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DNA-based assembly line for precision nano-cluster construction

Building on the idea of using DNA to link up nanoparticles - particles measuring mere billionths of a meter - scientists at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory have designed a molecular assembly line for predictable, high-precision nano-construction.

29 Mar 2009

Evolutionary origin of bacterial chromosomes revealed

Researchers have unveiled the evolutionary origin of the different chromosomal architectures found in three species of Agrobacterium.

29 Mar 2009

Polymer nanowires detect cancer biomarker

Investigators at the University of California, Riverside, have developed a simple and cost-effective method of building conducting polymer nanowires that can detect a wide range of levels of a cancer biomarker. This work, which was published in the journal Analytical Chemistry, could serve as a model for portable cancer detection equipment suitable for use in a doctor's office.

26 Mar 2009

Nanoparticles open door to cancer prevention

Perhaps the best way to fight cancer is to prevent it from developing in the first place, and based on newly published research from investigators at the University of Wisconsin-Madison, nanoparticles may be able to make cancer chemoprevention a reality.

26 Mar 2009

Safer nanoparticles spotlight tumors, deliver drugs

Small is promising when it comes to illuminating tiny tumors or precisely delivering drugs, but many worry about the safety of nanoscale materials.

26 Mar 2009

Twin nanoparticle shown effective at targeting, killing breast cancer cells

A team of investigators at Brown University has developed a novel way to treat a class of breast cancer cells. The team has created twin nanoparticles that specifically targets the Her-2 tumor cell and unload a cancer-fighting drug directly into it. The result is a boost in antitumor activity while minimizing side effects. The findings of this study have been published in the Journal of the American Chemical Society.

26 Mar 2009

Nanoparticles deliver gene therapy, killing tumors

Given that cancer is ultimately a genetic disease, it has long been the hope of researchers to use gene therapy to attack tumors where they might be most susceptible.

26 Mar 2009

Food choices evolve through information overload

Ever been so overwhelmed by a huge restaurant menu that you end up choosing an old favourite instead of trying something new?

24 Mar 2009

Time (and PPAR-beta/delta) heals all wounds

Mammalian skin requires constant maintenance, but how do skin cells know when to proliferate and at what rate?

23 Mar 2009

Study shows how Salmonella survives in environment

Scientists at the University of Liverpool have demonstrated how a single-celled organism, living freely in the environment, could be a source of Salmonella transmission to animals and humans.

23 Mar 2009

Rewrite of the recipe for life - new type of DNA

In a dramatic rewrite of the recipe for life, scientists from Florida today described the design of a new type of DNA with 12 chemical letters instead of the usual four.

23 Mar 2009

Scientists make a new protein from scratch

No doubt proteins are complex. Most are "large" and full of interdependent branches, pockets and bends in their final folded structure.

23 Mar 2009

DNA duplication - mechanism for 'survival of the fittest'

Some 65 million years ago, the earth's most recent 'mass extinction' took place.

23 Mar 2009

Scientists find molecular mechanisms linking sugar production and longevity

Johns Hopkins researchers have discovered a new energy-making biochemical twist in determining the lifespan of yeast cells, one so valuable to longevity that it is likely to also functions in humans.

23 Mar 2009

Hollow gold nanospheres show promise in cancer therapy

A new metal nanostructure developed by researchers at the University of California, Santa Cruz, has already shown promise in cancer therapy studies and could be used for chemical and biological sensors and other applications as well.

22 Mar 2009

Quantum effect may hold promise for low-cost DNA sequencing, sensor applications

A ghostly property of matter, called quantum tunneling, may aid the quest for accurate, low-cost genomic sequencing, according to a new paper in Nature Nanotechnology Letters by Stuart Lindsay and his collaborators at the Biodesign Institute of Arizona State University.

22 Mar 2009