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Scientists study a botanical formula that kills aggressive prostate cancer tumors

Scientists at Indiana University, Methodist Research Institute study a botanical formula that kills aggressive prostate cancer tumors. Their findings, based on experiments in mice using a human prostate cancer tumor model, appear online in The International Journal of Oncology.

9 Feb 2012

LFA announces new grants for critical areas of lupus research

Today, the Lupus Foundation of America (LFA) announced new research grants awarded to fund critical areas of research where gaps exist in the understanding and knowledge of lupus including: pediatric lupus, cutaneous (skin) lupus, mid-to-late stage translational research, adult stem cells, and neuropsychiatric lupus, which affects the brain and nervous system.

9 Feb 2012

Conventional method has minimal role in determination of PJI

In their search for new, better ways to diagnose periprosthetic joint infection, Rothman Institute at Jefferson researchers have discovered that measurement of C-reactive protein in the synovial fluid is extremely accurate, while measuring a patients- serum white blood cell count (WBC) and the percentage of neutrophils (PMN%), the conventional method for diagnosis, has a minimal role in the determination of PJI.

9 Feb 2012

New, more targeted way to stimulate neurons in the brain

By harnessing quantum dots—tiny light-emitting semiconductor particles a few billionths of a meter across—researchers at the University of Washington (UW) have developed a new and vastly more targeted way to stimulate neurons in the brain.

9 Feb 2012

Deep-brain stimulation of entorhinal cortex can strengthen memory

Ever gone to the movies and forgotten where you parked the car? New UCLA research may one day help you improve your memory.

9 Feb 2012

Mary Ann Liebert to launch BioResearch Open Access in March

BioResearch Open Access, a new bimonthly peer-reviewed open access journal, will launch in March 2012 by Mary Ann Liebert, Inc., publishers.

9 Feb 2012

Study implicates 'arms race' between genes and germs

Biologists have found new evidence of why mice, people and other vertebrate animals carry thousands of varieties of genes to make immune-system proteins named MHCs--even though some of those genes make vertebrate animals susceptible to infections and to autoimmune diseases.

9 Feb 2012

Thumb and little finger react faster than the middle finger

The fingers on the outside - i.e. the thumb and little finger - therefore react faster than the middle finger, which is exposed to the "cross fire" of two neighbours on each side. Through targeted learning, this speed handicap can be compensated. The working group led by PD Dr. Hubert Dinse (Neural Plasticity Lab at the Institute for Neuroral Computation) report in the current issue of PNAS.

8 Feb 2012

A critical step forward in understanding how insulin secretion is regulated in the body

In a study published last week in the prestigious Proceedings of the National Academy of Sciences of the United States of America, a team led by Dr. Vincent Poitout of the University of Montreal Hospital Research Centre (CRCHUM) has made an important step forward in understanding how insulin secretion is regulated in the body.

8 Feb 2012

Researchers discover function and expression of CD97 in malignant gliomas

Researchers at Virginia Commonwealth University Medical Center's VCU Massey Cancer Center and Harold F. Young Neurosurgical Center and Old Dominion University have discovered that suppression of Wilms tumor 1 protein (WT1) results in downregulation of CD97 gene expression in three glioblastoma cell lines and reduces the characteristic invasiveness exhibited by glial tumor cells.

8 Feb 2012

MRI techniques can measure changes in microstructural properties of white matter

Innovative magnetic resonance imaging (MRI) techniques that can measure changes in the microstructure of the white matter likely to affect brain function and the ability of different regions of the brain to communicate are presented in an article in the groundbreaking new neuroscience journal Brain Connectivity, a bimonthly peer-reviewed publication from Mary Ann Liebert, Inc.

8 Feb 2012

Scientists reveal how psychostimulant drugs work to control hyperactivity

It has long been known that psychostimulant drugs have the paradoxical effect of reducing hyperactivity. [Psychostimulant drugs include methylphenidate - known by the trade names Ritalin, Concerta, and Methylin - and methamphetamine]. Since the mid-1950s, millions of children and adults have been prescribed stimulant medications to control attention deficit hyperactivity disorder.

8 Feb 2012

Researchers discover how mutations in parkin gene cause PD

Parkinson's disease researchers at the University at Buffalo have discovered how mutations in the parkin gene cause the disease, which afflicts at least 500,000 Americans and for which there is no cure.

8 Feb 2012

New skin fillers and laser technologies can correct signs of aging

As we age, our skin undergoes a number of changes affecting its texture, volume and appearance. Fortunately, dermatologists can use fillers or lasers to correct the most notable signs of aging and can recommend skin care products with added ingredients that can further repair damaged skin.

8 Feb 2012

Scientists discover how individual MST neurons function

When you are about to collide into something and manage to swerve away just in the nick of time, what exactly is happening in your brain? A new study from the Montreal Neurological Institute and Hospital - The Neuro, McGill University shows how the brain processes visual information to figure out when something is moving towards you or when you are about to head into a collision.

8 Feb 2012

Researchers discover molecules that differentiate early-stage breast tumors from invasive cancer

Researchers have discovered a restricted pattern of molecules that differentiate early-stage breast tumors from invasive, life-threatening cancer. They also found a similar molecular signature that correlated with the aggressiveness of invasive tumors, and with the time to metastasis and overall survival.

8 Feb 2012

New immunotherapy combination prolongs survival in dogs with NHL

A new immunotherapy for companion dogs with advanced-stage non-Hodgkin lymphoma (NHL) has been shown to improve survival while maintaining quality of life, according to a study published in the journal Scientific Reports.

8 Feb 2012

Study describes molecular pathway that controls rest and activity rhythms

The molecular pathway that carries time-of-day signals from the body's internal clock to ultimately guide daily behavior is like a black box, says Amita Sehgal, PhD, the John Herr Musser Professor of Neuroscience and Co-Director, Comprehensive Neuroscience Center, at the Perelman School of Medicine, University of Pennsylvania.

8 Feb 2012

Study examines dimensional structure linked with DSM antisocial personality disorder criteria

With no lab tests to guide the clinician, psychiatric diagnostics is challenging and controversial. Antisocial personality disorder is defined as "a pervasive pattern of disregard for, and violation of, the rights of others that begins in childhood or early adolescence and continues into adulthood," according to the fourth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) of the American Psychiatric Association.

8 Feb 2012

Researchers learn how to improve performance of microcantilever sensors

Researchers have learned how to improve the performance of sensors that use tiny vibrating microcantilevers to detect chemical and biological agents for applications from national security to food processing.

8 Feb 2012