Molecular & Structural Biology

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E. coli eavesdrops on neighboring bacteria to stabilize gut diversity

The stability of the human gut microbiome relies on interactions between different bacterial species. However, the specific molecular mechanisms of these interactions, particularly among non-dominant species, remain largely unexplored.

14 Oct 2026

Scientists find strange bacterial immune system that works backward

Researchers at Gladstone Institutes have uncovered an extraordinarily unusual bacterial immune system that operates in reverse of known defenses.

13 Oct 2026

Three-dimensional genome structure shapes complex traits in cephalopods

Octopuses, squid and cuttlefish, collectively known as coleoid cephalopods, have evolved exceptionally large and elaborately structured nervous systems capable of complex behaviours such as problem-solving and rapid camouflage.

12 Oct 2026

Amphista Therapeutics announces first patient dosed in AMX-883 Phase 1 clinical trial for acute myeloid leukemia

Amphista Therapeutics Limited ('Amphista'), a leader in the discovery and development of non-cereblon / VHL targeted protein degradation (TPD) medicines, today announced dosing of the first patient in a Phase 1 trial for its lead candidate, AMX-883. Initiated following authorization from the U.S. Food and Drug Administration in June 2026, the BRAMLIE trial will investigate the safety, pharmacokinetics, and preliminary efficacy of AMX-883 monotherapy in participants with AML and high-risk MDS.

From Amphista Therapeutics 12 Oct 2026

Real time molecular movie unlocks secrets of penicillin biosynthesis

Researchers from the University of Oxford and international collaborators have revealed previously unseen rapid chemical stages in the formation of β-lactam antibiotics like penicillin, offering insights that can support future antibiotic development.

9 Oct 2026

Bio-Techne expands global GMP manufacturing network with new Bristol facility to advance scalable cell therapy development

Bio-Techne Corporation, a global provider of life science tools, reagents and diagnostic products, today announced the opening of a new manufacturing facility for Good Manufacturing Practice (GMP) grade small molecules in Bristol, United Kingdom, further expanding the company's global capabilities to support the rapidly growing cell therapy market.

From Bio-Techne 8 Oct 2026

Study reveals link between mtDNA copy number and cancer severity

Mitochondria are small organelles within cells that play a central role in vital cellular processes, especially energy production.

7 Oct 2026

ESTEVE CDMO expands U.S. capacity with additional $17.5 million investment in Morton Grove

ESTEVE CDMO, a global pure-play CDMO specializing in the development and manufacture of small-molecule APIs and pharmaceutical intermediates, has approved an additional $17.5 million capacity expansion and containment capabilities at its Morton Grove, Illinois facility, bringing total announced investment at the site to $33 million.

From ESTEVE CDMO 5 Oct 2026

New project explores mitochondrial evolution across diverse life forms

A research consortium has generated the broadest look yet at the proteins that make up mitochondria, capturing the organelle's diversity across multiple branches on the tree of complex life.

1 Oct 2026

Simulations reveal how changing enzyme shapes affect molecular recognition

Enzymes are often described as molecular machines that recognize and process specific molecules. However, they are not rigid structures. Their shapes can change, and these changes can affect how molecules enter, interact with, and remain within their active sites.

29 Sep 2026

New study explains how TMEM63B protein regulates cell membranes

An autoinhibitory domain in the C-terminal tail of the TMEM63B, a mechanosensitive lipid scramblase, helps maintain its inactive state under resting conditions, report researchers from Institute of Science Tokyo.

29 Sep 2026

Tapping the power of cryo-ET to visualize how molecular machines interact inside cells

Scientists have often thought of cells as small bustling cities with parts that resemble factories, power grids, and shipping systems.

25 Sep 2026

Protein modification network plays vital role in cancer development

A review published in Genes & Diseases highlights the complex interplay between protein arginine methylation and ubiquitination, two forms of protein modification that can profoundly influence cancer development, progression and treatment response.

24 Sep 2026

NSF awards $19 million to build 3D biological observatory for revealing life's smallest structures

How does learning change the wiring of your brain? How does a shark's eye make sense of its underwater world? How does a single-celled parasite cross the barrier that protects the brain? What might neurodegeneration look like at ultra-magnified scale?

24 Sep 2026

Structural insights into synchronous calcium channel gating in muscle cells

Using cryo-electron microscopy, researchers at the Max Delbrück Center have revealed how muscle cell calcium channels open synchronously.

24 Sep 2026

Engineered nanoparticles sensitize gliomas to radiotherapy

Gliomas are a major cause of cancer-related deaths in younger adults.

24 Sep 2026

Scientists map a giant parasite machine to fight tropical diseases

A study conducted between the University of Liège and Rockefeller University reveals, with near-atomic precision, the three-dimensional structure and function of a gigantic molecular machine essential to the survival of trypanosomatid parasites, which cause serious diseases in humans, animals and plants.

23 Sep 2026

Submicron IR for pharmaceutical research, development, and quality

The pharmaceutical and biopharmaceutical industries increasingly require rapid, accurate, and high-resolution analytical tools to characterize complex materials, ensure product quality, and accelerate innovation.

From Photothermal Spectroscopy Corp 22 Sep 2026

Cohesin protein protects genetic information during cell division

Cell division, a process fundamental to life, still holds surprises. Researchers from the University of Zurich and the Spanish National Cancer Research Centre (CNIO) have discovered a key mechanism that allows cells to protect genetic information as they divide.

21 Sep 2026

Study reveals how CaMKIIα proteins organize during memory formation

Researchers at the Nano Life Science Institute (WPI-NanoLSI) at Kanazawa University, Kyoto University, SOKENDAI, and the National Institute for Physiological Sciences have revealed how CaMKIIα-a key brain protein involved in learning and memory-organizes itself into chain-like structures.

20 Sep 2026