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Dr Russell Wallis, Reader and RCUK Academic Fellow to give Frank May Prize Lecture 2010

The Frank May Prize Lecture 2010, entitled 'Fishing for Complement: innate targeting of microbial pathogens', will be given by Dr Russell Wallis, Reader and RCUK Academic Fellow in the Department of Infection, Immunity and Inflammation, and Department of Biochemistry.

5 Mar 2011

iPrEx update, bone mineral density study highlighted at day three of 18th CROI

The 18th Conference on Retroviruses and Opportunistic Infections is being held at the Hynes Convention Center in Boston from February 27 through March 2. Day three of this major HIV/AIDS research conference included the following selected presentations from scientists supported by the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health.

5 Mar 2011

CDI announces publication of footprint-free iPSCs production method in PLoS ONE journal

Cellular Dynamics International, the world's largest producer of human tissue cells for drug discovery and safety testing, today announced the publication of research demonstrating an efficient and scalable method of creating DNA integration-free, or footprint-free, induced pluripotent stem cells under a feeder-free condition using chemically defined media.

5 Mar 2011

Denture wearers advised to pay special attention to consumption of zinc

From its involvement in a healthy immune system to its role in cell growth, zinc is an essential mineral for the human body. Zinc deficiency is a worldwide problem that affects approximately 4 million people in the U.S. alone.

5 Mar 2011

Caris Life Sciences to highlight new approaches for gynecologic cancers at SGO 2011 conference

Caris Life Sciences, Inc., a leading biosciences company focused on enabling precise and personalized healthcare through the highest quality anatomic pathology, molecular profiling, and blood-based diagnostic services, today announced highlights from the company's upcoming symposium, "Using Biomarker Expression to Guide Therapy: An Evidence-Based Approach for Gynecologic Cancers," at the Society of Gynecologic Oncologists 2011 Annual Meeting on Women's Cancer in Orlando, FL on March 6.

5 Mar 2011

Bessel beam plane illumination microscopy reveals 3-D structures of living cells

A new microscope invented by scientists at Howard Hughes Medical Institute's Janelia Farm Research Campus will let researchers use an exquisitely thin sheet of light -- similar to that used in supermarket bar-code scanners -- to peer inside single living cells, revealing the three-dimensional shapes of cellular landmarks in unprecedented detail.

5 Mar 2011

Novel gene therapy can promote removal of amyloid plaques and prevent Alzheimer's disease

Gene therapy that boosts the ability of brain cells to gobble up toxic proteins prevents development of Alzheimer's disease in mice that are predestined to develop it, report researchers at Georgetown University Medical Center. They say the treatment - which is given just once - could potentially do the same in people at the beginning stages of the disease.

5 Mar 2011

Scientists detail role of TDP-43 in ALS pathology

Amyotrophic lateral sclerosis, known as ALS or more popularly, Lou Gehrig's disease, is a notorious neurodegenerative condition characterized by the progressive deterioration of brain and spinal cord neurons, resulting in the gradual but catastrophic loss of muscle control and ultimately, death.

5 Mar 2011

Article outlines role of transcriptional mutagenesis in tumor development

DNA provides the instruction manual for all life forms. Occasionally, instructions are not carried out properly, and bad messages are sent leading to the creation of mutant proteins and possible tumor development.

5 Mar 2011

Study: Overweight adolescents may have high risk of less bone mass

Overweight adolescents already struggling with risk factors such as insulin resistance may need to add weak bones to their list of health concerns, researchers report.

5 Mar 2011

Study: BMP can improve dental implant success

Using a bone-creating protein to augment the maxillary sinus could improve dental implant success, according to Georgia Health Sciences University researchers.

5 Mar 2011

Brain enzyme can restore even old, fading memories, say researchers

Even long after it is formed, a memory in rats can be enhanced or erased by increasing or decreasing the activity of a brain enzyme, say researchers supported, in part, by the National Institutes of Health.

4 Mar 2011

Scientist discovers new mechanism for regulation of gene expression

Dr. David Levin, Professor of Molecular & Cell Biology at Boston University Henry M. Goldman School of Dental Medicine and Professor of Microbiology at Boston University School of Medicine discovered recently a novel, evolutionarily conserved mechanism for the regulation of gene expression.

4 Mar 2011

Sangamo's preclinical ZFN-gene modification studies for HIV/AIDS treatment presented at CROI

Sangamo BioSciences, Inc. announced that data from its programs to develop ZFN-based therapeutic approaches for the treatment of HIV/AIDS were discussed in four oral presentations at the 18th Conference on Retroviruses and Opportunistic Infections, held in Boston from February 27 to March 2, 2011.

4 Mar 2011

Researchers transform human embryonic stem cell into neuron that dies early in Alzheimer's disease

Northwestern Medicine researchers for the first time have transformed a human embryonic stem cell into a critical type of neuron that dies early in Alzheimer's disease and is a major cause of memory loss.

4 Mar 2011

New promising detection technology identifies cancer cells early

Yesterday's Wall Street Journal (March 1) published a lead article on page D1 entitled "Researchers Create Better Ways To Spot Cancer Cells", which described the research by Dr. Edward R. Flynn, of Senior Scientific LLC. The article was authored by Shirley S. Wang.

4 Mar 2011

Apple polyphenols prolong average lifespan of fruit flies

Scientists are reporting the first evidence that consumption of a healthful antioxidant substance in apples extends the average lifespan of test animals, and does so by 10 percent. The new results, obtained with fruit flies - stand-ins for humans in hundreds of research projects each year - bolster similar findings on apple antioxidants in other animal tests. The study appears in ACS's Journal of Agricultural and Food Chemistry.

4 Mar 2011

SERS nanosubstrates revolutionize medical diagnostics

Gold-coated substrates of gallium nitride with specifically formed surface, developed by researchers from the Institute of Physical Chemistry of the Polish Academy of Sciences and the Institute of High Pressure Physics of the PAS display worldwide unique properties. Thanks to these new substrates, an extremely sensitive SERS analytical technique, capable of detecting even single molecules, after decades of waiting in specialized laboratories has finally got a chance to widespread and revolutionize medical diagnostics.

4 Mar 2011

New study finds liver instead of the brain as source of Alzheimer’s plaques

Unexpected results from a Scripps Research Institute and ModGene, LLC study could completely alter scientists' ideas about Alzheimer's disease—pointing to the liver instead of the brain as the source of the "amyloid" that deposits as brain plaques associated with this devastating condition. The findings could offer a relatively simple approach for Alzheimer's prevention and treatment.

4 Mar 2011

Triptolide isolated from Chinese medicinal plant blocks gene control machinery in cells

Researchers at the Johns Hopkins School of Medicine have discovered that a natural product isolated from a traditional Chinese medicinal plant commonly known as thunder god vine, or lei gong teng, and used for hundreds of years to treat many conditions including rheumatoid arthritis works by blocking gene control machinery in the cell. The report, published as a cover story of the March issue of Nature Chemical Biology, suggests that the natural product could be a starting point for developing new anticancer drugs.

4 Mar 2011

Medical Science News

Dr Russell Wallis, Reader and RCUK Academic Fellow to give Frank May Prize Lecture 2010

iPrEx update, bone mineral density study highlighted at day three of 18th CROI

CDI announces publication of footprint-free iPSCs production method in PLoS ONE journal

Denture wearers advised to pay special attention to consumption of zinc

Caris Life Sciences to highlight new approaches for gynecologic cancers at SGO 2011 conference

Bessel beam plane illumination microscopy reveals 3-D structures of living cells

Novel gene therapy can promote removal of amyloid plaques and prevent Alzheimer's disease

Scientists detail role of TDP-43 in ALS pathology

Article outlines role of transcriptional mutagenesis in tumor development

Study: Overweight adolescents may have high risk of less bone mass

Study: BMP can improve dental implant success

Brain enzyme can restore even old, fading memories, say researchers

Scientist discovers new mechanism for regulation of gene expression

Sangamo's preclinical ZFN-gene modification studies for HIV/AIDS treatment presented at CROI

Researchers transform human embryonic stem cell into neuron that dies early in Alzheimer's disease

New promising detection technology identifies cancer cells early

Apple polyphenols prolong average lifespan of fruit flies

SERS nanosubstrates revolutionize medical diagnostics

New study finds liver instead of the brain as source of Alzheimer’s plaques

Triptolide isolated from Chinese medicinal plant blocks gene control machinery in cells

Synthetic Biology and the Pursuit of Living Diagnostics

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

Evolving spectrophotometry for modern biopharma workflows

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