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Comprehensive analysis of immune checkpoint inhibitors reveals endocrine toxicity patterns

Announcing a new publication for Acta Materia Medica journal. Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment but pose a challenge of immune-related adverse events (irAEs), particularly endocrine toxicity, that can severely compromise patient well-being.

21 Feb 2024

Intramolecular bivalent glues: A promising avenue for protein degradation

Living cells resemble highly organized small towns - in addition to energy production, transportation systems, and construction, cells also require efficient waste disposal.

21 Feb 2024

Digital DNA melting analysis can be a faster and more reliable tool for pathogen detection

A new analysis method can detect pathogens in blood samples faster and more accurately than blood cultures, which are the current state of the art for infection diagnosis.

21 Feb 2024

Cycles of a diet that mimics fasting can reduce signs of immune system aging, as well as insulin resistance and liver fat

A recent study showed that three cycles of a fasting-mimicking diet in adults were associated with lower pre-diabetes markers, lower hepatic fat, and a higher lymphoid-to-myeloid ratio, which is an indicator of the aging of the immune system.

21 Feb 2024

Study exposes food insecurity among graduate students and postdocs

A new study in JAMA Network Open reports on this phenomenon at three Harvard, Boston, Massachusetts, campuses.

21 Feb 2024

Individual genetic variations and bacterial flora linked to recurrent caries disease

Researchers at Umeå University have for the first time been able to show that individual variation in susceptibility to infection and bacterial flora together explain recurrent caries disease and that others are asymptomatic.

21 Feb 2024

New mechanism discovered: B cells' contribution to immune tolerance in thymus gland

Immune cells must learn not to attack the body itself. A team of researchers from the Technical University of Munich (TUM) and the Ludwig Maximilian University of Munich (LMU) has discovered a previously unknown mechanism behind this: other immune cells, the B cells, contribute to the "training" of the T cells in the thymus gland.

21 Feb 2024

UNC Lineberger selected as one of the research site for NCI's Cancer Screening Research Network

UNC Lineberger Comprehensive Cancer Center has been selected as one of nine national research sites for the National Cancer Institute's (NCI), part of the National Institutes of Health, newly launched Cancer Screening Research Network (CSRN), which will evaluate promising and emerging cancer screening technologies.

21 Feb 2024

Are you a weekend warrior when it comes to exercise? Both regular or one-to-two days of exercise aid weight loss

A new study in Obesity compares these two trends with inactivity to assess their effectiveness.

21 Feb 2024

Novel open-source platform can learn and predict user-defined behaviors from video data

Researchers from Carnegie Mellon University, the University Hospital Bonn and the University of Bonn have created an open-source platform known as A-SOiD that can learn and predict user-defined behaviors, just from video.

21 Feb 2024

Scientists develop 3D-printable gelatin materials for reconstructive and plastic surgery

Researchers from IOCB Prague and Ghent University have been working on improving the properties of gelatin-based materials, thereby expanding the possibilities of their use mainly in medicine.

21 Feb 2024

NIH grant boosts research on biofilm dispersal in wound infections

Most chronic wound infections share one thing in common: the presence of biofilms, which are composed of many different microorganisms that congregate as a mass, usually on some type of surface such as a wound bed.

21 Feb 2024

Nose cartilage-based knee joint treatment project receives €2.3 million funding

Treating knee joint defects with cartilage from the nose: The University Hospital in Würzburg is working on the approval of this procedure.

21 Feb 2024

Female ginseng compound holds promise as osteoporosis treatment

With ever-increasing life expectancy comes the challenge of treating age-related disorders such as osteoporosis.

21 Feb 2024

Study reveals sleep's role in consolidating complex memories

Sleep helps consolidate our memory of complex associations, thus supporting the ability to complete memories of whole events.

21 Feb 2024

Physical inactivity and inflammation drive age-related gene changes in skeletal muscles

New research indicates that some age-related changes in gene and protein expression in the skeletal muscles of older individuals may be affected more by physical inactivity and chronic inflammation than primary aging, or intrinsic maturational processes.

21 Feb 2024

Medical Science News

Comprehensive analysis of immune checkpoint inhibitors reveals endocrine toxicity patterns

Intramolecular bivalent glues: A promising avenue for protein degradation

Digital DNA melting analysis can be a faster and more reliable tool for pathogen detection

Cycles of a diet that mimics fasting can reduce signs of immune system aging, as well as insulin resistance and liver fat

Study exposes food insecurity among graduate students and postdocs

Individual genetic variations and bacterial flora linked to recurrent caries disease

New mechanism discovered: B cells' contribution to immune tolerance in thymus gland

UNC Lineberger selected as one of the research site for NCI's Cancer Screening Research Network

Are you a weekend warrior when it comes to exercise? Both regular or one-to-two days of exercise aid weight loss

Novel open-source platform can learn and predict user-defined behaviors from video data

Scientists develop 3D-printable gelatin materials for reconstructive and plastic surgery

NIH grant boosts research on biofilm dispersal in wound infections

Nose cartilage-based knee joint treatment project receives €2.3 million funding

Female ginseng compound holds promise as osteoporosis treatment

Study reveals sleep's role in consolidating complex memories

Physical inactivity and inflammation drive age-related gene changes in skeletal muscles

Mitochondrial activation enhances cardiac regeneration therapy

Microplastics detected in all human placenta samples

Scientists uncover brain mechanisms for social memory recall in mice

Does your lifestyle increase your risk of IBS?

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

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