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NIH grant to fund development of new gene therapy platform for brain diseases

A two-phase NIH grant will fund research into a new CRISPR-based gene therapy platform that will target genetic brain diseases like Angelman syndrome and H1-4 (HIST1H1E) syndrome.

3 Oct 2023

New discovery could delay relapse in triple-negative breast cancer

A team of researchers at the Medical University of Vienna has discovered that dormant tumor cells surviving chemotherapy can be targeted through the inhibition of a specific protein called P-glycoprotein (P-gp).

3 Oct 2023

Study identifies potential drug target for lymphedema

The human lymphatic system consists of a vast network of vessels that drain protein-rich fluid in tissues and transport it to lymph nodes.

3 Oct 2023

Genetic testing of one thousand embryos provides insights into human development and IVF

By genetically testing nearly one thousand embryos, scientists have provided the most detailed analysis of embryo fate following human in vitro fertilization.

3 Oct 2023

Brain activity changes depending on context, even when performing the same action

Standing at a crosswalk, the signal changes from "don't walk," to "walk." You might step out into the street straight away, or you might look both ways before you cross.

3 Oct 2023

SARS-CoV-2 infection in coronary vessels linked to cardiovascular complications

Researchers reported that the increased long-term risk of acute cardiovascular complications associated with COVID-19 is linked to SARS-CoV-2 infecting coronary vessels and inducing the formation of plaques.

3 Oct 2023

Breaking the cycle of chronic back pain: new study reveals the power of shifting pain beliefs

Researchers examined whether pain processing therapy involving the reattribution of pain to processes of the brain or mind instead of being indicative of tissue damage or injury could bring pain relief and help improve the recovery process.

3 Oct 2023

New hope for hispanic type 2 diabetes patients: pharmacist intervention cuts A1c levels

Researchers examined whether pharmacist-led interventions improved adherence to medications and guideline-concordant care based on changes in hemoglobin A1C (HbA1C) levels and systolic blood pressure among Hispanic type 2 diabetes patients.

3 Oct 2023

Microglial states and their impact on Alzheimer's disease

Researchers examined 152,459 microglial transcriptomes from 443 individuals, identifying 12 transcriptional states and their relationship to Alzheimer's disease.

3 Oct 2023

Novel deep learning model to assess Alzheimer's disease progression risk

Patterns in the Alzheimer's disease (AD) trajectory using Mendelian randomization (MR) and deep learning (DL).

3 Oct 2023

Identification of Alzheimer's disease-associated micro-RNA biomarkers through network-based analysis

Micro-ribonucleic acids (miRNAs) linked to cognition and Alzheimer's disease (AD).

3 Oct 2023

Could dark chocolate improve the gut health of athletes?

The effect of cocoa polyphenols on intestinal permeability.

3 Oct 2023

Is climate change turning up the heat on China's aging population?

Rising temperatures and an aging population in China exacerbate heat-related mortality risks, new study finds. The research highlights the urgent need for policies that address both cold and heat-related health risks among the elderly.

2 Oct 2023

Cannabis legalization leads to surprising shifts in youth usage patterns

This JAMA Network Open study examines the impact of cannabis legalization on high-risk young adults in Ontario, Canada, revealing mixed results. While frequent users reduced their cannabis use post-legalization, leading to fewer adverse consequences, those who were non-users before legalization slightly increased their use over time.

2 Oct 2023

GPT-4 beats human doctors in medical soft skills

Researchers evaluated how well AI models GPT-4 and ChatGPT perform on the US Medical Licensing Examination questions focused on soft skills like judgment and empathy. GPT-4 outperformed both ChatGPT and human test-takers, answering 90% of questions correctly, while ChatGPT had a 62.5% accuracy rate.

2 Oct 2023

Could seaweeds be the superfood and medicine of the future?

Researchers consolidate the diverse nutritional and medicinal benefits of seaweeds, touting their potential in food, nutraceuticals, and pharmaceuticals. The study also highlights challenges and opportunities in industrial applications, calling for more research to optimize extraction and refinement processes.

2 Oct 2023

Eat by the clock: How meal timing tunes your liver's circadian rhythm

A study in Nature Communications delves into how the liver's circadian clock responds to meal timing, impacting fat metabolism and other bodily processes. The research underscores the intricate network that contributes to liver's diurnal rhythms, regulated by protein phosphorylation and nutrient availability.

2 Oct 2023

Compulsive stress coping behaviors linked to brain's dopamine-dependent habit system

Researchers performed longitudinal studies in rats to measure the sensitivity of early established versus compulsive polydipsic alcohol (or water) drinking in response to bilateral infusion of α-flupentixol, anterior dorsolateral striatum (aDLS)-dopamine (DA) receptor antagonist.

2 Oct 2023

Teaching toddlers to cook boosts self-control and healthy eating habits, new study reveals

Researchers presented the findings of a randomized controlled trial evaluating the effects of Recipe 4 Success, a preventive intervention implemented across seven cities, villages, and towns of Wisconsin and Pennsylvania in the USA.

2 Oct 2023

Cannabis use disorder linked to ~60% higher risk of adverse cardiovascular events, Canadian study finds

A recent study published in Addiction evaluated the associations of cannabis use disorder (CUD) with cardiovascular disease (CVD) outcomes.

2 Oct 2023

Medical Science News

NIH grant to fund development of new gene therapy platform for brain diseases

New discovery could delay relapse in triple-negative breast cancer

Study identifies potential drug target for lymphedema

Genetic testing of one thousand embryos provides insights into human development and IVF

Brain activity changes depending on context, even when performing the same action

SARS-CoV-2 infection in coronary vessels linked to cardiovascular complications

Breaking the cycle of chronic back pain: new study reveals the power of shifting pain beliefs

New hope for hispanic type 2 diabetes patients: pharmacist intervention cuts A1c levels

Microglial states and their impact on Alzheimer's disease

Novel deep learning model to assess Alzheimer's disease progression risk

Identification of Alzheimer's disease-associated micro-RNA biomarkers through network-based analysis

Could dark chocolate improve the gut health of athletes?

Is climate change turning up the heat on China's aging population?

Cannabis legalization leads to surprising shifts in youth usage patterns

GPT-4 beats human doctors in medical soft skills

Could seaweeds be the superfood and medicine of the future?

Eat by the clock: How meal timing tunes your liver's circadian rhythm

Compulsive stress coping behaviors linked to brain's dopamine-dependent habit system

Teaching toddlers to cook boosts self-control and healthy eating habits, new study reveals

Cannabis use disorder linked to ~60% higher risk of adverse cardiovascular events, Canadian study finds

Fourier 80: bringing benchtop NMR systems to the laboratory

How industrial hygiene flow calibration supports defensible exposure data

How electrical engineering ensures accurate calibration and patient safety

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