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People with body dysmorphic disorder have difficulties in processing visual input, say UCLA researchers

Everyone checks themselves in the mirror now and then, but that experience can be horrifying for individuals suffering from body dysmorphic disorder, or BDD, a psychiatric condition that causes them to believe, wrongly, that they appear disfigured and ugly. These people tend to fixate on minute details - every tiny blemish looms huge - rather than viewing their face as a whole.

2 Feb 2010

New research shows tumor suppressor p53 prevents cancer progression in cells

Cells missegregate a chromosome approximately once every hundred divisions. But don't be too alarmed: new research in the Journal of Cell Biology shows that the tumor suppressor p53 limits the growth of cells with incorrect numbers of chromosomes and prevents their progression toward cancer.

2 Feb 2010

Study: Schizophrenia patients may experience beneficial brain changes in response to exercise

Potentially beneficial brain changes (an increase in the volume of an area known as the hippocampus) occur in response to exercise both in patients with schizophrenia and healthy controls, according to a report in the February issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

1 Feb 2010

Researchers design bioactive nanomaterial that promotes cartilage growth

Northwestern University researchers are the first to design a bioactive nanomaterial that promotes the growth of new cartilage in vivo and without the use of expensive growth factors. Minimally invasive, the therapy activates the bone marrow stem cells and produces natural cartilage.

1 Feb 2010

University of Pittsburgh awarded $3.5M NIH grant for WaferGen Biosystems's SmartChip Real-Time PCR System

WaferGen Biosystems, Inc., a leading developer of state-of-the-art genetic analysis systems, today announced that the National Institutes of Health (NIH) awarded a grant to the University of Pittsburgh that includes funding of $350,000 over the grant period for WaferGen's SmartChip™ Real-Time PCR System. The researchers will conduct novel gene expression research in the areas of advanced lung disease and asthma and will use the SmartChip system as the key platform for high throughput validation.

1 Feb 2010

Patients with rare autoimmune disease produce antibodies that disarm immune proteins

Two studies published online on February 1 in the Journal of Experimental Medicine (www.jem.org) reveal that patients with a rare autoimmune disease produce antibodies that attack microbe-fighting immune proteins called cytokines.

1 Feb 2010

Belfast scientists identify gene that can help predict tamoxifen treatment failure

Scientists in Belfast have identified a gene which could predict whether women with breast cancer will respond to treatment with tamoxifen, according to findings published today in Cancer Research.

1 Feb 2010

Asuragen enters into research agreements to develop microRNA-based diagnostic test

Asuragen, Inc., a leader in molecular diagnostics and RNA-based pharmacogenomics services, announced today that it has entered into research agreements with The University of Pittsburgh Medical Center, Brigham and Women’s Hospital, the H. Lee Moffitt Cancer Center, Dartmouth’s Hitchcock Medical Center and the University of Sherbrooke to develop a microRNA-based diagnostic test to aid the detection of pancreatic cancer from fine-needle aspirate (FNA) biopsies.

1 Feb 2010

Epigenetics may help determine CT radiation risk to patients' offsprings

There remains a lack of consensus amongst the medical and scientific communities about any cancer risk from low level radiation, particularly low-dose radiation delivered from computed tomography (CT) scans. However, the study of epigenetics may play a role in determining whether or not future trends of diseases can in fact be linked to utilization of CT, according to an article in the February issue of the Journal of the American College of Radiology (JACR).

1 Feb 2010

Study indicates dogs make excellent models for studying human genetic disorders

In the new Swedish-Finnish study, published in Nature Genetics, the researchers identified five loci that predispose to an SLE-related disease in Nova Scotia duck tolling retrievers.

31 Jan 2010

USPTO allows claims to Rosetta Genomics' two microRNA related patent applications

Rosetta Genomics today announced that the United States Patent and Trademark Office has allowed claims in two patent applications.

30 Jan 2010

Delaware Bio members support bioscience educational initiatives

Last night at the second annual Delaware Bio Winterfest, Delaware BioScience Association provided the Junior Achievement of Delaware with financial support of $6555.00 to aid in the outfitting of the new Innovation hub.

30 Jan 2010

Noninvasive optical imaging probes to determine amount and type of cell death in tumors

For quite some time, the "Holy Grail" in medical imaging has been the development of an effective method to image cell death as a means to intervene early in diseases and rapidly determine the effectiveness of treatments. A new paper by researchers at the University of Notre Dame and the Washington University School of Medicine describes important progress in using a synthetic probe to target dead and dying cells in mammary and prostate tumors in living animals.

30 Jan 2010

Musical video to teach basics of biotechnology

The video will be made available to high school students across North Carolina to help teach them how biotechnology harnesses cellular machinery to cure diseases, detect biohazards and manufacture new materials.

30 Jan 2010

Pathway Genomics' genetic health report provides valuable insight into certain health conditions

In the past few years, the science of genetic testing has advanced exponentially, both in the amount of information genetic testing can reveal and the precision and reliability of the results.

30 Jan 2010

Study may lead to preventative and therapeutic treatments for MS patients

Previous studies have shown multiple sclerosis (MS) patients are more often born in spring than in any other season, indicating that there is an environmental risk factor for the disease. A paper in the journal Neurology, reviewed for f1000 Medicine by Emmanuelle Waubant and Ellen Mowry, now suggests that this seasonal effect is mediated by the gene HLA-DRB1.

30 Jan 2010

New biomarker may predict treatment outcomes in RA patients

Investigators have identified a biomarker that could help doctors select patients with rheumatoid arthritis who will benefit from therapy with drugs such as Enbrel, a tumor necrosis factor (TNF)-antagonist drug.

30 Jan 2010

Docking algorithm EADock allows successful design of new inhibitors for anti-cancer target

Many human tumors express indoleamine 2,3-dioxygenase (IDO), an enzyme which mediates an immune-escape in several cancer types. Researchers in the Molecular Modeling group at the SIB Swiss Institute of Bioinformatics and Dr. Beno-t J. Van den Eynde's group at the Ludwig Institute for Cancer Research Ltd (LICR) Brussels Branch developed an approach for creating new IDO inhibitors by computer-assisted structure-based drug design. The study was presented in the January 2010 online issue of the Journal of Medicinal Chemistry.

30 Jan 2010

New study identifies that SynDIG1 plays critical role in creating and sustaining synapses

A new study from UC Davis Health System identifies for the first time a brain protein called SynDIG1 that plays a critical role in creating and sustaining synapses, the complex chemical signaling system responsible for communication between neurons.

30 Jan 2010

New mathematical model helps in predicting treatment outcomes for cervical cancer patients

Cervical cancer is highly curable when caught early. But in a third of cases, the tumor responds poorly to therapy or recurs later, when cure is much less likely.

29 Jan 2010

Medical Science News

People with body dysmorphic disorder have difficulties in processing visual input, say UCLA researchers

New research shows tumor suppressor p53 prevents cancer progression in cells

Study: Schizophrenia patients may experience beneficial brain changes in response to exercise

Researchers design bioactive nanomaterial that promotes cartilage growth

University of Pittsburgh awarded $3.5M NIH grant for WaferGen Biosystems's SmartChip Real-Time PCR System

Patients with rare autoimmune disease produce antibodies that disarm immune proteins

Belfast scientists identify gene that can help predict tamoxifen treatment failure

Asuragen enters into research agreements to develop microRNA-based diagnostic test

Epigenetics may help determine CT radiation risk to patients' offsprings

Study indicates dogs make excellent models for studying human genetic disorders

USPTO allows claims to Rosetta Genomics' two microRNA related patent applications

Delaware Bio members support bioscience educational initiatives

Noninvasive optical imaging probes to determine amount and type of cell death in tumors

Musical video to teach basics of biotechnology

Pathway Genomics' genetic health report provides valuable insight into certain health conditions

Study may lead to preventative and therapeutic treatments for MS patients

New biomarker may predict treatment outcomes in RA patients

Docking algorithm EADock allows successful design of new inhibitors for anti-cancer target

New study identifies that SynDIG1 plays critical role in creating and sustaining synapses

New mathematical model helps in predicting treatment outcomes for cervical cancer patients

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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