Molecular & Structural Biology

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Study unravels FOXO1's influence on blood vessel development

The human vascular system, a complex network of blood vessels, plays an essential role in maintaining health. Understanding the molecular mechanisms underlying vascular development is important for tackling age-related disorders.

9 Mar 2024

Study reveals key mechanism of PD-1 function

Insights into the workings of an immune cell surface receptor, called PD-1, reveal how treatments that restrict its action can potentially be strengthened to improve their anticancer effect, a new study shows.

9 Mar 2024

Kobe University study identifies FAM81A as key player for synaptic function

A protein that appears in postsynaptic protein agglomerations has been found to be crucial to their formation.

7 Mar 2024

Key brain cells linked to repetitive behaviors in psychiatric diseases

Crym-expressing astrocytes in the striatum have been identified as key regulators of behaviors often seen in neuropsychiatric diseases, opening up new avenues for targeted therapies.

6 Mar 2024

RAD51 protein identified as a key player in preventing DNA re-replication

Every time a cell divides, its DNA is duplicated so that the two daughter cells have the same genetic material as their parent.

4 Mar 2024

How live music directly stimulates the affective brain, emotionally engaging listeners in real time

Researchers explore how live and recorded music stimulates the brain.

4 Mar 2024

Structural study identifies target for broad-spectrum antivirals against herpesviruses

Human herpesviruses comprise the alpha, beta, and gamma subfamilies and are a widely prevalent group of DNA-enveloped viruses, capable of establishing lifelong latent infections in humans and causing various diseases.

26 Feb 2024

AI tool helps develop the most complete map of the bacterial essential interactome

Universitat Autonoma de Barcelona (UAB) researchers have produced the most complete map of the bacterial essential interactome, i.e. how proteins combine and interact to perform functions essential for their survival.

23 Feb 2024

Advancing gene regulatory network inference with causal discovery and graph neural networks

Gene regulatory networks (GRNs) depict the regulatory mechanisms of genes within cellular systems as a network, offering vital insights for understanding cell processes and molecular interactions that determine cellular phenotypes.

23 Feb 2024

Digital DNA melting analysis can be a faster and more reliable tool for pathogen detection

A new analysis method can detect pathogens in blood samples faster and more accurately than blood cultures, which are the current state of the art for infection diagnosis.

21 Feb 2024

Molecular glue could pave the way for new generation of drugs

A breakthrough class of molecular glue identified at the University of Dundee could pave the way for a new generation of drugs to target cancers and neurodegenerative diseases.

21 Feb 2024

IκBζ protein holds potential for treating autoimmune conditions

Our immune system is remarkably powerful. It quickly assembles teams of cells to eliminate threats inside our bodies.

21 Feb 2024

Discovery of novel enzyme family holds potential for antibiotic development

Researchers at Umeå University in Sweden, led by Professor Felipe Cava, have identified a new family of enzymes that creates a unique type of cross-linking between the building blocks of bacterial cell walls.

19 Feb 2024

AI revolutionizes protein function prediction with "DeepGO-SE"

Researchers developed "DeepGO-SE," a novel AI method for predicting protein functions from sequences, significantly outperforming traditional models by incorporating gene ontology and protein-protein interactions.

15 Feb 2024

GV1001 exerts anti-aging effects in triple transgenic Alzheimer's mice

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 3, entitled, "GV1001 reduces neurodegeneration and prolongs lifespan in 3xTg-AD mouse model through anti-aging effects."

15 Feb 2024

Breaking through new research barriers with iPSC technology

In this interview, we speak to Keith Olson and Coby Carlson from Fujifilm Cellular Dynamics about their iPSC technology.

From FUJIFILM Cellular Dynamics 15 Feb 2024

Researchers discover new mechanism of action between the nutrient adaptation of intestinal stem cells and aging

Researchers used an organ-wide approach to quantitatively analyze cell number, size, and identity regulation upon nutrient-induced tissue adaptation of the Drosophila midgut.

15 Feb 2024

COVID-19's lasting impact on smell and brain health unveiled

Study reviews the impact of COVID-19 on olfactory dysfunction and its link to neurocognitive disorders, highlighting MRI findings and potential treatments for smell loss.

12 Feb 2024

Genetics of estrogen production linked to endometrial cancer risk in postmenopausal women

A study in eBioMedicine identifies genetic factors regulating blood estrone levels in postmenopausal women, linking specific genetic loci to an increased risk of endometrial cancer, highlighting the role of non-ovarian estrogen production in cancer development.

11 Feb 2024

Decoding the differences between two vital RNA transport complexes

Genetic expression, often leading to protein synthesis, requires a complex coordination of molecular machinery across several stages.

8 Feb 2024

Molecular & Structural Biology

Study unravels FOXO1's influence on blood vessel development

Study reveals key mechanism of PD-1 function

Kobe University study identifies FAM81A as key player for synaptic function

Key brain cells linked to repetitive behaviors in psychiatric diseases

RAD51 protein identified as a key player in preventing DNA re-replication

How live music directly stimulates the affective brain, emotionally engaging listeners in real time

Structural study identifies target for broad-spectrum antivirals against herpesviruses

AI tool helps develop the most complete map of the bacterial essential interactome

Advancing gene regulatory network inference with causal discovery and graph neural networks

Digital DNA melting analysis can be a faster and more reliable tool for pathogen detection

Molecular glue could pave the way for new generation of drugs

IκBζ protein holds potential for treating autoimmune conditions

Discovery of novel enzyme family holds potential for antibiotic development

AI revolutionizes protein function prediction with "DeepGO-SE"

GV1001 exerts anti-aging effects in triple transgenic Alzheimer's mice

Breaking through new research barriers with iPSC technology

Researchers discover new mechanism of action between the nutrient adaptation of intestinal stem cells and aging

COVID-19's lasting impact on smell and brain health unveiled

Genetics of estrogen production linked to endometrial cancer risk in postmenopausal women

Decoding the differences between two vital RNA transport complexes

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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