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Research investigates MDR in human HCC

Hepatocellular carcinoma responds poorly to chemotherapy owing to MDR. Recent studies have shown the tumors derived from the colon, kidney, or adrenal cortex, and HCC exhibited overexpression of MDR1/P-gp. This overexpression results in a primary MDR phenotype of these cancers.

13 May 2010

Cognitive strategies lessen depression symptoms: Study

Moderate to severely depressed clients showed greater improvement in cognitive therapy when therapists emphasized changing how they think rather than how they behave, new research has found.

13 May 2010

Researchers to discuss various implications for personalized medicine during one-day symposium

On May 27, researchers with the National Human Genome Research Institute and the National Cancer Institute, along with Group Health Cooperative in Seattle and Henry Ford Health System, will debate and discuss that question during the one-day symposium "Multiplex Initiative: Implications for Personalized Medicine."

13 May 2010

Celera to present on AIDS pandemic, AZT drugs at Computational Molecular Biology Symposium

In 1985 there was little hope for people with AIDS. Newspapers and television screens were filled with ghastly pictures of emaciated figures dying from a disease that had no cure.

13 May 2010

RYGB surgery increases insulin activity in diabetes mellitus patients

Diabetes mellitus is a chronic metabolic disease resulted from, either decreased production of insulin or increased resistance to it from peripheral tissues or both factors combined together. While medical treatment remains the mainstay of treatment for diabetes, some surgical procedures, such as Roux-en-Y gastric bypass, have demonstrated some potential to be a treatment option for diabetes.

13 May 2010

Researchers develop new approach to immunotherapy of cancer

Harnessing the immune system is emerging as one of the most promising new ways to fight cancer. Most cancer cells are eliminated by the immune system; however, over a lifetime, a few may escape this immune surveillance and lead to tumors and metastases. Hence a formidable opportunity has been to find ways to make the immune system recognize the tumor as a foreign body and trigger a response.

13 May 2010

Music enhances new learning of information in AD patients

Researchers from Boston University School of Medicine (BUSM) have shown that patients with Alzheimer's disease (AD) are better able to remember new verbal information when it is provided in the context of music even when compared to healthy, older adults. The findings, which currently appear on-line in Neuropsychologia, offer possible applications in treating and caring for patients with AD.

13 May 2010

Four caged xanthones can inhibit growth of CCA cell lines: Research article

Cholangiocarcinoma is a malignant tumor, characterized by a poor prognosis and unresponsive to conventional chemotherapeutic agents. Therefore, searching for novel and effective therapeutic agents for CCA is necessary. In previous studies, several caged xanthones from G. hanburyi have been reported to be potent antiproliferatives as well as having anticancer and anti-tumor activities and they induce apoptosis in various cancer cell lines.

13 May 2010

Tobacco-free cigarettes may be more carcinogenic than tobacco products: Study

Using the same technique they developed to document the harmful effects of tobacco products, a team of researchers found that cigarettes made without tobacco or nicotine may be more carcinogenic because they actually induce more extensive DNA damage than tobacco products.

13 May 2010

NARSAD honours UNC's Patrick Sullivan with 2010 Distinguished Investigator Award

Patrick Sullivan, MD has received a 2010 Distinguished Investigator Award from NARSAD for a comparison of genetics in schizophrenia and bipolar disorder.

13 May 2010

Research sheds light on prenatal heart formation, chromosome 22q.11 deletion syndrome

Researchers studying the common genetic disorder chromosome 22q.11 deletion syndrome have identified key proteins that act together to regulate early embryonic development. One protein is essential to life; in animal studies, embryos without the protein do not survive past the first few days of gestation.

13 May 2010

Tripos releases SYBYL-X 1.1 molecular modeling suite

Tripos®, a leading provider of drug discovery informatics products and services, today announced the release and general availability of SYBYL-X Version 1.1. This new release focuses on enhancing research productivity for scientists in the pharmaceutical, agrochemical, flavors and fragrances, and related industries, featuring faster navigation, new menus and toolbars, and new ways to approach life science molecular discovery projects. Previous SYBYL versions have been the benchmark for the industry in molecular modeling, and customers using this new, next generation version have given it high marks.

13 May 2010

Regeneron Pharmaceuticals provides update on REGN727, REGN475 antibody product candidates

Regeneron Pharmaceuticals, Inc. (REGN) provided an update on two antibody product candidates in its pipeline and scheduled its first Investor Day to be held in New York City on July 15, 2010. Both product candidates, REGN727 (SAR236553) and, REGN475 (SAR164877) are being developed with sanofi-aventis under a global, strategic collaboration to discover, develop, and commercialize fully human antibodies.

13 May 2010

Tracking genes in infant's intestine helps compare early development of breast-fed and formula-fed babies

Is breast milk so different from infant formula? The ability to track which genes are operating in an infant's intestine has allowed University of Illinois scientists to compare the early development of breast-fed and formula-fed babies. They say the difference is very real.

13 May 2010

Microbiologists identify potential target in cattle to prevent E. coli strain

Microbiologists at UT Southwestern Medical Center, working with the Department of Agriculture, have identified a potential target in cattle that could be exploited to help prevent outbreaks of food-borne illnesses caused by a nasty strain of Escherichia coli.

13 May 2010

China Biologic subsidiary Shandong Taibang receives approval to build two new plasma stations

China Biologic Products, Inc., a leading plasma-based biopharmaceutical company in China, today announced that its majority-owned subsidiary, Shandong Taibang Biological Products Co. Ltd., has been approved by the Shandong Province Health Department to build two new plasma stations.

12 May 2010

FDA approves Aeterna Zentaris' AEZS-108 IND for bladder cancer

Aeterna Zentaris Inc., a late-stage drug development company specialized in oncology and endocrine therapy, today announced that the U.S. Food and Drug Administration (FDA) has approved the Company's Investigational New Drug (IND) application for its doxorubicin targeted conjugate compound, AEZS-108, in luteinizing hormone releasing hormone (LHRH) receptor positive urothelial (bladder) cancer.

12 May 2010

Genetic variations do not improve ability to predict risk of AD: Study

Although genome-wide analysis identified two genetic variations associated with Alzheimer disease, these variations did not improve the ability to predict the risk of AD, according to a study in the May 12 issue of JAMA.

12 May 2010

Marriage raises life expectancy

Marriage is more beneficial for men than for women - at least for those who want a long life. Previous studies have shown that men with younger wives live longer. While it had long been assumed that women with younger husbands also live longer, in a new study Sven Drefahl from the Max Planck Institute for Demographic Research (MPIDR) in Rostock, Germany, has shown that this is not the case. Instead, the greater the age difference from the husband, the lower the wife's life expectancy.

12 May 2010

Sanford-Burnham Scientific Symposium provides wealth of information on microRNAs, RNAi

Investigators from around the country came to Sanford-Burnham Medical Research Institute (Sanford-Burnham) on Friday, May 7, to share their knowledge of the burgeoning young field of microRNAs. These small non-coding nucleic acids turn off proteins and have been implicated in viral infection, cancer, cardiovascular disease, HIV and numerous other conditions.

12 May 2010

Medical Science News

Research investigates MDR in human HCC

Cognitive strategies lessen depression symptoms: Study

Researchers to discuss various implications for personalized medicine during one-day symposium

Celera to present on AIDS pandemic, AZT drugs at Computational Molecular Biology Symposium

RYGB surgery increases insulin activity in diabetes mellitus patients

Researchers develop new approach to immunotherapy of cancer

Music enhances new learning of information in AD patients

Four caged xanthones can inhibit growth of CCA cell lines: Research article

Tobacco-free cigarettes may be more carcinogenic than tobacco products: Study

NARSAD honours UNC's Patrick Sullivan with 2010 Distinguished Investigator Award

Research sheds light on prenatal heart formation, chromosome 22q.11 deletion syndrome

Tripos releases SYBYL-X 1.1 molecular modeling suite

Regeneron Pharmaceuticals provides update on REGN727, REGN475 antibody product candidates

Tracking genes in infant's intestine helps compare early development of breast-fed and formula-fed babies

Microbiologists identify potential target in cattle to prevent E. coli strain

China Biologic subsidiary Shandong Taibang receives approval to build two new plasma stations

FDA approves Aeterna Zentaris' AEZS-108 IND for bladder cancer

Genetic variations do not improve ability to predict risk of AD: Study

Marriage raises life expectancy

Sanford-Burnham Scientific Symposium provides wealth of information on microRNAs, RNAi

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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