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Histone H1 phosphorylation involved in control of ribosomal RNA gene transcription

A protein that helps pack DNA into the cell nucleus has an important role in regulating gene activity, scientists report. The researchers found that the protein, histone H1, also takes part in the formation of ribosomes, the cellular workbenches on which all proteins are made.

2 Jul 2010

Children's Hospital Boston researchers reprogram adult blood cells into iPS cells

In findings likely to make it easier and faster for stem cell biologists to generate patient-specific embryonic-like stem cells, researchers at Children's Hospital Boston have reprogrammed adult blood cells into induced pluripotent stem (iPS) cells.

2 Jul 2010

Compugen's CGEN-15001 recombinant fusion protein abolishes spontaneous relapses in animal model of MS

Compugen Ltd. announced today that administration of CGEN-15001 in an animal model of multiple sclerosis (MS) has been shown to completely abolish spontaneous relapses. In addition, administration of this novel molecule prior to disease onset demonstrated a pronounced delay of disease onset and a significant decrease in disease symptoms.

2 Jul 2010

Aushon BioSystems introduces new Human multiplex biomarker panels

Aushon BioSystems, Inc., a leading provider of advanced microarray instrumentation and laboratory services for biomarker discovery, development and analysis, has launched new Human multiplex biomarker panels for the quantification of eight biomarkers related to drug-induced kidney damage, or nephrotoxicity.

2 Jul 2010

Plant extract effective against ulcerative colitis in mice

A South Dakota State University scientist's research shows an extract made from a food plant in the Brassica family was effective in alleviating signs of ulcerative colitis, an inflammatory bowel condition, in mice.

2 Jul 2010

Novel imaging agents and techniques can revolutionize medical imaging science: JNM

A study published in the July issue of The Journal of Nuclear Medicine (JNM) reports on investigative research of a novel optical imaging technique called "Cerenkov luminescence imaging (CLI)." According to the authors, the technique could lead to the faster and more cost-effective development of radiopharmaceuticals for the diagnosis and treatment of cancer and other conditions.

2 Jul 2010

Frozen blood samples shows promise to study mechanism of blood disorders

Cells from frozen human blood samples can be reprogrammed to an embryonic-stem-cell-like state, according to Whitehead Institute researchers. These cells can be multiplied and used to study the genetic and molecular mechanisms of blood disorders and other diseases.

2 Jul 2010

FUISZ files new patent, receives notice of issuance for patent claims for blood analysis devices

First, FUISZ announced that it has received a notice of issuance from the United States Patent and Trademark Office for patent claims that cover a direct connection between prescribing physicians and blood analysis devices.

2 Jul 2010

DNA damage caused by UVA radiation leads to melanoma

A new study by researchers at NYU School of Medicine found that UVA radiation damages the DNA in human melanocyte cells, causing mutations that can lead to melanoma. Melanocytes, which contain a substance called melanin that darkens the skin to protect it from the ultraviolet rays of the sun, are more vulnerable to UVA radiation than normal skin cells because they are unable to repair themselves as efficiently.

2 Jul 2010

Amedica, SUNY Upstate Medical University partner in comparative study of biomaterials

Amedica Corporation, a spinal and orthopaedic implant and instrument manufacturer focused on unique silicon nitride (SiN) ceramic technologies, announced that it has entered into an agreement with SUNY Upstate Medical University to conduct an additional research study that evaluates the company's SiN ceramic technology compared to PEEK interbody fusion devices. The two-year study will measure the fusion performance of the two biomaterials.

2 Jul 2010

Vitamin D inadequacy may cause metabolic syndrome among elderly people

A new study adds to the mounting evidence that older adults commonly have low vitamin D levels and that vitamin D inadequacy may be a risk factor for the metabolic syndrome, a condition that affects one in four adults. The results were presented at The Endocrine Society's 92nd Annual Meeting in San Diego.

2 Jul 2010

Two laboratory methods for Drosophila Neurobiology featured in Cold Spring Harbor Protocols journal

Cold Spring Harbor Laboratory's Neurobiology of Drosophila course (http://meetings.cshl.edu/courses/c-dros10.shtml) has served as the training ground for a generation of scientists tackling these complex problems. A new laboratory manual based on the protocols and background information taught in the course promises to spread these techniques to a wider audience. Two of the methods from the manual are featured in the July issue of the journal Cold Spring Harbor Protocols.

2 Jul 2010

Mice study may provide new insight on human pregnancies

The concept of pregnancy makes no sense-at least not from an immunological point of view. After all, a fetus, carrying half of its father's genome, is biologically distinct from its mother. The fetus is thus made of cells and tissues that are very much not "self"-and not-self is precisely what the immune system is meant to search out and destroy.

2 Jul 2010

Research may provide key to understanding interplay between exercise, aging and neurogenesis

Stem cells in the brain remain dormant until called upon to divide and make more neurons. However, little has been known about the molecular guards that keep them quiet.

2 Jul 2010

New asthma therapy shows promise for patients who do not respond to steroid treatments

A new nonsteroidal, anti-inflammatory therapy made from a human protein significantly decreases disease signs of asthma in mice, opening the possibility of a new asthma therapy for patients who do not respond to current steroid treatments. Results of this therapy in an animal model were presented at The Endocrine Society's 92nd Annual Meeting in San Diego.

2 Jul 2010

SAIC-Frederick, Fluidigm collaborate to decode entire genome of Epstein-Barr virus

SAIC-Frederick, Inc. and Fluidigm Corporation are collaborating to decode the entire genome of the Epstein-Barr virus (EBV) using technology that can speed up research on the genetic basis of cancer and other diseases.

1 Jul 2010

AMP comments on array-based cytogenetic tests at FDA's public meeting

Today, the Association for Molecular Pathology presented comments at the US Food & Drug Administration's public meeting on array-based cytogenetic tests. The FDA convened the meeting to seek answers to more than a dozen questions they had on how to evaluate the performance, interpret results and report findings of array-based cytogenetic tests for copy number variation.

1 Jul 2010

Oxycyte PFCE decreases mortality after onset of decompression sickness in porcine model study

Oxygen Biotherapeutics, Inc. today announced that results from U.S. Navy studies demonstrated decreased mortality in porcine animal models that were given an intravenous dose of Oxycyte® perfluorocarbon emulsion (PFCE) after the onset of decompression sickness (DCS). These results showed a statistically significant decrease in mortality compared with the control group that did not receive Oxycyte PFCE. This data was published in the June issue of Aviation Space and Environmental Medicine.

1 Jul 2010

Ronin, Hcf-1 bind together to control gene program that stimulates growth of stem cells

Ronin, crucial to the self-renewal of embryonic stem cells, and a co-regulator called Hcf-1, binds to a small strand of DNA called a hyperconserved enhancer element to control a gene "program" that stimulates growth of the stem cells and may even play a role in cancer, said a group of researchers led by Baylor College of Medicine in a current report in the journal Genes and Development.

1 Jul 2010

MPIB researcher makes methodical progress in the area of genetic code engineering

Proteins are the main actors in our body: They transport substances, convey messages or carry out vital processes in their role as molecular machines. The "helmsmen of the cell" are composed of amino acids, whose sequence is already defined by the heritable information in every living being. The translation of this information during the production of proteins (protein synthesis) is determined by the genetic code.

1 Jul 2010

Medical Science News

Histone H1 phosphorylation involved in control of ribosomal RNA gene transcription

Children's Hospital Boston researchers reprogram adult blood cells into iPS cells

Compugen's CGEN-15001 recombinant fusion protein abolishes spontaneous relapses in animal model of MS

Aushon BioSystems introduces new Human multiplex biomarker panels

Plant extract effective against ulcerative colitis in mice

Novel imaging agents and techniques can revolutionize medical imaging science: JNM

Frozen blood samples shows promise to study mechanism of blood disorders

FUISZ files new patent, receives notice of issuance for patent claims for blood analysis devices

DNA damage caused by UVA radiation leads to melanoma

Amedica, SUNY Upstate Medical University partner in comparative study of biomaterials

Vitamin D inadequacy may cause metabolic syndrome among elderly people

Two laboratory methods for Drosophila Neurobiology featured in Cold Spring Harbor Protocols journal

Mice study may provide new insight on human pregnancies

Research may provide key to understanding interplay between exercise, aging and neurogenesis

New asthma therapy shows promise for patients who do not respond to steroid treatments

SAIC-Frederick, Fluidigm collaborate to decode entire genome of Epstein-Barr virus

AMP comments on array-based cytogenetic tests at FDA's public meeting

Oxycyte PFCE decreases mortality after onset of decompression sickness in porcine model study

Ronin, Hcf-1 bind together to control gene program that stimulates growth of stem cells

MPIB researcher makes methodical progress in the area of genetic code engineering

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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