Molecular & Structural Biology

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Nicotine beliefs elicit dose-response reactions in human brains

Researchers investigate whether nicotine-related beliefs may influence brain processes in a dose-dependent manner similar to pharmaceutical effects.

10 Jan 2024

New peptide library paves the way for targeting elusive cancer factor MYC

Researchers developed a second-generation NTB bicyclic peptide library, identifying NT-B2R, a peptide that effectively targets MYC, a key factor in most human cancers, demonstrating its potential in inhibiting MYC transcription activities and cancer cell proliferation.

8 Jan 2024

Scientists unveil the hidden respiratory mechanisms of gut bacteria

Study explores the use of respiratory electron acceptors by diverse gut bacteria, revealing a novel type of anaerobic respiration linked to the gut metabolome and microbial energy metabolism.

8 Jan 2024

Disease-causing bacteria use molecular "barcode" to distinguish between beneficial and toxic molecules

Researchers at McMaster University have discovered a molecular "barcode" system used by disease-causing bacteria to distinguish between beneficial and toxic molecules.

8 Jan 2024

Novel approach to de novo protein design enables creation of diverse functional structures

A team of researchers has developed an innovative method to design complicated all-α proteins, characterized by their non-uniformly arranged α-helices as seen in hemoglobin.

4 Jan 2024

Retinotopic coding bridges perception and memory in the brain, study finds

Study reveals that retinotopic coding in the brain cortex plays a crucial role in processing visual information from the retina, influencing both perception and memory systems.

3 Jan 2024

Cytonemes: The "express subways" of the developing nervous system

St. Jude Children's Research Hospital scientists found that cytonemes (thin, long, hair-like projections on cells) are important during neural development.

3 Jan 2024

Small molecule-switchable RNA platform enables control of therapeutic protein expression

Just like a doctor adjusts the dose of a medication to the patient's needs, the expression of therapeutic genes, those modified in a person to treat or cure a disease via gene therapy, also needs to be maintained within a therapeutic window.

2 Jan 2024

How immune cells shape our earliest breaths

Study profiles the development of immune cells in human lungs during embryonic and fetal stages, revealing their influence on epithelial cell fate and lung development.

1 Jan 2024

Catenane magic: Boosting protein stability and resilience with interlocking rings

This study is led by Prof. Wen-Bin Zhang (College of Chemistry and Molecular Engineering, Peking University & Beijing Academy of Artificial Intelligence) and Dr. Jing Fang (College of Chemistry and Molecular Engineering, Peking University).

29 Dec 2023

Cadmium linked to DNA damage and morphological changes caused by particulate matter

Particulate matter causes health problems for those who inhale the fine droplets and particles, but the chemical composition of the mixture matters-;and can vary widely across space and time.

28 Dec 2023

Neutrophils: Unraveling their multifaceted roles in inflammatory bowel disease and gut microbiota interactions

Research delves into the complex roles of neutrophils in inflammatory bowel disease (IBD), exploring their diverse functions and interactions with the gut microbiota and emphasizing the need for targeted therapies based on these insights.

27 Dec 2023

Research reveals how "forever chemicals" damage DNA at the molecular level

Recent research published in the journal Eco-Environment & Health (Volume 2, 2023) reveals groundbreaking insights into how typical PFAAs accelerate the degradation of DNA.

26 Dec 2023

Fox urine compound effectively repels flies through multisensory activation

Crop damage in agriculture and the transmission of vector-borne diseases by insect pests have become worldwide threat nowadays.

25 Dec 2023

St. Jude researchers crack the code of the β2-adrenergic receptor

Through an international collaboration, scientists at St. Jude Children's Research Hospital leveraged data science, pharmacology and structural information to conduct an atomic-level investigation into how each amino acid in the receptor that binds adrenaline contributes to receptor activity in the presence of this natural ligand.

22 Dec 2023

Molecular & Structural Biology

Nicotine beliefs elicit dose-response reactions in human brains

New peptide library paves the way for targeting elusive cancer factor MYC

Scientists unveil the hidden respiratory mechanisms of gut bacteria

Disease-causing bacteria use molecular "barcode" to distinguish between beneficial and toxic molecules

Novel approach to de novo protein design enables creation of diverse functional structures

Retinotopic coding bridges perception and memory in the brain, study finds

Cytonemes: The "express subways" of the developing nervous system

Small molecule-switchable RNA platform enables control of therapeutic protein expression

How immune cells shape our earliest breaths

Catenane magic: Boosting protein stability and resilience with interlocking rings

Cadmium linked to DNA damage and morphological changes caused by particulate matter

Neutrophils: Unraveling their multifaceted roles in inflammatory bowel disease and gut microbiota interactions

Research reveals how "forever chemicals" damage DNA at the molecular level

Fox urine compound effectively repels flies through multisensory activation

St. Jude researchers crack the code of the β2-adrenergic receptor

Shedding new light on the hidden organization of the cytoplasm

St. Jude researchers reveal structure of Parkinson's-linked proteins

Clearing the cellular clutter: New insights into how our cells stay healthy

TMDU researchers develop novel method to identify protein-protein binding interfaces

Study reveals cytoglobin's pivotal role in cilia movement and organ positioning during development

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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