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Study provides novel therapeutic targets for enhancing the antitumor immunity of γδ-T cells in diabetes

A research team at LKS Faculty of Medicine, The University of Hong Kong (HKUMed) discovered that high glucose impairs the antitumor activity of immune effector γδ-T cells, which contributes to the increased cancer risk in diabetes and that metabolic reprogramming by glucose control may improve the antitumor activity of γδ-T cells.

30 Nov 2022

Grape consumption protects against ultraviolet UV damage to the skin

A recent human study published this week in the scientific journal Antioxidants found that consuming grapes protected against ultraviolet (UV) damage to the skin. Study subjects showed increased resistance to sunburn after consuming 2 ¼ cups of grapes every day for two weeks.

30 Nov 2022

SARS-CoV-2 can cause hyperglycemia in cats

In a recent study published in The Journal of Infectious Diseases, researchers explored the association between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and hyperglycemia in cats.

30 Nov 2022

Specific genetic variant linked to early-onset childhood epilepsy discovered

Researchers at Children's Hospital of Philadelphia (CHOP) have discovered a specific genetic variant in SCN1A, the most common genetic epilepsy, that leads to an earlier onset of epilepsy, with clinical features distinct from other epilepsies.

30 Nov 2022

High concentrations of oxygen during anesthesia may increase risk of organ injury

Unnecessarily high concentrations of oxygen given to patients under general anesthesia may increase risk of injury to the kidneys, lungs and heart, according to a large Vanderbilt University Medical Center-led study published in The BMJ, the flagship journal of the British Medical Association.

30 Nov 2022

Detection of early-formed, antigen-specific clones in SARS-CoV-2-reactive B cells after longitudinal analysis

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the causal agent of the coronavirus disease 2019 (COVID-19) pandemic, has globally infected more than 639 million individuals and claimed over 6.6 million lives. Despite the rapid commencement of COVID-19 vaccination programs in most countries across the world, the virus has remained in circulation.

30 Nov 2022

Researchers modulate the activity of potential therapeutic target for triple-negative breast cancer

Less than 20% of diagnosed breast cancers are designated "triple-negative," lacking three types of receptors often found in other breast cancer types.

30 Nov 2022

Study reveals wasteosomes as markers of chronic glymphatic system insufficiency

A new study led by researchers from the University of Barcelona shows that wasteosomes - structures that act as containers for brain waste products - indicate a malfunction of the glymphatic system, a recently discovered system that is an important brain-cleaning mechanism.

30 Nov 2022

Study shows SARS-CoV-2 VOCs disseminated around the world according to different spatial source-sink dynamics

Researchers assessed the dispersion patterns of SARS-CoV-2 variants and their global expansion.

30 Nov 2022

Researchers receive $3 million-plus NIH grant to develop treatment for drug-resistant fungus

With a new $3 million-plus grant from the National Institutes of Health (NIH), Case Western Reserve University researchers are examining the next level of treatment for Candida auris (C.auris), a multidrug-resistant yeast that causes serious infection and, in some cases, death.

30 Nov 2022

Researchers identify two important factors involved in the formation and renewing of self-schema

At the end of a bad day, how do you feel about yourself? The answer could indicate not only how your self-perception formed, but also how it renews, according to experimental results from a research group in Japan.

30 Nov 2022

Research findings may offer a new potential therapeutic target for Alzheimer’s disease

A new study links a gene concentrated in the brain's cleanup cells, known as microglia, to the inflammation that has increasingly emerged as a key mechanism contributing to Alzheimer's disease.

30 Nov 2022

New drug candidates for male birth control may be on the horizon

For decades, researchers have been working on "male birth control" - and studies show there is a demand.

30 Nov 2022

Study on mpox epidemiology in New York during summer 2022

Researchers presented a summary of their experience of identifying, managing, and vaccinating monkeypox (MPX) virus (MPXV)-infected individuals in New York during the summer season of 2022.

30 Nov 2022

New evidence of mpox virus transmission before onset of symptoms

Researchers extensively followed-up high-risk contacts of clade IIb mpox (MPX) virus (MPXV)-infected patients to evaluate the risk of MPX after MPXV exposure and to characterize early MPXV infections.

30 Nov 2022

Plasma from vaccinated and COVID-19 convalescent subjects as passive immunotherapy against the new Omicron BQ.1.1, XBB, and BF.7 variants

Researchers systematically reviewed SARS-CoV-2 Omicron BQ.1.1 neutralization data from individual patient samples.

30 Nov 2022

Study suggests persistent immune activation and long COVID correlate independently with severe COVID-19

Researchers investigated whether severe COVID-19 patients exhibited inflammation and immune activation three months after hospitalization and explored the associations among COVID-19 severity, long COVID, and immune activation.

30 Nov 2022

Fragment crystallizable receptor-effector functions as a key correlate for pan-sarbecovirus vaccine development

Researchers elucidated pan-sarbecovirus immune protection mechanisms by utilizing a Venezuelan equine encephalitis virus-vectored vaccine panel that covered bat strains to human strains.

30 Nov 2022

Broadly cross-reactive antibodies that protect from SARS-CoV-2 variants are revealed by virus coldspot-driven discovery

A recent study identified neutralizing antibodies against conserved SARS-CoV-2 epitopes.

30 Nov 2022

The antibody resistance profile and viral receptor binding affinity of SARS-CoV-2 Omicron BQ.1, BQ.1.1, XBB, and XBB.1 subvariants

Researchers investigated the neutralizing antibody titers against the newly emergent BQ.1, BQ.1.1, XBB, and XBB.1 SARS-CoV-2 Omicron subvariants using sera from individuals with primary and booster COVID-19 vaccinations and previous SARS-CoV-2 infections.

30 Nov 2022

Medical Science News

Study provides novel therapeutic targets for enhancing the antitumor immunity of γδ-T cells in diabetes

Grape consumption protects against ultraviolet UV damage to the skin

SARS-CoV-2 can cause hyperglycemia in cats

Specific genetic variant linked to early-onset childhood epilepsy discovered

High concentrations of oxygen during anesthesia may increase risk of organ injury

Detection of early-formed, antigen-specific clones in SARS-CoV-2-reactive B cells after longitudinal analysis

Researchers modulate the activity of potential therapeutic target for triple-negative breast cancer

Study reveals wasteosomes as markers of chronic glymphatic system insufficiency

Study shows SARS-CoV-2 VOCs disseminated around the world according to different spatial source-sink dynamics

Researchers receive $3 million-plus NIH grant to develop treatment for drug-resistant fungus

Researchers identify two important factors involved in the formation and renewing of self-schema

Research findings may offer a new potential therapeutic target for Alzheimer’s disease

New drug candidates for male birth control may be on the horizon

Study on mpox epidemiology in New York during summer 2022

New evidence of mpox virus transmission before onset of symptoms

Plasma from vaccinated and COVID-19 convalescent subjects as passive immunotherapy against the new Omicron BQ.1.1, XBB, and BF.7 variants

Study suggests persistent immune activation and long COVID correlate independently with severe COVID-19

Fragment crystallizable receptor-effector functions as a key correlate for pan-sarbecovirus vaccine development

Broadly cross-reactive antibodies that protect from SARS-CoV-2 variants are revealed by virus coldspot-driven discovery

The antibody resistance profile and viral receptor binding affinity of SARS-CoV-2 Omicron BQ.1, BQ.1.1, XBB, and XBB.1 subvariants

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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