Molecular & Structural Biology

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Researchers develop molecular beacon to find hypoxic spots in real time

Areas of hypoxia, or low oxygen in tissue, are hallmarks of fast-growing cancers and of blockages or narrowing in blood vessels, such as stroke or peripheral artery disease. University of Illinois researchers have developed a way to find hypoxic spots noninvasively in real time.

8 Dec 2017

Researchers establish function of long RNA strands in skin development and disease

Researchers have found out how long pieces of RNA called “long non-coding RNAs” (LncRNAs) work in skin cells to modulate connective tissue proteins such as collagen, potentially laying the foundations for new skin repair therapies.

7 Dec 2017

Biological Applications of AFM

An interview with Samuel Lesko, European Applications Manager, Bruker Nano Surfaces conducted by April Cashin-Garbutt, MA (Cantab).

From Bruker Nano Surfaces and Metrology 5 Dec 2017

Overcoming Challenges of Assays of Complex Cellular Models with Real-Time Live-Cell Analysis

There's a continued drive towards making in vitro assays ever more translational towards in vivo models and ultimately the clinic. This ties in with the resurgence of phenotypic screening and is a response to the perceived poor translation of the traditional simple cell-based assays, often developed to study just single protein targets.

From Sartorius 5 Dec 2017

Malvern Panalytical Announce Efforts Towards a Platform For Protein Aggregation Profiling

Malvern Panalytical announces the launch of a collaborative project which aims to support the development of existing and next generation biopharmaceutical products.

From Malvern Panalytical 4 Dec 2017

Fish oil component provides long-term preconditioning protection for vision cells

A team of LSU Health New Orleans scientists discovered that a component of fish oil not only protects cells critical to vision from potentially lethal initial insults, but also from those that occur in the future.

1 Dec 2017

Scientists use computer analysis to complete antibody blueprint

Antibodies defend our bodies against intruders. These molecules consist of proteins with attached sugars. However, the blueprint directing the processing of these sugars on the protein was not well understood until now.

30 Nov 2017

Researchers create first semi-synthetic organism that can store and use unnatural genetic information

Researchers from The Scripps Research Institute (TSRI) have designed a bacterium that incorporates two unnatural bases, called X and Y, into genes, in addition to the four natural DNA bases − G, C, A and T − that usually code for proteins.

30 Nov 2017

USC researchers propose rules for making ribs

Scientists from the USC Stem Cell lab of Francesca Mariani recently shared a recipe for ribs, and it doesn't even require barbecue sauce.

29 Nov 2017

Researchers solve 3D structure of primary optogenetic tool

An international team of researchers from the Moscow Institute of Physics and Technology, Forschungszentrum Jülich, the European Synchrotron Radiation Facility, the Institut de Biologie Structurale, and the Max Planck Institute of Biophysics has determined the 3-D structure of channelrhodopsin 2, a membrane protein widely used in optogenetics to control nerve cells with light.

28 Nov 2017

Johns Hopkins researchers crack key part of mystery surrounding proteins

What makes the body of a person or any other organism work can, for the most part, be summed up in a word: proteins.

28 Nov 2017

Studies on evolutionary origin of teeth, vertebra illuminate human link to marine organisms

Two new studies on the evolutionary origin of teeth and of vertebra further illuminate the human connection to marine organisms that goes back millions of years.

23 Nov 2017

Study finds sensors to detect biomarkers

A new study conducted at Purdue University suggests that small vibrating sensors or microelectromechanical resonators can be used to identify biological markers in small amounts of blood. This method is expected to be useful for detecting a myriad of diseases, infections, and different medical conditions in their early stages.

21 Nov 2017

New mechanism in cancer cells to disarm attacking immune cells, study reveals

A new study, published in the Journal of Clinical Investigation, identified a substance Gdf-15, which is secreted by pancreatic cancer cells and shields cancerous cells from attack by immune cells known as macrophages.

21 Nov 2017

Probing living cells with AFM

An interview with Prof. David Alsteens, Université Catholique de Louvain conducted by April Cashin-Garbutt, MA (Cantab).

From Bruker Nano Surfaces and Metrology 21 Nov 2017

Simple mirror technique boosts the performance of diSPIM, study says

Researchers from the Marine Biological Laboratory (MBL) have significantly improved the efficiency, resolution, and speed of a light-sheet microscope, by using a simple mirror technique and not-so-easy computational analysis, with a wide range of applications for better imaging of embryos and live cells.

20 Nov 2017

Study records video of colliding organic nanoparticles

A new study conducted at the Northwestern University, published today in the Journal of the American Chemical Society, captured a video of organic nanoparticles colliding and fusing together, a breakthrough in nanotechnology.

20 Nov 2017

Leaf-eating ability of beetle largely due to bacteria inside the insect

A leaf-eating beetle has evolved a symbiotic relationship with bacteria that allows the insect to break down pectin -- part of a plant's cell wall that is indigestible to most animals.

17 Nov 2017

Biologists resolve immune protein structure to provide insight into pathogen-defense strategies

Biologists have resolved the structure of a ring of proteins used by the immune system to summon support when under attack, providing new insight into potential strategies for protection from pathogens.

17 Nov 2017

Researchers map first-ever proteome of healthy human heart

A healthy heart beats about two billion times during a lifetime – thanks to the interplay of more than 10,000 proteins. Researchers from the Max Planck Institute of Biochemistry and the German Heart Centre at the Technical University of Munich have now determined which and how many individual proteins are present in each type of cell that occurs in the heart.

17 Nov 2017

Molecular & Structural Biology

Researchers develop molecular beacon to find hypoxic spots in real time

Researchers establish function of long RNA strands in skin development and disease

Biological Applications of AFM

Overcoming Challenges of Assays of Complex Cellular Models with Real-Time Live-Cell Analysis

Malvern Panalytical Announce Efforts Towards a Platform For Protein Aggregation Profiling

Fish oil component provides long-term preconditioning protection for vision cells

Scientists use computer analysis to complete antibody blueprint

Researchers create first semi-synthetic organism that can store and use unnatural genetic information

USC researchers propose rules for making ribs

Researchers solve 3D structure of primary optogenetic tool

Johns Hopkins researchers crack key part of mystery surrounding proteins

Studies on evolutionary origin of teeth, vertebra illuminate human link to marine organisms

Study finds sensors to detect biomarkers

New mechanism in cancer cells to disarm attacking immune cells, study reveals

Probing living cells with AFM

Simple mirror technique boosts the performance of diSPIM, study says

Study records video of colliding organic nanoparticles

Leaf-eating ability of beetle largely due to bacteria inside the insect

Biologists resolve immune protein structure to provide insight into pathogen-defense strategies

Researchers map first-ever proteome of healthy human heart

Bioprocess Efficiency with Cell Density Monitoring

Exploring electron microscopy for plant and microbial imaging at the John Innes Centre

Extending the reach of Amperia™

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