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Researchers discover 'common set of dysregulated miRNAs in murine lupus models'

Potentially impacting future diagnosis and treatment of lupus, an immune illness affecting more than 5 million people worldwide, researchers at the Virginia-Maryland Regional College of Veterinary Medicine at Virginia Tech have likely uncovered where the breakdown in the body's lymphocyte molecular regulatory machinery is occurring.

1 Feb 2011

FDA approves 'Cornell Dots' for first clinical trial in humans to diagnose cancer

"Cornell Dots" - brightly glowing nanoparticles - may soon be used to light up cancer cells to aid in diagnosing and treating cancer. The U.S. Food and Drug Administration has approved the first clinical trial in humans of the new technology.

1 Feb 2011

Novel personalized therapy could treat metastatic melanoma and metastatic synovial cell sarcoma

Researchers have found that a novel form of personalized therapy that genetically engineers a patient's own anti-tumor immune cells to fight tumors could treat metastatic melanoma and metastatic synovial cell sarcoma, representing a potentially new therapeutic approach against these and other cancers.

1 Feb 2011

Global consortium aims to discover and map all Alzheimer's genes

The launch of the International Genomics of Alzheimer's Project (IGAP) – a collaboration formed to discover and map the genes that contribute to Alzheimer's disease – was announced today by a multi-national group of researchers. The collaborative effort, spanning universities from both Europe and the United States, will combine the knowledge, staff and resources of four consortia that conduct research on Alzheimer's disease genetics.

1 Feb 2011

Avantra Biosciences selects TGen Drug Development for new biomarker quantitation platform

Avantra Biosciences today announced the selection of TGen Drug Development as a key test site for Avantra's new biomarker quantitation platform.

1 Feb 2011

Yale University scientists synthesize lomaiviticin that appears to destroy cancer stem cells

A team of Yale University scientists has synthesized for the first time a chemical compound called lomaiviticin aglycon, leading to the development of a new class of molecules that appear to target and destroy cancer stem cells.

1 Feb 2011

Free radicals may damage eyes of patients with Fuchs Endothelial Corneal Dystrophy

Scientists have found that free radicals (unstable molecules that cause the death of cells as the body ages) may also cause the damage in the eyes of patients with Fuchs Endothelial Corneal Dystrophy (FECD), a hereditary disease that is one of the most common reasons for corneal transplants worldwide.

1 Feb 2011

Scientists devise safer way to create iPS cells

Researchers at Johns Hopkins have found a better way to create induced pluripotent stem (iPS) cells-adult cells reprogrammed with the properties of embryonic stem cells-from a small blood sample. This new method, described last week in Cell Research, avoids creating DNA changes that could lead to tumor formation.

1 Feb 2011

Research on triple negative disease can benefit patients with breat cancer

Research to develop more effective treatments for triple negative breast cancer -- a difficult disease to cure -- could someday benefit all breast cancer patients, reports Dr. Frederick C. Tucker, Jr. of Fredericksburg Oncology.

1 Feb 2011

DNA Direct implements four new health plan clients for molecular diagnostic and genetic tests

DNA Direct, a wholly owned subsidiary of Medco Health Solutions, Inc. and a provider of guidance and decision support for genomic medicine, today announced four new health plan clients that are implementing DNA Direct's Policy & Benefit Support Program for molecular diagnostic and genetic tests.

1 Feb 2011

Simple hTERT analysis may provide useful prognostic tool in advanced non-small cell lung cancer

High levels of circulating DNA may indicate faster progression of lung cancer and lower overall survival, according to a study published in the February edition of the Journal of Thoracic Oncology, the official publication of the International Association for the Study of Lung Cancer (IASLC).

1 Feb 2011

Silicon dioxide coated rust nanoparticles to fight cervical cancer

The next big thing in medical diagnostics could be minutes particles of rust, iron oxide, coated with the material from which sand is formed, silicon dioxide. These magnetic nanoparticles, a mere 29 to 230 nanometers across, can be used to trap antibodies to the virus that causes cervical cancer and to the bacteria that causes potentially lethal diarrhea.

1 Feb 2011

Study finds E2F5 transcription factor commonly overexpressed in primary human HCC

E2F5 is a member of the E2F transcription factor family, and plays a key role in cell growth and proliferation. Overexpression of E2F5 has been reported in various human cancers, but not in liver cancer, and its biological implication is largely unknown. It is not known whether E2F5 plays a tumor suppressor role or an oncogenic role.

1 Feb 2011

IASLC publishes new international multidisciplinary classification for lung adenocarcinoma

Three of the world's top lung associations have published a new international multidisciplinary classification of lung adenocarcinoma, the first revision to the classification in six years.

1 Feb 2011

Scientists create 'reporter mouse' to close gap between kidney injury and diagnosis

The current check for kidney disease is a simple blood test for serum creatinine, but it can take longer than two days for this metabolite to accumulate to levels that are significant enough to indicate kidney damage - and by then it may be too late to intervene.

1 Feb 2011

Eurogentec, ImaginAb announce collaboration to produce engineered antibody fragments

ImaginAb, and Eurogentec S.A. announce a development collaboration to establish a novel system for producing engineered antibody fragments. The two companies will produce ImaginAb's optimized antibody fragments with Eurogentec's high-performance Pichia pastoris expression system.

1 Feb 2011

Scientist identifies natural signaling molecule that can prevent Hemophilia A

A scientist from The Scripps Research Institute has identified a new role for a natural signaling molecule in preventing blood clot formation. The molecule could become a target for the development of novel and cost-effective treatments for blood clotting diseases such as Hemophilia A.

1 Feb 2011

New research finding shows strong relationship between gut bacteria and fatty liver

The more we learn about biology, the closer we get to being able to treat disease - and the more complicated our understanding of disease itself becomes. A new research finding showing a strong relationship between complex microbial ecologies in human intestines and the common but serious medical condition known as fatty liver illustrates this paradox.

1 Feb 2011

Researchers study peripheral blood Tregs as disease marker of gastric cancer

T-regulatory lymphocytes are a subset of T lymphocytes that are involved in the mechanism of immunotolerance to self- and allo-antigens. Activity of these cells is one of the mechanisms of immune evasion of tumors, which inhibits the antitumor activity of effector cells.

1 Feb 2011

Histamine can be an important molecule to develop new treatments for MS

If you think histamines are your nemesis during allergy season, here's something that might change your perspective. New research published in the Journal of Leukocyte Biology shows that histamine could be an important molecule to developing new treatments for multiple sclerosis.

1 Feb 2011

Medical Science News

Researchers discover 'common set of dysregulated miRNAs in murine lupus models'

FDA approves 'Cornell Dots' for first clinical trial in humans to diagnose cancer

Novel personalized therapy could treat metastatic melanoma and metastatic synovial cell sarcoma

Global consortium aims to discover and map all Alzheimer's genes

Avantra Biosciences selects TGen Drug Development for new biomarker quantitation platform

Yale University scientists synthesize lomaiviticin that appears to destroy cancer stem cells

Free radicals may damage eyes of patients with Fuchs Endothelial Corneal Dystrophy

Scientists devise safer way to create iPS cells

Research on triple negative disease can benefit patients with breat cancer

DNA Direct implements four new health plan clients for molecular diagnostic and genetic tests

Simple hTERT analysis may provide useful prognostic tool in advanced non-small cell lung cancer

Silicon dioxide coated rust nanoparticles to fight cervical cancer

Study finds E2F5 transcription factor commonly overexpressed in primary human HCC

IASLC publishes new international multidisciplinary classification for lung adenocarcinoma

Scientists create 'reporter mouse' to close gap between kidney injury and diagnosis

Eurogentec, ImaginAb announce collaboration to produce engineered antibody fragments

Scientist identifies natural signaling molecule that can prevent Hemophilia A

New research finding shows strong relationship between gut bacteria and fatty liver

Researchers study peripheral blood Tregs as disease marker of gastric cancer

Histamine can be an important molecule to develop new treatments for MS

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CellVoyant's AI-Powered Vision for the Future of Cell Therapy

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