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Model predicts effectiveness of COVID-19 vaccines against circulating SARS-CoV-2 variants

In a recent study published in the journal Nature Medicine, researchers assessed the coronavirus disease 2019 (COVID-19) vaccine effectiveness (VE) against symptomatic infections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) and variants of interest (VOIs) by genetic mismatch/distance (GD) analysis.

20 Jun 2022

Gut microbiome acts on the brain to control appetite

Hypothalamic GABAergic neurons recognize microbial muropeptides through the cytosolic receptor NOD2, which regulates food intake and body temperature.

19 Jun 2022

Combating monkeypox during COVID-19

Scientists describe the global prevalence and significance of the current monkeypox virus outbreak.

19 Jun 2022

Multifunctional nanoparticle system may be a promising therapeutic way for breast cancer therapy

In this new article publication from Acta Pharmaceutica Sinica B, authors Yun Yang, Danrong Hu, Yi Lu, Bingyang Chu, Xinlong He, Yu Chen, Yao Xiao, Chengli Yang, Kai Zhou, Liping Yuan and Zhiyong Qian from Sichuan University, Chengdu discuss tumor-targeted/reduction-triggered composite multifunctional nanoparticles for breast cancer chemo-photothermal combinational therapy.

18 Jun 2022

Machine learning predictive model for screening of LNP-based mRNA vaccines

In this new article publication from Acta Pharmaceutica Sinica B, authors Wei Wang, Shuo Feng, Zhuyifan Ye, Hanlu Gao, Jinzhong Lin and Defang Ouyang from University of Macau, Macau, China and Fudan University, Shanghai, China discuss the prediction of lipid nanoparticles for mRNA vaccines by machine learning algorithms.

18 Jun 2022

Study points to a new direction for the development of NAMPT-targeted cancer therapies

In this new article publication from Acta Pharmaceutica Sinica B, authors Ying Wu, Congying Pu, Yixian Fu, Guoqiang Dong, Min Huang and Chunquan Sheng from Second Military Medical University, Shanghai, China and University of Chinese Academy of Sciences, Shanghai, China discuss how NAMPT-targeting PROTAC promotes antitumor immunity via suppressing myeloid-derived suppressor cell expansion.

18 Jun 2022

Traumatic brain injury changes the connections between nerve cells across the entire brain

Scientists from the University of California, Irvine have discovered that an injury to one part of the brain changes the connections between nerve cells across the entire brain.

17 Jun 2022

Eyes may be able to signal ASD and ADHD

It's often said that 'the eyes tell it all', but no matter what their outward expression, the eyes may also be able to signal neurodevelopmental disorders such as ASD and ADHD according to new research from Flinders University and the University of South Australia.

17 Jun 2022

Nanoparticles may be the next-generation solution for teeth whitening

Researchers reviewed nanoparticles (NPs) as next-generation whitening agents for teeth.

17 Jun 2022

New discovery could lead to the development of therapeutic approaches for retinitis pigmentosa

Retinitis pigmentosa, a degenerative genetic disease of the eye, is characterized by progressive vision loss, usually leading to blindness.

17 Jun 2022

Effectiveness of previous COVID-19 and vaccination against SARS-CoV-2 Omicron infection

Researchers studied the effects of prior immunity on symptomatic infection by SARS-CoV-2 Omicron.

17 Jun 2022

Clinical risk and protective factors for the presence and persistence of abdominal pain-related disorders of gut-brain interaction

The current study carries forward what is known about the risk of AP-DGBI conferred by various factors such as sex, infectious gastroenteritis, trauma, abuse, stress, psychological factors, somatic symptoms, family history, smoking, and drug abuse.

17 Jun 2022

Assessing neurological symptoms present in long COVID patients

Researchers assessed the symptoms of neurological post-acute sequelae of SARS-CoV-2 infection (neuro-PASC) among patients with and without neurologic disorders.

17 Jun 2022

Study explains the structural basis of higher ACE2 binding affinity of Omicron sub-variants

A team of scientists from China has recently deciphered the structural basis of comparatively higher binding affinity of two Omicron sub-variants, namely B.1.1 and B.2, for human angiotensin-converting enzyme 2 (ACE2).

17 Jun 2022

SARS-CoV-2 variant-specific polymerase chain reaction assay for SARS-CoV-2 genomic surveillance

Researchers reported on the misclassification of the SARS-CoV-2 Omicron BA.1 subvariant as Omicron BA.2 subvariant in an automated variant-specific polymerase chain reaction analysis.

17 Jun 2022

Researchers investigate COVID fog and chemokine C–C motif ligand 11

Researchers assessed the characteristics of the brain fog reported by some COVID-19 patients.

17 Jun 2022

Scientists explore effectiveness of neutralizing antibodies against SARS-CoV-2 Omicron variant

Researchers assessed the impact of SARS-CoV-2-neutralizing antibodies on the SARS-CoV-2 Omicron variant.

17 Jun 2022

Conceptual framework to examine the patterns of copy number alterations in human cancer

A new study published in Nature presented a conceptual framework to examine the patterns of copy number alterations in human cancer.

17 Jun 2022

Demonstrating varying pathogenicity and tropism of SARS-CoV-2 variants in a feline model

In a recent study posted to the bioRxiv* pre-print server, researchers at Cornell University College of Veterinary Medicine and the University of Illinois Urbana-Champaign compared the infection dynamics, pathogenicity, and tissue tropism of multiple severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants in adult cats.

17 Jun 2022

GPR183 gene a novel drug target for severe COVID-19

In a recent study posted to the bioRxiv* pre-print server, researchers provide the first preclinical evidence of the usefulness of antagonists of G-protein coupled receptor 183 (GPR183), also known as Epstein-Barr virus-induced gene 2 (EBI2), in reducing coronavirus disease 2019 (COVID-19) severity.

17 Jun 2022

Medical Science News

Model predicts effectiveness of COVID-19 vaccines against circulating SARS-CoV-2 variants

Gut microbiome acts on the brain to control appetite

Combating monkeypox during COVID-19

Multifunctional nanoparticle system may be a promising therapeutic way for breast cancer therapy

Machine learning predictive model for screening of LNP-based mRNA vaccines

Study points to a new direction for the development of NAMPT-targeted cancer therapies

Traumatic brain injury changes the connections between nerve cells across the entire brain

Eyes may be able to signal ASD and ADHD

Nanoparticles may be the next-generation solution for teeth whitening

New discovery could lead to the development of therapeutic approaches for retinitis pigmentosa

Effectiveness of previous COVID-19 and vaccination against SARS-CoV-2 Omicron infection

Clinical risk and protective factors for the presence and persistence of abdominal pain-related disorders of gut-brain interaction

Assessing neurological symptoms present in long COVID patients

Study explains the structural basis of higher ACE2 binding affinity of Omicron sub-variants

SARS-CoV-2 variant-specific polymerase chain reaction assay for SARS-CoV-2 genomic surveillance

Researchers investigate COVID fog and chemokine C–C motif ligand 11

Scientists explore effectiveness of neutralizing antibodies against SARS-CoV-2 Omicron variant

Conceptual framework to examine the patterns of copy number alterations in human cancer

Demonstrating varying pathogenicity and tropism of SARS-CoV-2 variants in a feline model

GPR183 gene a novel drug target for severe COVID-19

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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