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Cummings School granted U.S. Patent for antibody-based treatment against Hemolytic Uremic Syndrome

Researchers at the Cummings School of Veterinary Medicine have received U.S. patent approval for an antibody-based treatment for Hemolytic Uremic Syndrome (HUS), a potentially fatal outcome of E. coli poisoning and the leading cause of kidney failure in children.

1 Mar 2011

Chromosomally unstable bowel cancer cells more resistant to chemotherapy treatments, targeted drugs

Cancer Research UK scientists have made an important step towards developing personalised bowel cancer treatment by identifying which tumours are more likely to become drug resistant, according to research published in Cancer Research today.

1 Mar 2011

Gut bacteria could exert control over metabolic functions of other organs

Bacteria in the human gut may not just be helping digest food but also could be exerting some level of control over the metabolic functions of other organs, like the liver, according to research published this week in the online journal mBio-. These findings offer new understanding of the symbiotic relationship between humans and their gut microbes and how changes to the microbiota can impact overall health.

1 Mar 2011

Leptin receptor antagonist peptide demonstrates efficacy against triple negative breast cancer

A new peptide developed by researchers in Temple University's College of Science and Technology has demonstrated efficacy against triple negative breast cancer.

1 Mar 2011

New personalized therapy fools cancer cells into killing themselves

A Wayne State University School of Medicine physician-researcher has developed a personalized therapy to treat a wide range of cancers. The treatment is based on a naturally occurring human enzyme that has been genetically modified to fool cancer cells into killing themselves.

1 Mar 2011

'Tea and Toast Syndrome' leads to loss of wellness and muscle in seniors

Elderly people who live on their own that don't prepare whole meals or don't know how tend to dwindle their intake to "tea and toast" at the expense of vital nutrients and their health, according to an article published in the February issue of Food Nutrition & Science.

1 Mar 2011

Santaris licenses miR-33 from MGH to treat cardiovascular disorders

Santaris Pharma A/S, a clinical-stage biopharmaceutical company focused on the research and development of mRNA and microRNA targeted therapies, today announced that the Company has obtained an exclusive license from Massachusetts General Hospital for intellectual property related to the regulation of miR-33 for the treatment of cardiovascular disorders.

1 Mar 2011

Cellectis launches new TALEN Access tool for genome customization

Cellectis bioresearch, a specialist in genome customization and subsidiary of Cellectis, has today launched TALEN Access, the first fee-for-service custom TALEN.

1 Mar 2011

Aggressive treatment of T3 and T4 NSCLC with induction chemoradiotherapy may improve survival

Researchers from Boston University School of Medicine (BUSM) have found that patients with node negative T3 and T4 non-small lung cancer who underwent chemotherapy before surgery had more than three times the survival rate than patients who only underwent surgery. These findings currently appear on-line in the Journal of Thoracic and Cardiovascular Surgery.

1 Mar 2011

Brain's reward/motivation circuits linked to compulsive overeating

A brain imaging study at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory reveals a subtle difference between ordinary obese subjects and those who compulsively overeat, or binge: In binge eaters but not ordinary obese subjects, the mere sight or smell of favorite foods triggers a spike in dopamine - a brain chemical linked to reward and motivation.

1 Mar 2011

Dermatan sulfate holds potential as an additional biomarker for Sanfilippo disease

Sanfilippo disease is a rare disorder caused by the failure of enzymes to break down specific kinds of complex carbohydrates, resulting in their accumulation in cells and often severe physical and neurological problems - and sometimes early death.

1 Mar 2011

Renishaw launches first RUO multiplex assay system

Renishaw Diagnostics Ltd, a world leading provider of trace level detection technologies based on the exploitation of surface enhanced Raman scattering and surface enhanced resonance Raman scattering, for research and molecular diagnostics applications, today announced the launch of its first research use only multiplex assay system which allows precious research samples to be 'screened' for 10 or more 'targets', from a single sample.

1 Mar 2011

New process automatically ensures optimum tension for sutures in minimally invasive surgeries

More and more often, abdominal surgeries are being carried out in a minimally invasive manner. A small incision in the abdominal wall is sufficient for the surgeon to be able to insert the instrument and make the organs visible with an endoscope. This technique is gentler and does not stress the body as much as traditional surgeries do.

1 Mar 2011

Protein pathway may hold a clue for understanding Parkinson's disease

A protein pathway that may hold the secret to understanding Parkinson's disease has been discovered and explained by Iowa State University researchers.

1 Mar 2011

Researcher identifies substance that inhibits cancer growth by activating 'dark genome'

A research study coordinated by Manel Esteller, researcher at Bellvitge Biomedical Research Institute (IDIBELL) has identified a substance that inhibits cancer growth by activating the so‑called "dark genome" (or non‑coding DNA) and micro‑RNA molecules. The study appears this week in the journal Proceedings of the National Academy of Sciences (PNAS).

1 Mar 2011

Study: Visual cortex can dramatically change its function

When your brain encounters sensory stimuli, such as the scent of your morning coffee or the sound of a honking car, that input gets shuttled to the appropriate brain region for analysis. The coffee aroma goes to the olfactory cortex, while sounds are processed in the auditory cortex.

1 Mar 2011

Cancer drug may help combat flu

Ever get a flu shot and still get the flu? If so, there's new hope for flu-free winters in the years to come thanks to a new discovery by researchers who found that a drug called DMXAA, originally developed as anti-tumor agent, enhances the ability of flu vaccines to ward off this deadly virus.

1 Mar 2011

Research uncovers new details about protein interactions in retina

Science fiction novelist and scholar Issac Asimov once said, "The most exciting phrase to hear in science, the one that heralds new discoveries, is not 'Eureka!' but 'That's funny.' " This recently rang true for an international team of researchers when they observed something they did not expect.

1 Mar 2011

Nile plans to develop novel therapeutics for ADHF

Nile Therapeutics, Inc., a biopharmaceutical company focused on the development of novel therapeutics for cardiovascular disease, announced plans to pursue a new indication in the field of heart failure.

1 Mar 2011

Two genes linked to binge drinking

University of Maryland School of Medicine researchers have identified two genes associated with binge drinking that may open doors to new, more effective treatments for excessive alcohol drinking. The scientists found that manipulating two receptors in the brain, GABA receptors and toll-like receptor 4 (TLR4), "caused profound reduction" of binge drinking for two weeks in rodents that had been bred and trained to drink excessively. The study was published online the week of Feb. 28 in the journal the Proceedings of the National Academy of Sciences.

1 Mar 2011

Medical Science News

Cummings School granted U.S. Patent for antibody-based treatment against Hemolytic Uremic Syndrome

Chromosomally unstable bowel cancer cells more resistant to chemotherapy treatments, targeted drugs

Gut bacteria could exert control over metabolic functions of other organs

Leptin receptor antagonist peptide demonstrates efficacy against triple negative breast cancer

New personalized therapy fools cancer cells into killing themselves

'Tea and Toast Syndrome' leads to loss of wellness and muscle in seniors

Santaris licenses miR-33 from MGH to treat cardiovascular disorders

Cellectis launches new TALEN Access tool for genome customization

Aggressive treatment of T3 and T4 NSCLC with induction chemoradiotherapy may improve survival

Brain's reward/motivation circuits linked to compulsive overeating

Dermatan sulfate holds potential as an additional biomarker for Sanfilippo disease

Renishaw launches first RUO multiplex assay system

New process automatically ensures optimum tension for sutures in minimally invasive surgeries

Protein pathway may hold a clue for understanding Parkinson's disease

Researcher identifies substance that inhibits cancer growth by activating 'dark genome'

Study: Visual cortex can dramatically change its function

Cancer drug may help combat flu

Research uncovers new details about protein interactions in retina

Nile plans to develop novel therapeutics for ADHF

Two genes linked to binge drinking

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