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Understanding how natural genetic variation contributes to adaptive responses to low oxygen

Humans are still evolving, and Tatum Simonson, PhD, founder and co-director of the Center for Physiological Genomics of Low Oxygen at University of California School of Medicine, plans to use evolution to improve healthcare for all.

12 Feb 2024

Androgen receptor signaling found to upregulate gene driving melanoma severity in men

Method by which androgen-activated androgen receptors (ARs) increase fucosyltransferase 4 (FUT4) expression.

12 Feb 2024

Pregnant women show significant immune system changes linked to gut microbiome

How gut microbiota and metabolite changes relate to immune function during pregnancy.

12 Feb 2024

Genetics of estrogen production linked to endometrial cancer risk in postmenopausal women

A study in eBioMedicine identifies genetic factors regulating blood estrone levels in postmenopausal women, linking specific genetic loci to an increased risk of endometrial cancer, highlighting the role of non-ovarian estrogen production in cancer development.

11 Feb 2024

Prenatal exposure to phthalates linked to higher risk of preterm birth and low birth weight

Research in The Lancet Planetary Health links prenatal phthalate exposure to increased risks of preterm birth and low birth weight, underscoring the need for regulatory oversight on chemicals used in consumer products.

11 Feb 2024

New study finds 4’-fluorouridine effective against avian influenza in vitro and in vivo

A PLOS Pathogens study reveals 4’-fluorouridine effectively combats avian influenza in vitro and in animal models, showing promise as a treatment that overcomes resistance and reduces disease severity without significant adverse effects.

11 Feb 2024

Unlocking Alzheimer's secrets: Study pinpoints APOE4's harmful effect on lipids

UNC School of Medicine researcher Sarah Cohen, PhD, and Ian Windham, a former PhD student from the Cohen lab, have made a new discovery about apolipoprotein E (APOE) – the biggest genetic risk factor for late-onset Alzheimer's disease.

9 Feb 2024

Blood biomarkers in TGF-β pathway identify hidden liver cancer risk

A new research paper was published in Genes & Cancer on February 5, 2023, entitled, "Mechanistically based blood proteomic markers in the TGF-β pathway stratify risk of hepatocellular cancer in patients with cirrhosis."

9 Feb 2024

Immune system in the blood of Alzheimer's patients found to be epigenetically altered

A new Northwestern Medicine study has found the immune system in the blood of Alzheimer's patients is epigenetically altered.

9 Feb 2024

Small ultrasound sticker can monitor the stiffness of internal organs

MIT engineers have developed a small ultrasound sticker that can monitor the stiffness of organs deep inside the body.

9 Feb 2024

Scientists develop safer CAR T-cell strategy for treating lymphomas

In the treatment of aggressive lymphomas and blood cancer (leukaemia), so-called chimeric antigen receptor T cells (CAR T cells) are increasingly being used.

9 Feb 2024

Amputees regain temperature sensation with new prosthetic technology

Sensory feedback is important for amputees to be able to explore and interact with their environment. Now, researchers have developed a device that allows amputees to sense and respond to temperature by delivering thermal information from the prosthesis' fingertip to the amputee's residual limb.

9 Feb 2024

Large Language Models promise to revolutionize neuroscience research

The past year has seen major advances in Large Language Models (LLMs) such as ChatGPT. The ability of these models to interpret and produce human text sources (and other sequence data) has implications for people in many areas of human activity.

9 Feb 2024

Rucaparib and its major metabolite exhibit differential biological activity and synergy

Once they enter the body, drugs, apart from carrying out their therapeutic function, are biochemically transformed by the action of the metabolic machinery, a process that facilitates their expulsion.

9 Feb 2024

Children's Colorado announces its acceptance into the Pediatric Heart Network

Children's Hospital Colorado (Children's Colorado) is announcing its recent acceptance into the Pediatric Heart Network (PHN), a collective of leading hospitals working to improve outcomes and quality of life for children – and more recently adults – with heart disease.

9 Feb 2024

Medical Science News

Understanding how natural genetic variation contributes to adaptive responses to low oxygen

Androgen receptor signaling found to upregulate gene driving melanoma severity in men

Pregnant women show significant immune system changes linked to gut microbiome

Genetics of estrogen production linked to endometrial cancer risk in postmenopausal women

Prenatal exposure to phthalates linked to higher risk of preterm birth and low birth weight

New study finds 4’-fluorouridine effective against avian influenza in vitro and in vivo

Unlocking Alzheimer's secrets: Study pinpoints APOE4's harmful effect on lipids

Blood biomarkers in TGF-β pathway identify hidden liver cancer risk

Immune system in the blood of Alzheimer's patients found to be epigenetically altered

Small ultrasound sticker can monitor the stiffness of internal organs

Scientists develop safer CAR T-cell strategy for treating lymphomas

Amputees regain temperature sensation with new prosthetic technology

Large Language Models promise to revolutionize neuroscience research

Rucaparib and its major metabolite exhibit differential biological activity and synergy

Children's Colorado announces its acceptance into the Pediatric Heart Network

LSHTM researchers receive £2m funding to develop novel vaccines, diagnostics and therapeutics

Study provides an important advancement of knowledge by showing neural compensation in healthy aging brains

Study finds gender disparity in quality of life for individuals with food allergies

Women experience larger increase in antidepressant use after break-up than men, study suggests

Stapokibart shows promise in reducing nasal congestion in seasonal allergy patients, study finds

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?

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