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Cleveland Clinic awarded $12 million NIH grant to define how cytokines regulate inflammation

Cleveland Clinic's Lerner Research Institute was awarded a five-year $12 million grant by the National Cancer Institute, part of the National Institutes of Health, to define how cytokines - proteins produced during immune response - regulate inflammation and interact with cells and molecules surrounding tumors.

28 Oct 2022

Study shows how Toxoplasma parasite successfully spreads in the body

The parasite Toxoplasma is carried by a large portion of the global human population. Now a study led by researchers at Stockholm University shows how this microscopic parasite so successfully spreads in the body, for example to the brain

28 Oct 2022

Novel nanotechnology triggers potent therapeutic anti-tumor immune responses against multiple cancers

A Ludwig Cancer Research study has developed a novel nanotechnology that triggers potent therapeutic anti-tumor immune responses and demonstrated its efficacy in mouse models of multiple cancers.

28 Oct 2022

Huntington's disease impairs autophagy in older patients

Huntington's disease, a fatal, inherited neurodegenerative condition, is caused by a genetic error present at birth, though its symptoms often don't begin until middle adulthood.

28 Oct 2022

Specific stem cell protein found to be involved in the recurrence of medulloblastoma

The malignant brain tumor type medulloblastoma can become resistant to therapy which can cause relapse. Researchers at Uppsala University have discovered a certain protein that makes tumor cells resting and insensitive to radiation treatment.

28 Oct 2022

Researchers discover how hydroquinine inhibits major drug-resistant bacteria

Researchers say hydroquinine could be an effective weapon against a germ that can cause serious infections in humans, mostly hospital patients

28 Oct 2022

Brain Canada Foundation funds future leaders in Canadian brain research

Twenty early-career researchers from across Canada will receive $100,000 each in funding for innovative projects to better understand the brain, through one of Brain Canada's flagship programs Future Leaders in Canadian Brain Research.

28 Oct 2022

The impact of seasonal coronavirus immunity on susceptibility to SARS-CoV-2 infection and COVID-19 vaccination

Researchers investigated whether immunity against seasonal human coronavirus spike proteins of HKU1, OC43, NL63, or 229E could protect against SARS-CoV-2 in vitro.

28 Oct 2022

Booster vaccination offered additional protection to residents and staff of California state prisons against SARS-CoV-2 Omicron

Researchers evaluated to what extent prior infection and vaccination protected the residents and staff of the United States California state prison system from breakthrough infection by SARS-CoV-2 Omicron sub-variant B.1.1.529.

28 Oct 2022

Study refutes the nicotinic hypothesis of SARS-CoV-2 infection mechanism

A new study confirmed that the SARS-CoV-2 spike protein does not bind to human AChR’s orthosteric sites, nor does it compete with ACh, choline, or nicotine.

28 Oct 2022

What are the contemporary hazards of cigarette smoking and benefits of quitting smoking by race, ethnicity, and sex among US adults?

Researchers quantified the association between cigarette smoking and all-cause and cause-specific deaths by sex, ethnicity, and race.

28 Oct 2022

E-cigarette use alters respiration but does not impair lung function, according to new findings

A new study indicated that although vaping increases airway resistance, it does not impact lung function.

28 Oct 2022

The epigenetic alterations of monocytes in severe COVID-19

Researchers performed DNA methylation analysis on monocytes in the peripheral blood samples obtained from severe COVID-19 patients.

28 Oct 2022

Association of COVID-19 severity with nasopharyngeal fungal colonization and interleukin-17 induction

Researchers evaluated the concurrent colonization of fungi in the nasopharynx of severe COVID-19 patients.

28 Oct 2022

The dynamics of COVID-19 conspiracist ideation

Researchers studied the dynamics of COVID-19 conspiracist ideation—a general tendency to believe in conspiracy theories.

28 Oct 2022

Scientists computationally restore the potency of an antibody against SARS-CoV-2 Omicron subvariants

A team of researchers from the United States computationally modified the COV2-2130 monoclonal antibody to restore its neutralizing ability against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron subvariants, while retaining efficacy against the Delta and wild-type strains.

27 Oct 2022

Commensal gut microbes from IBD patients produce genotoxic metabolites

Functional screening of human gut microbiota reveals a family of small molecule genotoxins called indolimines in patients with inflammatory bowel disease (IBD), according to a new study.

27 Oct 2022

Combination of multi-specificity and antibody avidity enhances protection against SARS-CoV-2

In a recent study posted to the bioRxiv* preprint server, an international team of researchers leveraged the human light chain apoferritin protomer-derived MULTI-specific, multi-Affinity antibody (Multabody, MB) platform for the generation of broad and potent SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2)-neutralizing antibodies (Abs).

27 Oct 2022

An unprecedented list of health-threatening fungi released by the WHO

The WHO fungal priority pathogens list ranks pathogens that pose a serious risk of morbidity and mortality in humans.

27 Oct 2022

Study sheds light on why some patients respond better than others to immunotherapy

Immunotherapy, a biotherapy that boosts the ability of the immune system to recognize and attack mutant tumor cells, has transformed the treatment landscape for patients battling cancer, which emerges from the progressive accumulation of DNA mutations.

27 Oct 2022

Medical Science News

Cleveland Clinic awarded $12 million NIH grant to define how cytokines regulate inflammation

Study shows how Toxoplasma parasite successfully spreads in the body

Novel nanotechnology triggers potent therapeutic anti-tumor immune responses against multiple cancers

Huntington's disease impairs autophagy in older patients

Specific stem cell protein found to be involved in the recurrence of medulloblastoma

Researchers discover how hydroquinine inhibits major drug-resistant bacteria

Brain Canada Foundation funds future leaders in Canadian brain research

The impact of seasonal coronavirus immunity on susceptibility to SARS-CoV-2 infection and COVID-19 vaccination

Booster vaccination offered additional protection to residents and staff of California state prisons against SARS-CoV-2 Omicron

Study refutes the nicotinic hypothesis of SARS-CoV-2 infection mechanism

What are the contemporary hazards of cigarette smoking and benefits of quitting smoking by race, ethnicity, and sex among US adults?

E-cigarette use alters respiration but does not impair lung function, according to new findings

The epigenetic alterations of monocytes in severe COVID-19

Association of COVID-19 severity with nasopharyngeal fungal colonization and interleukin-17 induction

The dynamics of COVID-19 conspiracist ideation

Scientists computationally restore the potency of an antibody against SARS-CoV-2 Omicron subvariants

Commensal gut microbes from IBD patients produce genotoxic metabolites

Combination of multi-specificity and antibody avidity enhances protection against SARS-CoV-2

An unprecedented list of health-threatening fungi released by the WHO

Study sheds light on why some patients respond better than others to immunotherapy

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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