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Spanish researchers reprogram adult stem cells to help cardiac muscle regeneration

Spanish researchers have employed for the first time adult cells extracted from a human heart to turn stem cells from adipose tissue into cardiac myocytes. In other words, they achieved to "reprogram" adult stem cells, which might improve treatments for heart disease therapeutical.

20 May 2010

Boston University biomedical engineers develop new nanopore method for DNA sequencing

Sequencing DNA could get a lot faster and cheaper - and thus closer to routine use in clinical diagnostics - thanks to a new method developed by a research team based at Boston University. The team has demonstrated the first use of solid state nanopores - tiny holes in silicon chips that detect DNA molecules as they pass through the pore - to read the identity of the four nucleotides that encode each DNA molecule.

20 May 2010

Study shows plexiform lesion develops in experimental rat model of severe PAH

A new preclinical model of pulmonary arterial hypertension may lead to improved research and ultimately better therapies for this life-threatening problem, according to its developers, researchers at the University of South Alabama.

20 May 2010

Androgen receptors promote hepatitis B virus in growth and development of hepatoma cells

Dr. Ming-Heng Wu of the Institute of Basic Medical Sciences at National Cheng Kung University (NCKU), Taiwan, in collaboration with Prof. Chawnshang Chang's laboratory of University of Rochester (UR), United States, have discovered that androgen receptors (AR) can promote hepatitis B virus-induced hepatocarcinogenesis through modulation of hepatitis B virus (HBV) RNA transcription.

20 May 2010

New Agilent SurePrint G3 Gene Expression Microarrays introduced

Agilent Technologies Inc. today introduced Agilent SurePrint G3 Gene Expression Microarrays, providing up to one million features per standard 1-by-3-inch slide for added throughput, unique coverage which includes both coding and non-coding RNA, and cost effectiveness.

20 May 2010

Elevated levels of Lp-PLA2 associated with increased risk of coronary heart disease

A meta-analysis of approximately 80,000 individuals from 32 prospective studies was published in The Lancet on May 1, 2010. The data shows that elevated levels of lipoprotein-associated phospholipase A2 (Lp-PLA2), a vascular-specific inflammatory enzyme, are associated with an increased risk of coronary heart disease similar in magnitude to that with non-HDL cholesterol or systolic blood pressure.

20 May 2010

Role of neurotransmitter acetylcholine may suggest new treatment for Parkinson's disease: Researchers

Chicago and Montreal researchers studying the lowly lamprey eel have identified an overlooked nervous system pathway running parallel to known brainstem locomotor command circuitry in vertebrates such as birds, fishes and mammals.

20 May 2010

Live malaria parasites in the skin shut down immune responses and block vaccine function: Study

Why one after another new malaria vaccine tests well in the laboratory but fails in field trials has frustrated legions of malaria researchers, and has been the main stumbling block to malaria eradication. Now, a research team from Germany has unraveled that puzzle and shown that the problem is all about the skin and how it controls the immune system. The implications are profound.

20 May 2010

Mutation in BRCA1 tumor suppressor gene helps develop breast, ovarian cancer: Study

Studies have well established that women who harbor a mutation in the BRCA1 tumor suppressor gene are at greater risk for developing breast and ovarian cancers. Less known is information on other molecular events that may impact cancer formation in cells having a BRCA1 mutation. Investigators from The Cancer Institute of New Jersey and a number of major cancer centers in Europe have identified the role a key protein plays in helping cells with mutant BRCA1 genes to survive.

20 May 2010

Illusion challenges human visual system and brain

A new amazing illusion proves that defying gravity may be as simple as your point of view.

20 May 2010

New study shows CDPK1 controls toxoplasma's ability to secrete microneme proteins

Researchers at Washington University School of Medicine in St. Louis have identified a parasite protein that has all the makings of a microbial glass jaw: it's essential, it's vulnerable and humans have nothing like it, meaning scientists can take pharmacological swings at it with minimal fear of collateral damage.

20 May 2010

Trius awarded new DTRA contract for developing novel antibiotics against gram-negative bacterial pathogens

Trius Therapeutics, Inc. today announced that it has been awarded a new four and a half year contract from the Defense Threat Reduction Agency (DTRA), an agency within the U.S. Department of Defense, for the development of novel antibiotics directed against gram-negative bacterial pathogens. Trius may receive up to $29.5 million in support of development efforts under the new DTRA contract, which is funded as part of DTRA's Transformational Medical Technologies Initiative (TMTI).

20 May 2010

Zebrafish may help scientists reveal function of mysterious enzyme linked to steroid cortisol

Michael E. Baker, PhD, a researcher at the University of California, San Diego School of Medicine has discovered that zebrafish - an important animal model in disease and environmental studies - could provide the means to help scientists eventually reveal the function of a mysterious enzyme linked to the steroid cortisol, and found in the human brain.

20 May 2010

EPO rules in favor of Alnylam Pharmaceuticals’ Kreutzer-Limmer '945 patent

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today that the Board of Appeals of the European Patent Office (EPO) has ruled that claims of the Kreutzer-Limmer '945 (EP 1214945) patent meet needed requirements under European patent law. The '945 patent comprises broad claims covering the length and certain structural requirements for siRNAs that are important for advancement of RNAi therapeutics.

20 May 2010

Over-expression of Stat5 protein leads to deadly spread of prostate cancer: Study

Researchers from the Kimmel Cancer Center at Jefferson have found that Stat5, a signaling protein previously found to be key to survival of prostate cancer, is also involved in metastasis.

20 May 2010

UAMS and partners receive $14.7M NIH grant for extension of biomedical research

Biomedical research in Arkansas has received a $14.7 million boost over five years from the National Institutes of Health (NIH) to continue expanding and improving biomedical research in the state.

20 May 2010

Luminex, HTG launch qBead Gene Expression Assay

Luminex Corporation, the worldwide leader in multiplexed solutions, and High Throughput Genomics, Inc. (HTG), provider of the quantitative Nuclease Protection Assay (qNPA™), today launched a new custom gene expression product, the qBead Gene Expression Assay (qBead Assay). The companies co-developed the product and have signed an exclusive distribution agreement in which Luminex will begin offering it to the research community.

From Luminex 20 May 2010

Gene therapy shows positive effects in rat models of PAH: Researchers

Gene therapy has been shown to have positive effects in rat models of pulmonary arterial hypertension, according to researchers at the University of Adelaide in Australia.

20 May 2010

Curis announces inclusion in NASDAQ Biotechnology Index

Curis, Inc., a drug development company seeking to develop next generation targeted small molecule drug candidates for cancer treatment, today announced that it has been selected for addition to the NASDAQ Biotechnology Index (NBI), which will become effective prior to market open on Monday, May 24, 2010.

19 May 2010

Essen BioScience launches CellPlayer Cell Migration 96-well assay kit

Essen BioScience Inc., a global provider of life science research tools and discovery services, today announced the launch of its CellPlayer™ Cell Migration 96-well assay kit for the IncuCyte™ Live-Cell Imaging System. The expanding line of kinetic CellPlayer assays for the IncuCyte also includes a co-culture assay for Angiogenesis.

From Sartorius 19 May 2010

Medical Science News

Spanish researchers reprogram adult stem cells to help cardiac muscle regeneration

Boston University biomedical engineers develop new nanopore method for DNA sequencing

Study shows plexiform lesion develops in experimental rat model of severe PAH

Androgen receptors promote hepatitis B virus in growth and development of hepatoma cells

New Agilent SurePrint G3 Gene Expression Microarrays introduced

Elevated levels of Lp-PLA2 associated with increased risk of coronary heart disease

Role of neurotransmitter acetylcholine may suggest new treatment for Parkinson's disease: Researchers

Live malaria parasites in the skin shut down immune responses and block vaccine function: Study

Mutation in BRCA1 tumor suppressor gene helps develop breast, ovarian cancer: Study

Illusion challenges human visual system and brain

New study shows CDPK1 controls toxoplasma's ability to secrete microneme proteins

Trius awarded new DTRA contract for developing novel antibiotics against gram-negative bacterial pathogens

Zebrafish may help scientists reveal function of mysterious enzyme linked to steroid cortisol

EPO rules in favor of Alnylam Pharmaceuticals’ Kreutzer-Limmer '945 patent

Over-expression of Stat5 protein leads to deadly spread of prostate cancer: Study

UAMS and partners receive $14.7M NIH grant for extension of biomedical research

Luminex, HTG launch qBead Gene Expression Assay

Gene therapy shows positive effects in rat models of PAH: Researchers

Curis announces inclusion in NASDAQ Biotechnology Index

Essen BioScience launches CellPlayer Cell Migration 96-well assay kit

The Proteoform Puzzle: Unlocking the Next Frontier

Synthetic Biology and the Pursuit of Living Diagnostics

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

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