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DFG to form new collaborative research centers as of 1 July 2011

The Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) will establish 21 new Collaborative Research Centres (CRCs) as of 1 July 2011. This was decided by the relevant Grants Committee at its spring meeting in Bonn.

4 Jun 2011

Study links loss of PTEN gene with patient's response to melanoma therapy

Genetic analysis of the tumors from patients with advanced melanoma can clue researchers in to how well patients will respond to a therapy that targets the growth-promoting protein called BRAF, a researcher from the Perelman School of Medicine at the University of Pennsylvania will report on Monday, June 6 at the annual meeting of the American Society of Clinical Oncology.

4 Jun 2011

Scientists find way to protect kidney from cancer drug toxicity

Scientists may have a way to make the powerful cancer drug cisplatin less toxic to the kidneys and more effective against some cancers.

4 Jun 2011

Preliminary data from Ion PGM sequencer reveals German E. coli outbreak is a new hybrid strain

Life Technologies Corporation today announced that preliminary data from DNA sequencing performed in cooperation with the University Hospital Muenster, Germany, on the Ion Personal Genome Machine strongly suggests that the bacterium at the root of the deadly outbreak in Germany is a new hybrid type of pathogenic E. coli strains.

4 Jun 2011

Starving breast cancer cells of hedgehog significantly slows tumour growth and spread

While it is already known that breast cancer cells create the conditions for their own survival by communicating their needs to the healthy cells that surround them, Australian researchers have identified a new way of turning off that cellular cross talk.

4 Jun 2011

GW researchers demonstrate Mta1 gene's role in survival of schistosomes

By using mice lacking a crucial gene that controls the process of chromatin remodeling of cytokines including those responsible for inflammation and comparing them to normal wild type mice with the gene, researchers at the George Washington University School of Medicine and Health Sciences have shown that the gene, Mta1, is essential for the parasite Schistosoma haematobium to establish a productive infection and survival in the host.

4 Jun 2011

Researchers develop new technology to detect neurological symptoms associated with epileptic seizure

Tiny electrodes have been coated with a drug-loaded polymer in an attempt to design an implant capable of detecting a number of neurological symptoms, such as those associated with an epileptic seizure, and treating them simultaneously.

4 Jun 2011

Dendritic cells secrete signal molecule that contributes to pathogenesis of atherosclerosis

Atherosclerosis is the most common cause of cardiovascular disease, and results from chronic inflammation of arterial vessel walls. An international collaboration led by Professor Christian Weber of Ludwig-Maximilians-Universität (LMU) in Munich and Privatdozentin Alma Zernecke of Würzburg University now shows that dendritic cells stimulate this process by derailing a mechanism that normally acts as a brake on immune reactions.

4 Jun 2011

BGI genome sequencing identifies new super-toxic bacteria as cause of current European epidemic

The recent outbreak of an E. coli infection in Germany has resulted in serious concerns about the potential appearance of a new deadly strain of bacteria.

4 Jun 2011

Brown University researchers develop 2-D maps of neural circuitry in human brain

Medical imaging systems allow neurologists to summon 3-D color renditions of the brain at a moment's notice, yielding valuable insights. But sometimes there can be too much detail; important elements can go unnoticed.

4 Jun 2011

Researchers identify 'epigenetic fingerprints' of healthy volunteers, patients with common diseases

Until a decade, it was believed that differences between people were due solely to the existence of genetic changes, which are alterations in the sequence of our genes. The discoveries made during these last ten years show that beings with the same genetics like the twins and cloned animals may have different characteristics and disease due to epigenetic changes.

4 Jun 2011

MreB protein molecules assemble into larger units in bacterial cell wall

Almost all bacteria owe their structure to an outer cell wall that interacts closely with the supporting MreB protein inside the cell. As scientists at the Max Planck Institute for Biochemistry and at the French INRA now show, MreB molecules assemble into larger units, but not - as previously believed - into continuous helical structures.

4 Jun 2011

Nano-formulated indomethacin at lower dose effective in treating pain

A novel, lower-dose formulation of indomethacin, a widely used pain reliever, is absorbed faster by the body than a standard formulation and maintains comparable maximum concentrations in the blood despite being administered at a lower dose, according to a study to be reported here tomorrow at the annual meeting of the American Headache Society.

4 Jun 2011

Enzyme Research journal publishes new peer-reviewed article involving Protandim

LifeVantage Corporation, the maker of Protandim, a clinically demonstrated, science-based therapy for the reduction of oxidative stress by the synergistic activation of Nrf2, announced today that a new peer-reviewed review article involving Protandim was published in the scientific journal Enzyme Research.

4 Jun 2011

Johns Hopkins researchers solve long-standing mystery of Warburg effect

It's long been known that cancer cells eat a lot of sugar to stay alive. In fact, where normal, noncancerous cells generate energy from using some sugar and a lot of oxygen, cancerous cells use virtually no oxygen and a lot of sugar.

4 Jun 2011

PTEN does not reduce effectiveness of breast cancer drug, Herceptin: Study

Contrary to what many oncologists had thought, a tumor suppressor protein known as PTEN does not reduce the effectiveness of the breast cancer drug Herceptin, according to a study by Mayo Clinic and North Central Cancer Research Group investigators.

4 Jun 2011

Scientists demonstrate why B cells exposed to chronic HIV shut down, how they can be reactivated

Scientists at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, have demonstrated why certain immune cells chronically exposed to HIV shut down, and how they can be reactivated.

4 Jun 2011

New discoveries about role of blood vessels in early lung development

A research team at The Saban Research Institute of Children's Hospital Los Angeles has made critical new discoveries about the role of blood vessels in guiding early lung development, especially in the essential, highly reproducible branching pattern of lung airways.

4 Jun 2011

Insight into understanding of normal muscle growth

Revealing another part of the story of muscle development, Johns Hopkins researchers have shown how the cytoskeleton from one muscle cell builds finger-like projections that invade into another muscle cell's territory, eventually forcing the cells to combine.

4 Jun 2011

Decreasing iron-storing protein expression can enhance action of brain cancer therapy: Researchers

Brain cancer therapy may be more effective if the expression of an iron-storing protein is decreased to enhance the action of therapeutic drugs on brain cancer cells, according to Penn State College of Medicine researchers.

4 Jun 2011

Medical Science News

DFG to form new collaborative research centers as of 1 July 2011

Study links loss of PTEN gene with patient's response to melanoma therapy

Scientists find way to protect kidney from cancer drug toxicity

Preliminary data from Ion PGM sequencer reveals German E. coli outbreak is a new hybrid strain

Starving breast cancer cells of hedgehog significantly slows tumour growth and spread

GW researchers demonstrate Mta1 gene's role in survival of schistosomes

Researchers develop new technology to detect neurological symptoms associated with epileptic seizure

Dendritic cells secrete signal molecule that contributes to pathogenesis of atherosclerosis

BGI genome sequencing identifies new super-toxic bacteria as cause of current European epidemic

Brown University researchers develop 2-D maps of neural circuitry in human brain

Researchers identify 'epigenetic fingerprints' of healthy volunteers, patients with common diseases

MreB protein molecules assemble into larger units in bacterial cell wall

Nano-formulated indomethacin at lower dose effective in treating pain

Enzyme Research journal publishes new peer-reviewed article involving Protandim

Johns Hopkins researchers solve long-standing mystery of Warburg effect

PTEN does not reduce effectiveness of breast cancer drug, Herceptin: Study

Scientists demonstrate why B cells exposed to chronic HIV shut down, how they can be reactivated

New discoveries about role of blood vessels in early lung development

Insight into understanding of normal muscle growth

Decreasing iron-storing protein expression can enhance action of brain cancer therapy: Researchers

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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