Molecular & Structural Biology

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Study highlights the robustness of miRNA modulation during aging process

Aging-US published "miRNAs generated from Meg3-Mirg locus are downregulated during aging" which reported that Aging determines a multilevel functional decline and increases the risk for cardiovascular pathologies.

28 Aug 2021

Mystery of roe deer embryonic diapause revealed

Everyone is familiar with the roe deer, either from crossword puzzles or from real-life encounters during a jog or a hike in the forest: majestic creatures with elegant big black eyes.

28 Aug 2021

Research analyzes the role of RNA tags in Alzheimer’s disease

Understanding the role of tau protein in Alzheimer's disease (AD) has led to new ways to diagnose it as well as the creation of medicines now in clinical trials to treat it.

28 Aug 2021

Rice lab receives NIH grant to unravel DNA’s secrets

The poor bacteriophages in Yang Gao's lab are about to have a lot of bad days.

28 Aug 2021

New machine learning techniques help resolve structural biology challenges

Determining the 3D shapes of biological molecules is one of the hardest problems in modern biology and medical discovery. Companies and research institutions often spend millions of dollars to determine a molecular structure – and even such massive efforts are frequently unsuccessful.

27 Aug 2021

New machine learning method enhances computational prediction of RNA structures

Researchers present ARES (Atomic Rotationally Equivariant Scorer) – a machine learning method that significantly improves the computational prediction of RNA structures over previous approaches. Like proteins, RNA molecules twist and fold into intricate three-dimensional shapes that are crucial to their function.

27 Aug 2021

Restoring DAXX protein levels may prevent misfolding of rogue proteins known to drive Alzheimer's

For the first time, Penn Medicine researchers showed how restoring levels of the protein DAXX and a large group of similar proteins prevents the misfolding of the rogue proteins known to drive Alzheimer's and other neurodegenerative diseases, as well as certain mutations that contribute to cancers.

26 Aug 2021

Old habit-controlling neurons may also play a critical role in new action learning

Imagine working on your computer and typing the same long password you have used for years to access your email.

26 Aug 2021

Penn study shows how certain proteins have evolved to suppress cheating chromosomes

Eggs and sperm are special cells for many reasons, but one of the characteristics that sets them apart is that, unlike other human cells, which have two copies of 23 chromosomes, one from the mother and one from the father, these sex cells, or gametes, have only one.

25 Aug 2021

Princeton researchers build world's smallest mechanically interlocked biological structure

Researchers at Princeton University have built the world's smallest mechanically interlocked biological structure, a deceptively simple two-ring chain made from tiny strands of amino acids called peptides.

25 Aug 2021

Study suggests a balanced approach to developing safer opioid analgesics

Opioids are powerful painkillers but their use is hindered because patients become tolerant to them, requiring higher and higher doses, and overdoses can cause respiratory depression and death.

24 Aug 2021

Researchers discover molecule that plays an important role in sperm motility regulation

About 120 million unintended pregnancies occurred each year between 2015 and 2019 worldwide. While there are oral contraceptives for women, the development of oral contraceptives for men has not been successful.

24 Aug 2021

Pericentromeric noncoding RNA provokes inflammatory gene expression in senescence and cancer

Research from the Cancer Institute at the Japanese Foundation for Cancer Research (JFCR), which was published today (August 23, at 3 pm US ET) in the leading international scientific journal Proceedings of the National Academy of Sciences of the United States of America, reveals that noncoding RNA derived from pericentromeric repetitive sequences provokes inflammatory gene expression in senescence and cancer.

24 Aug 2021

Atomic-level imaging of infectious prions reveals new therapeutic targets for untreatable diseases

The highest-ever resolution imaging of an infectious prion provides the first atomic-level data of how these abnormal proteins are assembled to cause fatal neurodegenerative diseases in people and animals - and how they can be potentially targeted by new therapies.

24 Aug 2021

Researchers use DNA barcoding to test food products claiming to have ‘wild mushrooms’

Harvesting wild mushrooms requires an expert eye to distinguish between the delicious and the inedible. Misidentification can have a range of consequences, from a disgusting taste and mild illness to organ failure and even death.

23 Aug 2021

Researchers use gene editing to render male mosquitoes infertile and slow disease spread

Mosquitos spread viruses that cause potentially deadly diseases such as Zika, dengue fever and yellow fever. New U.S. Army-funded research uses gene editing to render certain male mosquitoes infertile and slow the spread of these diseases.

23 Aug 2021

Researchers develop an integrative approach to boost accuracy of mosquito vector surveillance

A team of researchers from the National University of Singapore, led by Assistant Professor Nalini Puniamoorthy from the Department of Biological Sciences, has developed an integrative approach that increases the accuracy of mosquito surveillance and management.

20 Aug 2021

Molecular & Structural Biology

Study highlights the robustness of miRNA modulation during aging process

Mystery of roe deer embryonic diapause revealed

Research analyzes the role of RNA tags in Alzheimer’s disease

Rice lab receives NIH grant to unravel DNA’s secrets

New machine learning techniques help resolve structural biology challenges

New machine learning method enhances computational prediction of RNA structures

Restoring DAXX protein levels may prevent misfolding of rogue proteins known to drive Alzheimer's

Old habit-controlling neurons may also play a critical role in new action learning

Penn study shows how certain proteins have evolved to suppress cheating chromosomes

Princeton researchers build world's smallest mechanically interlocked biological structure

Study suggests a balanced approach to developing safer opioid analgesics

Researchers discover molecule that plays an important role in sperm motility regulation

Pericentromeric noncoding RNA provokes inflammatory gene expression in senescence and cancer

Atomic-level imaging of infectious prions reveals new therapeutic targets for untreatable diseases

Researchers use DNA barcoding to test food products claiming to have ‘wild mushrooms’

Researchers use gene editing to render male mosquitoes infertile and slow disease spread

Researchers develop an integrative approach to boost accuracy of mosquito vector surveillance

Northwestern scientists discover remarkable longevity in a subset of mitochondrial proteins

Regular physical exercise modulates iron metabolism in Alzheimer’s mouse model

SARS-CoV-2 mutations alter dynamics of neutralizing antibodies

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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