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Analysis of Cerebrospinal Fluid Biomarkers may help early detection of Alzheimer´S Disease

Analysis of specific biomarkers in a cerebrospinal fluid sample can differentiate patients with Alzheimer's disease from those with other types of dementia. The method, which is being studied by researchers at Sahlgrenska Academy, may eventually permit earlier detection of Alzheimer's disease.

22 Oct 2012

Researchers discover Hyalomma ticks in migratory birds

A type of haemorrhagic fever (Crimean-Congo) that is prevalent in Africa, Asia, and the Balkans has begun to spread to new areas in southern Europe. Now Swedish researchers have shown that migratory birds carrying ticks are the possible source of contagion.

22 Oct 2012

Insight into calcium pumps in cells

When animals and plants are exposed to influences such as bacterial attack, odour and cold, calcium ions flow into the cells. The calcium provides the cells with a signal about what is going on outside, but as high concentrations of calcium are toxic to the cells, it must be quickly pumped out again.

22 Oct 2012

Cobinamide may help reverse effects of cyanide toxicity

Smoke inhalation is the major cause of death in fire victims due to cyanide poisoning. However, new research presented at CHEST 2012, the annual meeting of the American College of Chest Physicians, shows that a new antidote, cobinamide, may help reverse the effects of cyanide toxicity.

22 Oct 2012

VEGF produced by NPCs plays a strong role in influencing microglial behavior

The brain's key "breeder" cells, it turns out, do more than that. They secrete substances that boost the numbers and strength of critical brain-based immune cells believed to play a vital role in brain health. This finding adds a new dimension to our understanding of how resident stem cells and stem cell transplants may improve brain function.

22 Oct 2012

Fungal exposure in homes could increase risk of sarcoidosis

People who are exposed to mold in their homes could be at an increased risk for sarcoidosis, a chronic inflammatory lung disease. Researchers from Sweden and Slovenia tested 62 nonsmoking patients with sarcoidosis, 34 of whom had extrapulmonary manifestations (EPM).

22 Oct 2012

Pediatric ICU patients often receive off-label drug treatments

"Off label" drugs are medications that have not been tested for safety or efficacy for a specific patient age or condition. New research presented Oct. 21 at the American Academy of Pediatrics (AAP) National Conference and Exhibition in New Orleans found that off-label treatments were ordered for 96 percent of all pediatric patients, and 100 percent of patients ages 13-17, in the intensive care unit of an urban children's hospital.

22 Oct 2012

Research team identifies turbo switch in the vital calcium pump in our body's cells

A Danish-British research team has discovered a turbo switch in the vital calcium pump in our body's cells. In studies at the X-ray source DORIS at Deutsches Elektronen-Synchrotorn DESY in Hamburg and the European Synchrotron Radiation Facility ESRF in Grenoble the team discovered that the on-off switch of the pump has a previously unknown third position, which switches the pump into a turbo gear.

22 Oct 2012

Epigenetic alteration associated with increased risk of breast cancer

Monozygotic twins have the same genome, that is, the same DNA molecule in both siblings. Despite being genetically identical, both twins may have different diseases at different times. This phenomenon is called "twin discordance". But how can people who have the same genetic sequence present different pathologies and at different ages? The explanation partly lies in the fact that the chemical signals added in the DNA to "switch off" or "switch on" genes can be different. These signals are known as epigenetic marks.

20 Oct 2012

Closer to engineering new kidney tissue

With a worldwide shortage of kidneys for patients who need kidney transplants, researchers are diligently working to find ways to engineer new kidney tissue from a patient's own cells or another source. They've come a step closer to realizing that goal with a breakthrough described in an upcoming Journal of the American Society of Nephrology (JASN) study.

20 Oct 2012

Studies explore mechanisms linked to self-control

Converging scientific evidence - not to mention a great deal of life experience - tells us that self-control is an important ability. It helps us keep our cool, get things done, and resist the things that tempt us. Scientists believe that gaining a clearer understanding of how self-control works could provide critical insights into addressing some of the large-scale problems facing society today, including obesity and addiction.

20 Oct 2012

Leaders come together to discuss latest advances in neurosciences

Stony Brook Medicine's Neurosciences Institute brings together leaders in the field of neurosciences to present the latest advances in research and clinical care for neurodegenerative disorders, neuropsychiatric disorders, and neuro-ophthalmology.

20 Oct 2012

UCI, Brown work advances quest for novel treatments for inherited disorder

UC Irvine and Brown University researchers have created a new fruit fly model of inherited epilepsy that's providing insights into the mechanisms underlying temperature-dependent seizures while establishing a platform from which to develop therapies for these disorders.

20 Oct 2012

Researchers identify how mosquito's immune system attacks specific infections

Researchers at the Johns Hopkins Bloomberg School of Public Health have determined a new mechanism by which the mosquitoes' immune system can respond with specificity to infections with various pathogens, including the parasite that causes malaria in humans, using one single gene.

20 Oct 2012

Scientists build first atlas of white-matter microstructure in human brain

A European team of scientists have built the first atlas of white-matter microstructure in the human brain. The project's final results have the potential to change the face of neuroscience and medicine over the coming decade.

20 Oct 2012

AMP report provides overview of next generation sequencing technology

The Association for Molecular Pathology published the report of the Whole Genome Analysis Working Group of the AMP Clinical Practice Committee in the November 2012 issue of The Journal of Molecular Diagnostics.

20 Oct 2012

R848 chemical can prime the immune system to fight lymphoma

UK scientists hope that lymphoma patients could benefit from a new drug that triggers the cancer-fighting properties of the body's own immune system, after highly promising early laboratory results.

From The University of Manchester 20 Oct 2012

Researchers identify crucial stage in the lifecycle of simple viruses

Researchers at the University of Leeds have identified a crucial stage in the lifecycle of simple viruses like polio and the common cold that could open a new front in the war on viral disease.

20 Oct 2012

Study reveals key chemical process that corrects potential visual errors in low-light conditions

On the road at night or on a tennis court at dusk, the eye can be deceived. Vision is not as sharp as in the light of day, and detecting a bicyclist on the road or a careening tennis ball can be tough.

20 Oct 2012

Dartmouth neurobiologist investigates brain's nerve cells that establish one's location and direction

The Who asked "who are you?" but Dartmouth neurobiologist Jeffrey Taube asks "where are you?" and "where are you going?" Taube is not asking philosophical or theological questions. Rather, he is investigating nerve cells in the brain that function in establishing one's location and direction.

20 Oct 2012