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New collection of month-specific infant brain atlas captures fine details of the early developing brain

Human brain atlases can be used by medical professionals to track normative trends over time and to pinpoint crucial aspects of early brain development.

26 Jan 2023

Persistent tumor mutation burden linked with therapeutic response to immunotherapy

Cancer experts have tried, sometimes unsuccessfully, to use the total number of mutations in a tumor, called the tumor mutation burden (TMB), to predict a patient's response to immunotherapy.

26 Jan 2023

PLK1-mTOR axis may be a promising therapeutic target for sepsis, study suggests

Sepsis, one of the most acute and serious disease complications in the intensive care unit, is caused by various infections and results in life-threatening organ dysfunction.

26 Jan 2023

Using artificial human skin to block invasive growth in a skin cancer model

By using artificial human skin, a research group from the University of Copenhagen have managed to block invasive growth in a skin cancer model.

26 Jan 2023

Researchers discover the impact of microRNA on inflammation in lupus

A group of researchers from the Graduate School of Medicine at Nagoya University in Japan have discovered the impact of microRNA (miRNA) on inflammation in lupus in mice.

26 Jan 2023

Study reveals the inevitability of Zika virus dumbbell-1 structure for viral pathogenesis

In a recent study posted to the bioRxiv* preprint server, researchers designed two dumbbell-1 (DB-1) mutant Zika virus (ZIKV) infectious clones termed ZIKV-TL.PK and ZIKV-p.2.5’.

26 Jan 2023

Prenatal MRI helps visualize SARS-CoV-2 infection-induced abnormalities in the placenta and fetuses

Researchers performed a prospective case-control study on pregnant women with confirmed coronavirus disease 2019 (COVID-19).

26 Jan 2023

Researchers report on a genome-wide reconstruction of human microbes to develop personalized therapies

Researchers reported on AGORA2, an expansion of their previously published resource, AGORA, of genomewide metabolic reconstructions of human intestinal microbes.

26 Jan 2023

Study shows improved host health by modulating intestinal microbiota

Researchers presented intestinal microbiota modulation as a probable therapeutic option for diseases such as Crohn’s disease (CD).

26 Jan 2023

Researchers develop a new multi-omics microsampling method for complete health profiling

Researchers developed a multi-omics-based microsampling workflow for profiling proteins, metabolites, lipids, and specific cytokines and hormones, i.e., multiple analytes, in a single blood sample of 10 μl (microsample).

26 Jan 2023

Do individuals with acute attitudes toward science over-estimate their understanding of scientific matters?

Researchers investigated whether individuals with extreme attitudes, negative or positive, show a greater likelihood of believing that they understand science and whether the trends in attitudes were contingent on technological specifications.

26 Jan 2023

New therapy-relevant marker may help identify ER+ breast cancer patients who may benefit from immunotherapies

A multi-institutional team led by scientists from the Medical College of Wisconsin Cancer Center has discovered PD-L2 as a therapy-relevant marker to identify patients with estrogen receptor-positive breast cancer who may benefit from new immunotherapies.

26 Jan 2023

Study: FER1L5 protein essential for sperm to undergo acrosome reaction and male fertility

Fertilization is the union of two cells: an egg and a sperm. Before the egg and the sperm fuse, an event known as the "acrosome reaction" needs to occur in the sperm.

25 Jan 2023

Altered gut microbiome plays a major role in the progression of endometriosis in animal model

About 196 million women worldwide suffer from endometriosis, a condition that typically causes pelvic pain and infertility.

25 Jan 2023

Atomic-level computer model of the H1N1 virus reveals new vulnerabilities

According to the World Health Organization, each year there are an estimated 1 billion cases of influenza, between 3-5 million severe cases and up to 650,000 influenza-related respiratory deaths globally.

25 Jan 2023

Genetically increasing omega-3 fatty acid production improves glucose balance in obese mice

A new study from researchers at Laval University in Quebec, Canada, shows that genetically increasing omega-3 fatty acid production, without direct gut microbiota contact, improves the balance of insulin and glucagon (glucose balance) in obese mice.

25 Jan 2023

Dr. Yong joins Texas Tech Physicians of El Paso as an orthopedic surgeon

Taylor M. Yong, M.D., M.S., has joined Texas Tech University Health Sciences Center El Paso and Texas Tech Physicians of El Paso as an orthopedic surgeon who is fellowship trained in orthopedic trauma.

25 Jan 2023

Mount Sinai scientists earn $12 million to elucidate novel causes of food allergies and atopic dermatitis

Mount Sinai researchers have been awarded $12 million over five years by the National Institutes of Health to create a center to elucidate novel causes of, and contributing factors to, food allergies and atopic dermatitis.

25 Jan 2023

Injectable hydrogel composite loaded with stem cells shows success in treating perianal fistulas

In a new study using a rat model of Crohn's disease, a biodegradable hydrogel composite loaded with stem cells, developed by Johns Hopkins Medicine researchers, in a collaborative effort with the Whiting School of Engineering, has shown significant success in treating perianal fistulas (PAF) — one of the many complications of Crohn's disease.

25 Jan 2023

Lifetime ovulatory years positively associated with epithelial ovarian cancer

Francesmary Modugno, Ph.D., professor of obstetrics, gynecology and reproductive sciences at Magee-Womens Research Institute and UPMC Hillman Cancer Center

25 Jan 2023

Medical Science News

New collection of month-specific infant brain atlas captures fine details of the early developing brain

Persistent tumor mutation burden linked with therapeutic response to immunotherapy

PLK1-mTOR axis may be a promising therapeutic target for sepsis, study suggests

Using artificial human skin to block invasive growth in a skin cancer model

Researchers discover the impact of microRNA on inflammation in lupus

Study reveals the inevitability of Zika virus dumbbell-1 structure for viral pathogenesis

Prenatal MRI helps visualize SARS-CoV-2 infection-induced abnormalities in the placenta and fetuses

Researchers report on a genome-wide reconstruction of human microbes to develop personalized therapies

Study shows improved host health by modulating intestinal microbiota

Researchers develop a new multi-omics microsampling method for complete health profiling

Do individuals with acute attitudes toward science over-estimate their understanding of scientific matters?

New therapy-relevant marker may help identify ER+ breast cancer patients who may benefit from immunotherapies

Study: FER1L5 protein essential for sperm to undergo acrosome reaction and male fertility

Altered gut microbiome plays a major role in the progression of endometriosis in animal model

Atomic-level computer model of the H1N1 virus reveals new vulnerabilities

Genetically increasing omega-3 fatty acid production improves glucose balance in obese mice

Dr. Yong joins Texas Tech Physicians of El Paso as an orthopedic surgeon

Mount Sinai scientists earn $12 million to elucidate novel causes of food allergies and atopic dermatitis

Injectable hydrogel composite loaded with stem cells shows success in treating perianal fistulas

Lifetime ovulatory years positively associated with epithelial ovarian cancer

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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