pandemics.

20 Dec 2012

Scientists uncover TDP-43 protein as possible target for treatment of ALS, FTD

Neuroscientists at Georgetown University Medical Center say they have new evidence that challenges scientific dogma involving two fatal neurodegenerative diseases - amyotrophic lateral sclerosis (ALS), and frontotemporal dementia (FTD) - and, in the process, have uncovered a possible therapeutic target as a novel strategy to treat both disorders.

20 Dec 2012

Researcher explores new PCR system to discover dangerous foodborne pathogens

Pina Fratamico is on the quest to find the easiest and fastest way to test for harmful Escherichia coli in ground beef. In an article published in Frontiers in Microbiology on the 20th of December, she explores using a next-generation real-time polymerase chain reaction (PCR) system to discover specific gene targets that indicate the presence of dangerous foodborne pathogens. The results show that assays performed using this PCR system are rapid, sensitive, and reliable.

20 Dec 2012

New clues in understanding how epithelial cells repair themselves following chlorine-related injury

Scarring of the airways can lead to long-term breathing problems for some people exposed to high levels of chlorine gas from events such as an industrial accident, chemical spill following a train derailment or terroristic chemical warfare. Household mishaps from mixing bleach with acidic cleaning products also can cause release of chlorine gas; if this occurs in a poorly ventilated space, chlorine levels could be high enough to cause lung injury.

20 Dec 2012

GI bacteria exert some control over their hosts' appetites: Review

Over the last half decade, it has become increasingly clear that the normal gastrointestinal (GI) bacteria play a variety of very important roles in the biology of human and animals. Now Vic Norris of the University of Rouen, France, and coauthors propose yet another role for GI bacteria: that they exert some control over their hosts' appetites.

20 Dec 2012

West African human population genomes provide important clues about evolution of HIV

Human immunodeficiency virus (HIV) may have affected humans for much longer than is currently believed. Alfred Roca, an assistant professor in the College of Agricultural, Consumer and Environmental Sciences at the University of Illinois, thinks that the genomes of an isolated West African human population provide important clues about how the disease has evolved.

20 Dec 2012

Investigators report non-coding miRNAs as appealing biomarkers for cancer malignancy

As many as 50 percent of all human protein-coding genes are regulated by microRNA (miRNA) molecules. While some miRNAs impact onset and progression of cancer, others can actually suppress the development of malignant tumors and are useful in cancer therapy. They can also serve as potential biomarkers for early cancer detection. In a new issue of Cancer Biomarkers, investigators report on non-coding miRNAs as appealing biomarkers for malignancy.

20 Dec 2012

Scientists map sensory nerves in mouse skin

Johns Hopkins scientists have created stunning images of the branching patterns of individual sensory nerve cells. Their report, published online in the journal eLife on Dec. 18, details the arrangement of these branches in skin from the backs of mice.

20 Dec 2012

Link made between muscular dystrophy and defective nerve wiring

Working with mice, Johns Hopkins scientists have discovered that a particular protein helps nerve cells extend themselves along the spinal cord during mammalian development. Their results shed light on the subset of muscular dystrophies that result from mutations in the gene that holds the code for the protein, called dystroglycan, and also show how the nerve and muscle failings of the degenerative diseases are related.

20 Dec 2012

Study helps reveal how nervous system modulates motor control patterns

Most people are impressed by how a toad jumps. UC Irvine biologist Emanuel Azizi is more impressed by how one lands. An assistant professor of ecology & evolutionary biology who specializes in muscle physiology and biomechanics, Azizi found that nature's favorite leapers possess a neuromuscular response that's specific to the intensity of a landing - a mechanism that protects muscles from injury upon impact.

20 Dec 2012

Researchers reveal role of dendritic cells in Type 1 diabetes

The researchers reveal the role of the innate immune cells, especially the dendritic cells, that cause the activation of the killer T-lymphocytes whose action is directed against the p pancreatic cells. The results obtained in mice make it possible to consider new ways of regulating the auto-immune reaction generated by the innate immune cells.

20 Dec 2012

Lou Gehrig's disease may be treatable using neural stem cells

Promising new research provides evidence that ALS, amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, may be treatable using neural stem cells.

20 Dec 2012

Genomic technology revolutionizes gene discovery and disease understanding in autism

Genomic technology has revolutionized gene discovery and disease understanding in autism, according to an article published in the December 20 issue of the journal Neuron.

20 Dec 2012

SR9238 compound can reverse effects of fatty liver disease

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have developed the first synthetic compound that can reverse the effects of a serious metabolic condition known as fatty liver disease. True to its name, the disease involves an abnormal buildup of fat in the liver.

20 Dec 2012

Researchers uncover mechanism that switches off cell transport regulating proteins

Researchers at the RUB and from the MPI Dortmund have uncovered the mechanism that switches off the cell transport regulating proteins. They were able to resolve in detail how the central switch protein Rab is down-regulated with two "protein fingers" by its interaction partners.

20 Dec 2012

Medical Science News

Proteins detected in urine may enable diagnosis of Kawasaki disease

FUS RNA binding ability essential for development of Amyotrophic Lateral Sclerosis

Scientists succeed in organising synthetic and biological nanoparticles into crystalline materials

V-chip could allow health care providers to do 50 different tests in one go

Study focuses on hormone-sensitive breast tumours

Researchers report seroprevalence of three avian flu virus strains in pigs in southern China

Scientists uncover TDP-43 protein as possible target for treatment of ALS, FTD

Researcher explores new PCR system to discover dangerous foodborne pathogens

New clues in understanding how epithelial cells repair themselves following chlorine-related injury

GI bacteria exert some control over their hosts' appetites: Review

West African human population genomes provide important clues about evolution of HIV

Investigators report non-coding miRNAs as appealing biomarkers for cancer malignancy

Scientists map sensory nerves in mouse skin

Link made between muscular dystrophy and defective nerve wiring

Study helps reveal how nervous system modulates motor control patterns

Researchers reveal role of dendritic cells in Type 1 diabetes

Lou Gehrig's disease may be treatable using neural stem cells

Genomic technology revolutionizes gene discovery and disease understanding in autism

SR9238 compound can reverse effects of fatty liver disease

Researchers uncover mechanism that switches off cell transport regulating proteins

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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