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Findings from the CoVaccS study on parental intention to vaccinate children against COVID

In the current preprint posted to the medRxiv* server, the researchers looked at UK parental intention to vaccinate their children during a time of selective pediatric vaccination.

24 May 2022

Efficacy study of Paxlovid and Molnupiravir in real-world settings shows positive results

In a recent study posted to the medRxiv* pre-print server, researchers evaluated the effectiveness of oral severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antivirals, molnupiravir (Lagevrio) or nirmatrelvir/ritonavir (Paxlovid) in a real-world setting.

24 May 2022

BNT162b2 vaccine induces robust SARS-CoV-2 immunity in children

In a recent study posted to the medRxiv* pre-print server, researchers evaluated coronavirus disease 2019 (COVID-19) vaccine-induced humoral immune response in five to 11-year-old children.

23 May 2022

Olverembatinib a potent inhibitor of Omicron NTD-mediated cytokine release

Researchers determine whether mutations in the Omicron NTD influence its potential to stimulate myeloid cells and enhance inflammatory cytokine release.

22 May 2022

Novel brain-permeable Cdk5 inhibitor alters neurobehavior in mice

James Bibb, Ph.D., and colleagues have described a novel preclinical drug that could have the potential to combat depression, brain injury and diseases that impair cognition. The drug, which notably is brain-permeable, acts to inhibit the kinase enzyme Cdk5.

20 May 2022

Medicinal cannabis can be considered as alternative to pain relief medicines for cancer patients

A comprehensive assessment of the benefits of medical cannabis for cancer-related pain found that for most oncology patients, pain measures improved significantly, other cancer-related symptoms also decreased, the consumption of painkillers was reduced, and the side effects were minimal.

20 May 2022

Glaucoma treatment using smart contact lenses that release drugs

In a recent study published in the journal Nature Communications, researchers developed a wireless theranostic contact lens (WTCL) sensor for sensing intraocular pressure (IOP) in situ and delivering anti-glaucoma drugs on-demand.

19 May 2022

Researchers examine link between long-term use of blood pressure drugs and breast cancer risk

Curtin University researchers will examine if the long-term use of a popular blood pressure medication increased the risk of breast cancer in almost 200,000 women as part of a new project supported by the Federal Government.

19 May 2022

Evaluating efficacy of SARS-CoV-2 antivirals in a mouse model

In a recent study posted to the bioRxiv* pre-print server, researchers from Belgium evaluated the efficacy of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antiviral drugs in a severe combined immunodeficient (SCID) mouse model.

18 May 2022

Recombinant protein vaccine stands up to SARS-CoV-2 variants

A study by researchers in Texas describes a mouse model in which a subunit vaccine with alum-CpG adjuvant was tested for its ability to induce a broadly neutralizing antibody response against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

18 May 2022

The impact of NSAIDs on COVID-19 severity

Researchers examine potential correlations between NSAID use and COVID-19 severity.

18 May 2022

High-risk prescribing practices associated with increased risk of disability among older adults

For many, good health and longevity is only achievable with the help of prescription drugs. However, researchers in Japan have recently identified that some "high-risk" prescribing practices may be a cause for concern among older adults.

18 May 2022

Discovery of a potent SARS-CoV-2 RBD specific human monoclonal antibody

A recent article posted to the bioRxiv* preprint server demonstrated structural underpinnings of the neutralization of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variants by 002-S21F2, an extensive SARS-CoV-2 neutralizing antibody.

18 May 2022

The efficacy of CoronaVac against SARS-CoV-2 in cancer patients

In a recent study published in the Journal of Medical Virology, researchers analyzed the efficacy of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines in preventing SARS-CoV-2 infection among cancer patients.

18 May 2022

Patients with COVID-19 pneumonitis and moderate to severe ARDS treated with sildenafil

A new study published in the British Journal of Anaesthesia aimed to determine whether sildenafil could improve gaseous exchange in patients with COVID-19 ARDS with pulmonary hypertension, RV dysfunction, or both.

17 May 2022

Polypharmacy can lead to harmful drug interactions, especially among cancer patients

Here's a scenario so common that it applies to nearly 92 percent of older adults with cancer: An individual comes in for treatment and reports taking several medications that might include a drug for high blood pressure or heart disease, an antidepressant, or something for diabetes.

17 May 2022

3rd dose of COVID mRNA vaccine expands memory and capacity of immune system to combat Omicron

Researchers from the United States have now found that the immune recall induced by a two-dose primary series of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination after an initial natural infection highly improves the longevity of the antibodies as well as induces an enhanced breadth of protection across the SARS-CoV-2 variants.

17 May 2022

Study reveals psychological benefits of statins

Statins have been hailed as a wonder drug; the cholesterol-lowering drugs have been prescribed to tens of millions of people since their approval in the late 1980s to prevent heart attack and stroke.

17 May 2022

Neutralization of SARS-CoV-2 by plant-made neutralizing monoclonal antibodies

In a recent study published in the journal Vaccines, researchers developed plant-based monoclonal antibodies (mAbs) against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2).

17 May 2022

A study of SARS-CoV-2-mRNA booster vaccinations in immunocompromised patients

In a recent study published in the journal Frontiers in Immunology, researchers assessed the immune responses induced by vaccination with the messenger ribonucleic acid (mRNA)-1273 vaccine or the BNT162b2 vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections among immunocompromised individuals.

17 May 2022

Pharmaceutical News

Findings from the CoVaccS study on parental intention to vaccinate children against COVID

Efficacy study of Paxlovid and Molnupiravir in real-world settings shows positive results

BNT162b2 vaccine induces robust SARS-CoV-2 immunity in children

Olverembatinib a potent inhibitor of Omicron NTD-mediated cytokine release

Novel brain-permeable Cdk5 inhibitor alters neurobehavior in mice

Medicinal cannabis can be considered as alternative to pain relief medicines for cancer patients

Glaucoma treatment using smart contact lenses that release drugs

Researchers examine link between long-term use of blood pressure drugs and breast cancer risk

Evaluating efficacy of SARS-CoV-2 antivirals in a mouse model

Recombinant protein vaccine stands up to SARS-CoV-2 variants

The impact of NSAIDs on COVID-19 severity

High-risk prescribing practices associated with increased risk of disability among older adults

Discovery of a potent SARS-CoV-2 RBD specific human monoclonal antibody

The efficacy of CoronaVac against SARS-CoV-2 in cancer patients

Patients with COVID-19 pneumonitis and moderate to severe ARDS treated with sildenafil

Polypharmacy can lead to harmful drug interactions, especially among cancer patients

3rd dose of COVID mRNA vaccine expands memory and capacity of immune system to combat Omicron

Study reveals psychological benefits of statins

Neutralization of SARS-CoV-2 by plant-made neutralizing monoclonal antibodies

A study of SARS-CoV-2-mRNA booster vaccinations in immunocompromised patients

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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