Molecular & Structural Biology

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New technology can increase the quality of stem cells used in regenerative medicine

Stem cells have been holding great promise for regenerative medicine for years. In the last decade, several studies have shown that this type of cell, which in Spanish is called "mother cell" because of its ability to give rise to a variety of different cell types, can be applied in regenerative medicine for diseases such as muscular and nervous system disorders, among others.

2 Jul 2020

Developing Vaccines and Therapeutics by Exploiting Structure in Spherical Nucleic Acids

An interview discussing the use of spherical nucleic acids (SNAs) and what they show about the importance of structure in pharmaceutical development.

From Pittcon 2 Jul 2020

CityU develops CRISPR-assisted method to identify RNA-binding proteins in living cells

While scientists still don't fully understand the diverse nature of RNA molecules, it is believed that the proteins binding to them, called RNA-binding proteins, are associated with many disease formation.

1 Jul 2020

Researchers discover a protein that protects B cells from stress-induced cell death

Whenever a germ gets into the human body, the immune system usually responds immediately to fight off the enemy attacker. One of our defense system's most important strategies involves B lymphocytes, also known as B cells, which produce antibodies that target and neutralize pathogens.

1 Jul 2020

Research shows how a protein's small change leads to big trouble for cells

In molecular biology, chaperones are a class of proteins that help regulate how other proteins fold. Folding is an important step in the manufacturing process for proteins. When they don't fold the way they're supposed to, it can lead to the development of diseases such as cancer.

30 Jun 2020

A data-rich atlas of the developing human brain

For the nascent brain of a human embryo to develop into the complex organ that controls human consciousness, a finely tuned sequence of genetic events has to take place; hundreds of genes are activated and deactivated in a precise symphony.

30 Jun 2020

Study uncovers algorithms and neural circuit mechanisms of escape responses

Ordered and variable animal behaviours emerge to explore and adapt to the environment. They are generally considered as the combination of a series of stereotyped motor primitives. However, how the nervous system shapes the dynamics of motor sequences remains to be solved.

29 Jun 2020

Scientists discover osmotic stress as stimulator of cellular waste disposal

Cellular waste disposal, where autophagy and lysosomes interact, performs elementary functions, such as degrading damaged protein molecules, which impair cellular function, and reintroducing the resulting building blocks such as amino acids into the metabolic system.

29 Jun 2020

Biophysicists propose a simple way to observe heart tissue

Biophysicists from the Moscow Institute of Physics and Technology and their colleagues have proposed a simple way to observe the heart tissue.

29 Jun 2020

Researchers provide mechanistic insight into protein co-aggregation in Alzheimer's disease

A research team lead by Ludmilla Morozova Roche at Umeå University, Sweden, has provided the mechanistic insight into protein co-aggregation in Alzheimer's disease.

26 Jun 2020

New steroid compounds from deep-water starfish show anticancer activity

Russian scientists from Far Eastern Federal University, G. B. Elyakov Pacific Institute of Bioorganic Chemistry, and A.V. Zhirmunsky National Scientific Center for Marine Biology have discovered four new steroid substances which target cells of human breast cancer, and colorectal carcinoma.

26 Jun 2020

Researchers identify new protein complex that regulates chromosome separation

Researchers from the University of Tsukuba have identified a novel protein complex that regulates Aurora B localization to ensure that chromosomes are correctly separated during cell division

26 Jun 2020

Researchers identify new molecules to study specific glial cells integral to synapses

While the brain is composed of two types of cells, glia tend to receive far less attention for their importance in brain function and disease than the more celebrated neurons.

26 Jun 2020

Simplified artificial cell brings to light the dynamics of cellular symmetry

Symmetry and asymmetry are fundamental properties of nature. Seen from above, butterflies have left-right symmetry, while male fiddler crabs show dramatic asymmetry.

25 Jun 2020

Single-cell sequencing method reveals possible evolutionary trajectories of cancer cells

The ability to sequence the genome of a tumor has revolutionized cancer treatment over the last 15 years by identifying drivers of cancer at the molecular level.

25 Jun 2020

Tiny protein in mitochondria has a big impact on health and longevity, study shows

A new study led by researchers at the USC Leonard Davis School of Gerontology is the first to demonstrate that a tiny protein has a big impact on health and longevity in both animals and humans.

24 Jun 2020

Researchers develop less invasive genetic tools to understand cellular activity

Graduate student Ubadah Sabbagh placed a cold glass slide on the microscope. It was getting late and the lab was quiet.

24 Jun 2020

Study highlights the challenges involved in designing universal flu vaccine

Some common strains of influenza have the potential to mutate to evade broad-acting antibodies that could be elicited by a universal flu vaccine, according to a study led by scientists at Scripps Research.

23 Jun 2020

Scientists create hollow, spherical sacks using protein and RNA

Using protein and RNA, scientists have created hollow, spherical sacks known as vesicles.

23 Jun 2020

Researchers develop method to assess mitochondrial respiration in frozen tissues

Scientists led by Dr. Orian Shirihai, director of the metabolism theme at the David Geffen School of Medicine at UCLA, have developed a method for restoring oxygen-consumption activity to previously frozen mitochondria samples, even years after they have been collected.

23 Jun 2020

Molecular & Structural Biology

New technology can increase the quality of stem cells used in regenerative medicine

Developing Vaccines and Therapeutics by Exploiting Structure in Spherical Nucleic Acids

CityU develops CRISPR-assisted method to identify RNA-binding proteins in living cells

Researchers discover a protein that protects B cells from stress-induced cell death

Research shows how a protein's small change leads to big trouble for cells

A data-rich atlas of the developing human brain

Study uncovers algorithms and neural circuit mechanisms of escape responses

Scientists discover osmotic stress as stimulator of cellular waste disposal

Biophysicists propose a simple way to observe heart tissue

Researchers provide mechanistic insight into protein co-aggregation in Alzheimer's disease

New steroid compounds from deep-water starfish show anticancer activity

Researchers identify new protein complex that regulates chromosome separation

Researchers identify new molecules to study specific glial cells integral to synapses

Simplified artificial cell brings to light the dynamics of cellular symmetry

Single-cell sequencing method reveals possible evolutionary trajectories of cancer cells

Tiny protein in mitochondria has a big impact on health and longevity, study shows

Researchers develop less invasive genetic tools to understand cellular activity

Study highlights the challenges involved in designing universal flu vaccine

Scientists create hollow, spherical sacks using protein and RNA

Researchers develop method to assess mitochondrial respiration in frozen tissues

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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