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Established human embryonic cell lines vary from newly derived stem cell lines

Established human embryonic cell lines, including those approved for federal research funding under former President George W. Bush, are different than newly derived human embryonic stem cell lines, according to a study by UCLA stem cell researchers.

2 Dec 2011

Northwestern researchers receive NIAMSD grant to study scleroderma

Northwestern Medicine researchers have received two five-year grants totaling $953,000 from the National Institutes of Health's (NIH) National Institute of Arthritis and Musculoskeletal and Skin Diseases to study scleroderma, an autoimmune disease for which there currently is no cure.

2 Dec 2011

New method reveals complete set of aberrant signaling pathways that give rise to cancers

One major obstacle in the fight against cancer is that anticancer drugs often affect normal cells in addition to tumor cells, resulting in significant side effects. Yet research into development of less harmful treatments geared toward the targeting of specific cancer-causing mechanisms is hampered by lack of knowledge of the molecular pathways that drive cancers in individual patients.

2 Dec 2011

Specific electromagnetic fields can block cancer cell growth

New evidence by University of Alabama at Birmingham researchers that specific electromagnetic fields can safely block the proliferation of cancer cells and tumor growth may help refine a new, targeted therapy without any collateral damage.

2 Dec 2011

Mutation on surface of human red blood cells provides protection against vivax malaria

A mutation on the surface of human red blood cells provides protection against malaria caused by the parasite Plasmodium vivax, research led by Case Western Reserve University School of Medicine shows.

2 Dec 2011

Agilent expands life sciences business with two strategic acquisitions

Agilent Technologies Inc. today announced it is expanding its life sciences business with two strategic acquisitions.

2 Dec 2011

Researchers discover how distant satellite cells could help repair damaged muscles

When a muscle is damaged, dormant adult stem cells called satellite cells are signaled to "wake up" and contribute to repairing the muscle. University of Missouri researchers recently found how even distant satellite cells could help with the repair, and are now learning how the stem cells travel within the tissue.

2 Dec 2011

Researchers identify cancer cell mitochondria as 'Achilles' heel' of tumor growth

Researchers at the Kimmel Cancer Center at Jefferson have identified cancer cell mitochondria as the unsuspecting powerhouse and "Achilles' heel" of tumor growth, opening up the door for new therapeutic targets in breast cancer and other tumor types.

2 Dec 2011

Life as a couch potato can create new fat in fat cells

Conventional wisdom says that exercise is a key to weight loss - a no-brainer. But now, Tel Aviv University researchers are revealing that life as a couch potato, stretched out in front of the TV, can actually be "active inactivity" - and cause you to pack on the pounds.

2 Dec 2011

Body's surveillance for cancer causing damage and response to allergies share common pathway

CANCER RESEARCH UK scientists have found that the body's surveillance for cancer causing damage and its response to allergies share a common pathway, according to research published in Science on Thursday.

1 Dec 2011

Insights into causes of Idiopathic Pulmonary Fibrosis

Tracking individual cells within the lung as they move around and multiply has given Duke University researchers new insights into the causes of Idiopathic Pulmonary Fibrosis (IPF) a disease which can only be treated now by lung transplantation.

1 Dec 2011

Enrollment complete in Ceregene's CERE-120 Phase 2b trial for Parkinson's

Ceregene, Inc. reported today that it has completed enrollment in its Phase 2b trial of CERE-120, a gene therapy product expressing the neurturin (NRTN) gene for the treatment of Parkinson's disease.

1 Dec 2011

Yale researchers monitor growth of laboratory-engineered blood vessels after implantation

Using magnetic resonance imaging (MRI) and nanoparticle technology, researchers from Yale have devised a way to monitor the growth of laboratory-engineered blood vessels after they have been implanted in patients. This advance represents an important step toward ensuring that blood vessels, and possibly other tissues engineered from a patient's own biological material, are taking hold and working as expected.

1 Dec 2011

Study presents high-resolution genome-wide p53-binding map for normal human cells

Scientists investigating the interactions, or binding patterns, of a major tumor-suppressor protein known as p53 with the entire genome in normal human cells have turned up key differences from those observed in cancer cells. The distinct binding patterns reflect differences in the chromatin (the way DNA is packed with proteins), which may be important for understanding the function of the tumor suppressor protein in cancer cells.

1 Dec 2011

Botulism toxins could be re-engineered for treating RA, asthma, psoriasis

The most poisonous substance on Earth - already used medically in small doses to treat certain nerve disorders and facial wrinkles - could be re-engineered for an expanded role in helping millions of people with rheumatoid arthritis, asthma, psoriasis and other diseases, scientists are reporting. Their study appears in ACS' journal Biochemistry.

1 Dec 2011

Compugen's Antibody Target Discovery Platform presented at 7th Annual European Antibody Congress

Speaking today at the plenary session of the 7th Annual European Antibody Congress in Geneva, Dr. Anat Cohen-Dayag, President and CEO of Compugen Ltd., presented Compugen's Antibody Target Discovery Platform, one of the Company's predictive discovery platforms for novel therapeutic targets.

1 Dec 2011

Fatal prion diseases have a hidden signature

Medical researchers in Canada and the United States recently published their joint findings that fatal prion diseases, which include BSE or "mad cow disease," have a hidden signature.

1 Dec 2011

Cancer researchers create catalog of possible targets for new treatments

As cancer researchers continue to identify genetic mutations driving different cancer subtypes, they are also creating a catalog of possible targets for new treatments.

1 Dec 2011

Researchers reveal ambivalent role of CXCL12/CXCR4 molecule in myocardial infarction

The chemokine CXCL12 acts as a chemical signal which mobilizes hematopoietic and other types of stem cells to leave the bone marrow and enter the circulation. Secretion of CXCL12 also guides these cells to sites at which the perfusion of tissue is sub-optimal due to localized obstruction of blood flow. These capabilities have made CXCL12 and its cognate receptor CXCR4 interesting candidates for therapies aimed at mitigating the effects of damage to the heart caused by myocardial infarction.

1 Dec 2011

Immune system stimulant used as suppressor to treat chronic graft-versus-host disease

In a study that seems to pivot on a paradox, scientists at Dana-Farber Cancer Institute have used an immune system stimulant as an immune system suppressor to treat a common, often debilitating side effect of donor stem cell transplantation in cancer patients. The effect, in some cases, was profound.

1 Dec 2011

Medical Science News

Established human embryonic cell lines vary from newly derived stem cell lines

Northwestern researchers receive NIAMSD grant to study scleroderma

New method reveals complete set of aberrant signaling pathways that give rise to cancers

Specific electromagnetic fields can block cancer cell growth

Mutation on surface of human red blood cells provides protection against vivax malaria

Agilent expands life sciences business with two strategic acquisitions

Researchers discover how distant satellite cells could help repair damaged muscles

Researchers identify cancer cell mitochondria as 'Achilles' heel' of tumor growth

Life as a couch potato can create new fat in fat cells

Body's surveillance for cancer causing damage and response to allergies share common pathway

Insights into causes of Idiopathic Pulmonary Fibrosis

Enrollment complete in Ceregene's CERE-120 Phase 2b trial for Parkinson's

Yale researchers monitor growth of laboratory-engineered blood vessels after implantation

Study presents high-resolution genome-wide p53-binding map for normal human cells

Botulism toxins could be re-engineered for treating RA, asthma, psoriasis

Compugen's Antibody Target Discovery Platform presented at 7th Annual European Antibody Congress

Fatal prion diseases have a hidden signature

Cancer researchers create catalog of possible targets for new treatments

Researchers reveal ambivalent role of CXCL12/CXCR4 molecule in myocardial infarction

Immune system stimulant used as suppressor to treat chronic graft-versus-host disease

Unlocking live single-cell functional insights

Fluidics in Modern Healthcare & Medical Device Innovation

How microRNA is transforming science: From discovery to diagnostics

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