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Mutations in several genes associated with developmental brain disorder: Study

Although there is no known cause of autism, studies have shown that mutations in several genes are associated with the developmental brain disorder. New research has uncovered two additional genes that may be involved with autism.

3 May 2010

McGill scientist discovers how one particular gene regulates epithelial cells

New research led by McGill Biochemist Dr. William Muller helps explain why breast-milk cells lose their structure, causing them to clump up in strange ways (photos available) and sometimes become cancer tumors. With the support of Chen Ling and Dongmei Zuo at McGill's Goodman Cancer Centre, Muller has discovered how one particular gene regulates epithelial cells - cells that normally form in sheets and are polarized to enable the transport of molecules in a single direction.

30 Apr 2010

Research shows microRNA can silence genes that protect genome from cancer-causing mutations

New research shows for the first time that molecules called microRNA can silence genes that protect the genome from cancer-causing mutations.

30 Apr 2010

Pieris AG announces preclinical data for proprietary PRS-110 Anticalin compound

Pieris AG announced today preclinical data for its proprietary PRS-110 Anticalin compound, which targets the c-Met receptor, demonstrating a dose-dependant reduction of tumor growth in a xenograft mouse model.

30 Apr 2010

Study finds multiple brain regions used to decipher sentences

A new study from the University of Rochester finds that there is no single advanced area of the human brain that gives it language capabilities above and beyond those of any other animal species.

30 Apr 2010

Liver transplant recipients develop premature immune senescence: Researchers

Researchers at the University of Cambridge found that liver transplant recipients develop premature immune senescence, the normal process by which the immune system ages and becomes less effective. Full details appear in the May issue of Liver Transplantation, a journal published by Wiley-Blackwell on behalf of the American Association for the Study of Liver Diseases.

30 Apr 2010

Researchers experiment different nanoparticles that may help surgeons remove glioblastomas

Researchers have developed a way to enhance how brain tumors appear in MRI scans and during surgery, making the tumors easier for surgeons to identify and remove.

30 Apr 2010

HemCon Medical Technologies to ask for reversal of jury verdict in chitosan patent case

HemCon Medical Technologies, Inc., announced today that it will ask a US District Court in New Hampshire to review and reverse a jury verdict based on a patent held by Marine Polymer Technologies, Inc. The jury awarded damages of $29.4 million against HemCon in the patent case. HemCon will ask the Court to review the validity of the patent and reverse the damage award.

30 Apr 2010

Researchers use healthy person's complete genome sequence to predict risk for dozens of diseases

For the first time, researchers have used a healthy person's complete genome sequence to predict his risk for dozens of diseases and how he will respond to several common medications. The risk analysis, from the Stanford University School of Medicine, also incorporates more-traditional information such as a patient's age and gender and other clinical measurements.

30 Apr 2010

Short-term calorie restriction improves function of T-cells

Scientists funded by the Agricultural Research Service (ARS) found that volunteers who followed a low-calorie diet or a very low-calorie diet not only lost weight, but also significantly enhanced their immune response. The study may be the first to demonstrate the interaction between calorie restriction and immune markers among humans.

30 Apr 2010

Researchers identify new genetic link to systemic scleroderma

An international research consortium including scientists from The University of Texas Health Science Center at Houston (UTHealth) has identified a new genetic link to the systemic form of scleroderma. Researchers believe a thorough understanding of the genetic nature of the disease is crucial to developing a cure.

30 Apr 2010

Whole-genome analysis may play future role in clinical medicine: Study

Scientists at Stanford and Harvard Universities collaborated to assess the clinical usefulness of analyzing a patient's full genome for disease risks and unusual drug responses. The work brings closer to reality the concept that whole-genome sequencing might one day play a clinical role.

30 Apr 2010

Excess urinary protein excretion increases risk of kidney, heart complications in people with hypertension

Healthy people with high blood pressure who excrete a slight excess of protein in the urine raise their risk of developing kidney and heart complications. According to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (CJASN), more attention should focus on the potential health effects of urinary protein excretion in individuals with high blood pressure (hypertension).

30 Apr 2010

Jumping elements in primates may have important consequences for studies of human genetic diseases

The density of transposable (jumping) elements between sex chromosomes in primates may have important consequences for the studies of human genetic diseases, say Penn State University researchers.

30 Apr 2010

Manipulating physiology of "kissing bug" may help prevent transmission of Chagas' disease

It makes your skin crawl-a bug that crawls onto your lips while you sleep, drawn by the exhaled carbon dioxide, numbs your skin, bites, then gorges on your blood. And if that's not insult enough, it promptly defecates on the wound-and passes on a potentially deadly disease.

30 Apr 2010

CBC, Scarab Genomics form agreement to increase manufacturing yield of Solinex rhu-pGSN

Critical Biologics Corporation (CBC) and Scarab Genomics announced today a strategic agreement to substantially increase the manufacturing yield of CBC's lead therapeutic protein candidate, Solinex™, an intravenous formulation of recombinant human plasma gelsolin (rhu-pGSN).

30 Apr 2010

Study identifies extracapsular LNI as a negative prognostic factor for esophageal cancer

There is increasing evidence to include combined neoadjuvant chemoradiotherapy (CRT) as an alternative to surgical resection alone, to improve survival for locoregional esophageal cancer. More recently, attention has focused on the presence of extracapsular lymph node involvement (LNI), which identifies a subgroup of patients with significantly worse long-term survival. Little is known about the effects of neoadjuvant chemoradiotherapy (CRT) on the presence of extracapsular LNI and its prognostic value in patients with resected esophageal cancer.

30 Apr 2010

microRNAs serve as biomarkers for lung tumor classification: Study

Rosetta Genomics, Ltd., a leading developer and provider of microRNA-based molecular diagnostic tests, announces the publication of a study showing microRNA expression differentiates between primary lung tumors and metastases to the lung. The study, entitled, "MicroRNA expression differentiates between primary lung tumors and metastases to the lung," was published in the online edition of Pathology Research and Practice on April 28, 2010.

30 Apr 2010

iPierian receives $1.5M Basic Biology Award from CIRM to study cellular reprogramming

iPierian, Inc., the leading company focused on creating new therapeutics discovered using cellular reprogramming and directed differentiation of patient cells, today announced that it has been awarded a three-year $1.5 million "Basic Biology Award" from the California Institute of Regenerative Medicine.

30 Apr 2010

Low vitamin D levels may be associated with physical disability, cognitive impairment in MS patients

Low vitamin D levels may be associated with more advanced physical disability and cognitive impairment in persons with multiple sclerosis, studies conducted by neurologists at the University at Buffalo have shown.

30 Apr 2010

Medical Science News

Mutations in several genes associated with developmental brain disorder: Study

McGill scientist discovers how one particular gene regulates epithelial cells

Research shows microRNA can silence genes that protect genome from cancer-causing mutations

Pieris AG announces preclinical data for proprietary PRS-110 Anticalin compound

Study finds multiple brain regions used to decipher sentences

Liver transplant recipients develop premature immune senescence: Researchers

Researchers experiment different nanoparticles that may help surgeons remove glioblastomas

HemCon Medical Technologies to ask for reversal of jury verdict in chitosan patent case

Researchers use healthy person's complete genome sequence to predict risk for dozens of diseases

Short-term calorie restriction improves function of T-cells

Researchers identify new genetic link to systemic scleroderma

Whole-genome analysis may play future role in clinical medicine: Study

Excess urinary protein excretion increases risk of kidney, heart complications in people with hypertension

Jumping elements in primates may have important consequences for studies of human genetic diseases

Manipulating physiology of "kissing bug" may help prevent transmission of Chagas' disease

CBC, Scarab Genomics form agreement to increase manufacturing yield of Solinex rhu-pGSN

Study identifies extracapsular LNI as a negative prognostic factor for esophageal cancer

microRNAs serve as biomarkers for lung tumor classification: Study

iPierian receives $1.5M Basic Biology Award from CIRM to study cellular reprogramming

Low vitamin D levels may be associated with physical disability, cognitive impairment in MS patients

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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